Linkage disequilibrium (LD) matrices are an essential part of many statistical genetics methods. However, their high dimensionality makes their computation and storage impractical for large genomic da...

With the increasing availability of high quality genomic data from diverse cohorts, polygenic scores (PRS) have become a mainstay of genetic analyses of complex traits and diseases. Despite their prol...

Watchdog’s report warns new era of DNA-based criminal investigations calls for clearer rules and more transparency

Here the authors analyze de novo mutations in >10,000 parent-offspring trios and find that ancestry and smoking independently associate with mutation rate, but that common genetic variants likely c...

Canada Excellence Research Chairs (CERC)

Mon «alma mater» a préféré jouer de surobéissance préventive pour ne pas froisser le gouvernement Trump.

Describing the distribution of genetic variation across individuals is a fundamental goal of population genetics. We present a method that capitalizes on the rich genealogical information encoded in g...

Gene genealogies represent the ancestry of a sample and are often encoded as ancestral recombination graphs (ARG). It has recently become possible to infer these gene genealogies from sequencing or ge...

The department of Biology in the Faculty of Arts and Science at Concordia University invites applications for a tenure-track faculty position with the opportunity to apply for a Tier II Canada Researc...

While the use of genetically defined population descriptors in human research studies has been proposed to reduce inaccuracies and harms associated with the use of conventional, non-biologically based...

With improved Whole Genome Sequencing (WGS) and variant imputation techniques, modern Genome-wide Association Studies (GWASs) have enriched our understanding of the landscape of genetic associations f...

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