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Rainer Machné

@selfsplicing.bsky.social
150 followers 577 following 26 posts

i splice myself when i think about o2

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Rainer Machné @selfsplicing.bsky.social · 13/08/2026
Ocean surface temperatures at an El-nino-monitoring site in the equatorial Pacific Ocean. Crazy times. In November 2015 (top gray line) it went higher than it is currently (red line), and continued at max. levels throughout summer 2016.
screenshot from https://climatereanalyzer.org/clim/sst_daily/?dm_id=nino3.4 on 2026-08-13
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Rainer Machné @selfsplicing.bsky.social · 25/06/2026
Still cooler then outside. It's Gazpacho time.
a gazpacho with an ice cube, mint leaves, and balsamico creme. Room temperature: 31.8 C, humidity: 73%.
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Rainer Machné @selfsplicing.bsky.social · 15/07/2025
Finding causal structures behind correlations is a key task of science. In biology, we have to do that for evolved, highly connected homeostatic feedback systems. How? Moving from "pseudo steady state" assumptions to time series may be the only option.
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Rainer Machné @selfsplicing.bsky.social · 04/07/2025
Unpopular opinion: I love posters and find them underrated as a form of less linear science communication. There should be platforms to publish in poster format, with supporting online material. My latest one, I loved to present in the Bohemian woods #theconferencetoendallconferences #tcteac
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Rainer Machné @selfsplicing.bsky.social · 14/06/2025
Ah thanks. I didn't see the creepy babies, but the spider man at the river may be Cžerny as well then.
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Rainer Machné @selfsplicing.bsky.social · 09/06/2025
More support for the relevance of the twin-domain model of transcription by Sam Meyer's lab: gyrase binding is increased many kb downstream of highly expressed genes, topoI upstream. Context matters. academic.oup.com/nar/article/...
topoisomerase I and gyarse binding upstream and downstream of transcription units
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