Liu et al. show that dietary protein sources differentially restrict colonization of the pathogen Vibrio cholerae. Specific diets downregulate V. cholerae type VI secretion system (T6SS) expression, l...

Clinical use of engineered bacteriophages for the treatment of disseminated mycobacterial infection.

Bacteriophages (phages) are viruses that exclusively infect bacteria and cannot replicate within eukaryotic cells in the absence of their bacterial host. Discovered in 1915 (1, 2), more than 10 years ...

Antimicrobial peptides (AMPs) are promising alternatives to classical antibiotics against antibiotic-resistant pathogens. TAT-RasGAP317-326 is an AMP with broad range antibacterial activity, but its m...

A new fungal species, Penicillium psychrofluorescens sp. nov. is described as a member of section Torulomyces. The new species is sister to P. catalonicum, and was isolated from soil collected from...

Kansas public health officials say the state's ongoing tuberculosis outbreak is the largest since the CDC started reporting TB cases in the 1950s.

At the present time, based on available information, FAO-WHO-WOAH assess the global public health risk of influenza A(H5N1) viruses to be low, while the risk of infection for occupationally exposed pe...

Between 24 October and 5 December 2024, Panzi health zone in Kwango Province of Democratic Republic of the Congo recorded 406 cases of an undiagnosed disease with symptoms of fever, headache, cough, r...

This cohort study investigates the association of neighborhood fine particulate matter air pollution exposure with death or graft failure among lung transplant recipients.

Borreliella burgdorferi, the primary causative agent of Lyme disease in North America (1, 2), is the most common tick-borne pathogen in the northern hemisphere (3, 4). The American College of Veterinary Internal Medicine recommends that dogs residing in, or near, endemic regions for Lyme disease be screened yearly for exposure to tick-borne pathogens (5). In 2023, the Companion Animal Parasite Council (CAPC) reported that 465,700 dogs in the United States tested positive for antibodies (Abs) to B. burgdorferi. The actual number of positive tests is much higher as only about 1/3 of test results are cataloged by CAPC. Antibiotic therapy generally results in positive clinical outcomes when canine Lyme disease is diagnosed and treated early (5). However, if untreated, transient intermittent lameness, polyarthritis, and potentially fatal nephritis may develop.

Rationale: Fibrotic hypersensitivity pneumonitis (FHP) is a debilitating interstitial lung disease driven by incompletely understood immune mechanisms.

Accumulation of genetic variations including large-sized mutations in Mycobacterium tuberculosis’s genes associated with tuberculosis patient outcomes and bacterial antibiotic resistance ability.