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Sean Coakley

@seancoakley.bsky.social
434 followers 517 following 21 posts

Lab head and neuroscientist at the School of Biomedical Sciences at The University of Queensland 🇦🇺🧠🔬 www.coakleylab.com

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Reposted by Sean Coakley
Coakley Lab @coakleylab.bsky.social · 29/01/2026
Thanks to The University of Queensland for highlighting our discovery of a nanoscale scaffold, in the tissue that surrounds the axon, that protects sensory axons from degenerating. news.uq.edu.au/2026-01-plea... @hilliardlab.bsky.social
news.uq.edu.au
Pleasure and pain: tiny worm reveals secret to protecting skin sensations
A tiny roundworm has helped UQ scientists uncover miniscule structures in skin tissue that may protect the body’s ability to feel temperature, touch and pain.
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Reposted by Sean Coakley
Christophe 🔬 Leterrier @christlet.bsky.social · 08/01/2026
The MPS visits the axon's neighbors! Interesting results from @hilliardlab.bsky.social & @coakleylab.bsky.social in C. elegans where the epidermis forms a submembrane axon-imprinted periodic spectrin skeleton that restrict the endocytosis of cell surface proteins: doi.org/10.1126/scia...
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Reposted by Sean Coakley
Mehershad Wadia @mehershadw.bsky.social · 09/01/2026
Excellent work from @coakleylab.bsky.social and @hilliardlab.bsky.social 👏 Turns out, neurons protect themselves by literally becoming thick-skinned.
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Reposted by Sean Coakley
Coakley Lab @coakleylab.bsky.social · 08/01/2026
Latest paper is now out and features on the cover of Science Advances 👉 tinyurl.com/vea5862x Very grateful Igor Bonacossa Pereira, Dat Le & Massimo Hilliard @hilliardlab.bsky.social for their creativity & passion. Read more about it 👉 tinyurl.com/56awjda5 & 👉 tinyurl.com/2vp8p8uk
tinyurl.com
An epidermal membrane-associated periodic skeleton restricts endocytosis to stabilize neuron-epidermal attachment and preserve axons
An epidermal membrane periodic scaffold protects axons from damage.
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Reposted by Sean Coakley
Jenny Stow @jennystowlab.bsky.social · 04/12/2025
#NHMRC responses at #Estimates were deeply inadequate, uninformed and are not going to #SaveOzScience. #NHMRC has NOT requested more funding to save the majority of excellent science. Our science, our scientists and the public deserve better. Thankyou #DavidPocock and #DrMoniqueRyan.
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Reposted by Sean Coakley
Australasian Neuroscience Society @ausneurosoc.bsky.social · 01/07/2025
July fun fact! #ANS2025 #AusNeuro Bring your Tassie tuxedos (aka puffer jackets)! As one of the southernmost capital cities in the world, Hobart is closer to Antarctica than it is to Darwin.
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Reposted by Sean Coakley
Australasian Neuroscience Society @ausneurosoc.bsky.social · 30/06/2025
🚨 Deadline for Abstracts closes 17:00 AEST, Monday 7 July 2025 🚨 🔬🧬🧠Abstract submission for the #ANS2025 Annual Scientific Meeting in Hobart, Tasmania close soon!🔬🧬🧠 Submit your abstract Here: tas.currinda2.com/register/eve... We look forward to seeing you in Hobart!
tas.currinda2.com
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Sean Coakley @seancoakley.bsky.social · 29/05/2025
A watched manuscript never gets reviewed
media.tenor.com
a pot of boiling water is sitting on a stove .
ALT: a pot of boiling water is sitting on a stove .
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Sean Coakley @seancoakley.bsky.social · 20/05/2025
Daily reminder that life's a rollercoaster 🎢 #celegans #dadjokes and coaster by @mehershadw.bsky.social
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Reposted by Sean Coakley
Coakley Lab @coakleylab.bsky.social · 19/05/2025
What a fantastic gift from Red, our undergrad rotation student this semester. A needle felt C. elegans! Thank you Red 🙏#worm #celegans #scienceart #science
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Australasian Neuroscience Society @ausneurosoc.bsky.social · 23/04/2025
Alright, Aus Neuro fam! 👋 We've just dropped a new ANS starter pack over at go.bsky.app/B8viKca and it's feeling a little... empty. 🤔 Hit that link and drop your suggestions – let's make this pack legendary! ✨ #bluesky #starterpack #suggestions #ANS #AusNeuro 🇦🇺🧠
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Reposted by Sean Coakley
Sean Coakley @seancoakley.bsky.social · 04/04/2025
A little piece I wrote for the conversation on the role of curiosity in medical breakthroughs 👇 theconversation.com/curiosity-dr...
theconversation.com
‘Curiosity-driven research’ led to a recent major medical breakthrough. But it’s under threat
Curiosity-driven research is exactly what it sounds like: research driven by the goal of understanding nature without regard for application.
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Sean Coakley @seancoakley.bsky.social · 04/04/2025
They... used the force
media.tenor.com
a close up of a statue of yoda from star wars smoking a cigar .
ALT: a close up of a statue of yoda from star wars smoking a cigar .
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Sean Coakley @seancoakley.bsky.social · 04/04/2025
A little piece I wrote for the conversation on the role of curiosity in medical breakthroughs 👇 theconversation.com/curiosity-dr...
theconversation.com
‘Curiosity-driven research’ led to a recent major medical breakthrough. But it’s under threat
