Happy to share the latest of Ollila lab! Many hypotheses turned out wrong along the way, but we found an additional piece to the fascinating puzzle how mesenchyme shapes intestinal epithelium. Toni Lemmetyinen did most if the mork, big thanks to all contributors! pubmed.ncbi.nlm.nih.gov/39634560/
pubmed.ncbi.nlm.nih.gov
Mesenchymal GDNF promotes intestinal enterochromaffin cell differentiation - PubMed
Enteroendocrine cells (EECs) differentiate and mature to form functionally distinct populations upon migration along the intestinal crypt-villus axis, but how niche signals affect this process is poor...