Curiosity-driven research is exactly what it sounds like: research driven by the goal of understanding nature without regard for application.
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Reposted by Sean Coakley
ARC Tracker @arc-tracker.bsky.social · 27/02/2025
The ARC have tweeted that they will released Discovery Projects Expression of Interest outcomes tomorrow.
Screenshot of a tweet from the ARC saying the following: "DP26 EOI applicants: tomorrow all lead CIs will receive an email with their outcomes and all applicants will be able to get their results in RMS. Due to the volume of applications, emails may be staggered throughout the day. Stay tuned for an update.".
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Sean Coakley @seancoakley.bsky.social · 27/02/2025
This looks like a fabulous meeting! Abstract submission and registration close soon so don't miss out. Cell biology ✔️ nervous system ✔️ Greece ✔️ 🔬🤓🧠🇬🇷
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Sean Coakley @seancoakley.bsky.social · 12/02/2025
Fantastic first day of #SMP2025 Bill Shorten's masterclass on civics was a highlight. Great to have the opportunity to chat with Minister Ed Husic at the gala dinner about the benefits of basic science and the culture of curiosity to drive innovation and economic benefits for all Australians 🧠🔬🤓
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Sean Coakley @seancoakley.bsky.social · 24/01/2025
This paper is now featured by @naturecomms.bsky.social on their Editors' Highlights page Check it out 👇 www.nature.com/collections/...
nature.com
From molecules and cells to organisms
This page highlights recent articles advancing our knowledge in molecular, cell and developmental biology, including disciplines as diverse as cell division, ...
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Reposted by Sean Coakley
Mehershad Wadia @mehershadw.bsky.social · 23/01/2025
Our paper is now featured in the Editors' highlights at @naturecomms.bsky.social 👇 www.nature.com/collections/...
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Reposted by Sean Coakley
Mehershad Wadia @mehershadw.bsky.social · 19/01/2025
NEW Paper: If you're a fan of Rachel from 'Friends', you would love OSP-1, as it is also protective of ROS Donato et al. found a novel gene OSP-1 (oxidative stress protective 1) that protects neurons from damage caused by reactive oxygen species (ROS), by modulating autophagy.👇
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Sean Coakley @seancoakley.bsky.social · 03/01/2025
Nice way to start the year. An enormous effort on this one from Alessandra. Congratulations! 🎉
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Reposted by Sean Coakley
evakaulich.bsky.social @evakaulich.bsky.social · 03/01/2025
Leveraging the genetic power of the nematode C. elegans and the optogenetic tool KillerRed, the Hilliard Lab discovered osp-1, a novel gene that protects neurons from oxidative damage via cell-autonomous mechanisms 🧠 doi.org/10.1038/s414...
doi.org
OSP-1 protects neurons from autophagic cell death induced by acute oxidative stress - Nature Communications
How oxidative stress impacts neurons is poorly understood. Here the authors reveal that overactivation of autophagy following oxidative stress contributes to neuronal death and discover a protective f...
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Sean Coakley @seancoakley.bsky.social · 15/12/2024
What happens if I only eat tacos for 5 days? Asking for a friend... #CellBio2024
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Sean Coakley @seancoakley.bsky.social · 15/12/2024
I'll be presenting our work from @coakleylab.bsky.social #CellBio2024 where we discovered a periodic spectrin skeleton in the skin of C. elegans that protects neurons from damage. Come say hi 👋 P1427 Sunday 15th 11:15am-12:45pm @ascbiology.bsky.social
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Sean Coakley @seancoakley.bsky.social · 30/11/2024
Very happy and proud about this week's success. Very grateful to all my colleagues and my lab for their hard work and support getting this over the line 🍾🙏🥳
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Franciska de Vries 🟥 @frantecol.bsky.social · 28/11/2024
Science takes time - a lot of time. Time that is more and more difficult to make available because of increased workloads. Time that exceeds the temporary contracts of postdocs and PhDs. I'll illustrate this using our paper published in Nature yesterday. 🧵 (1/x) www.nature.com/articles/s41...
nature.com
Soil microbiomes show consistent and predictable responses to extreme events - Nature
Soils from 30 grasslands across Europe were subjected to 4 contrasting extreme climatic events under drought, flood, freezing and heat conditions, with the results suggesting that soil microbiomes fro...
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Sean Coakley @seancoakley.bsky.social · 25/11/2024
Thinking of everyone who feels like they have a LOT riding on these. The sun will rise on Wednesday 🌞 #ARCDP25
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ARC Tracker @arc-tracker.bsky.social · 25/11/2024
ARC says they’ll release the Discovery Projects 2025 outcomes tomorrow. Recently, outcomes announcements have tended to happen at/around 11am Canberra time. My bot will pick up the announcement in RMS’s database and post immediately. Good luck!
Screenshot of a tweet from the ARC saying they’ll announce DP25 grant outcomes tomorrow (Tuesday 26 Nov).
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Sean Coakley @seancoakley.bsky.social · 21/11/2024
This is 🐎 💩. "Planning" to run a "system" in such a way is abusive behaviour. It's unacceptable, and entirely unsurprising.
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