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Rob Swanda

@scientistswanda.bsky.social

919 followers 25 following 600 posts

Making Science Accessible & Understandable | (educational purposes only, not medical advice) | www.youtube.com/c/RobSwandaPhD

Posts Replies Media

Rob Swanda @scientistswanda.bsky.social · 04/10/2026

Melanotan‑2 is a research peptide that activates melanocortin receptors to drive melanin production. Scientists explored it for photoprotection, but its receptor activity also affected appetite. My new video covers how MT‑2 interacts with receptors! youtu.be/pzdbqV3trVw

What is the Melanotan-2 (MT-2) Peptide?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 01/10/2026

Dacarbazine is one of those cancer drugs that looks simple but unleashes a powerful DNA‑damaging punch. After liver enzymes activate it, it disrupt DNA replication and pushes tumor cells toward cell death. Explore the full mechanism in my newest video! youtu.be/HZ37yvQO5DM

How does Dacarbazine (DTIC) Chemotherapy Work?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 30/09/2026

hahahaha 🤣 good point!! 🪱

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Rob Swanda @scientistswanda.bsky.social · 29/09/2026

Oxyclozanide is an antiparasitic that helps protect livestock from harmful internal parasites. Its mechanism disrupts the parasite’s ability to generate energy, weakening it from the inside out. Explore how this targeted approach works in my new lesson. youtu.be/nO50PxPBxns

How does Oxyclozanide work for Parasites?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 27/09/2026

Sermorelin is a research peptide that helps scientists explore how the body regulates growth hormones. Its mechanism offers a look at upstream signaling rather than directly replacing hormones. Learn more about how this pathway operates in my latest video! youtu.be/w1CLYgmMmyE

How does the Sermorelin Peptide Work?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 26/09/2026

I’m hosting a new series on early‑stage cancer research for the Cracking Cancer Podcast, and I’m looking for scientists who want to bring their work to life through powerful science communication. If you’d be interested in being a guest (or know someone who should be) plz reach out! 🤓

Rob Swanda @scientistswanda.bsky.social · 24/09/2026

Alzheimer’s research has expanded rapidly, with progress now happening across diagnostics, biomarkers, and therapeutics. New tools are helping detect disease earlier, understand it more clearly, and explore multiple treatment pathways. Learn more 👇 youtu.be/MXi-z90dP4Y

Recent Alzheimers Advancements

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 22/09/2026

Multiple sclerosis involves misdirected immune activity, and Gilenya was one of the first therapies to change how those immune cells move. It works by redirecting lymphocytes rather than eliminating them. Explore the full breakdown in my new video. youtu.be/DPLKBcbdz2k

How does Gilenya (Fingolimod) Work for MS?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 20/09/2026

In my new video, I break down how a mitochondrial-derived peptide responds to cellular stress and helps fine-tune how cells use fuel. If you’ve heard the buzz about MOTS-c in aging, exercise, or metabolic research, this lesson will explain it! youtu.be/G-EGnaa1uTs

How does the MOTS-c Peptide Work?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 17/09/2026

DAC chemistry turns a short‑acting biologic into a long‑acting therapeutic. By using a linker to bind albumin, the molecule stays in circulation far longer and releases its payload slowly over time. Learn how this modification is useful for biologics in my new video! youtu.be/xNBKzlIQRLs

DAC Half‑Life Extension for Peptides and Proteins

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 17/09/2026

you got that right a million percent!! 💯💯💯

Rob Swanda @scientistswanda.bsky.social · 17/09/2026

omg amazing!! I’ve been wanting to do a series on CAR-T … 🙌

Rob Swanda @scientistswanda.bsky.social · 15/09/2026

Praluent is a great example of how blocking a single protein can reshape cholesterol metabolism. By inhibiting PCSK9, it preserves LDL receptors on the liver and dramatically increases LDL clearance. Learn how this mechanism works in my new science video! youtu.be/L0GS8L3mZWA

How does Praluent (Alirocumab) Work to Reduce Cholesterol?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 15/09/2026

ahah always here to spread the knowledge of these fascinating innovations! 🤩

Rob Swanda @scientistswanda.bsky.social · 14/09/2026

TKIs and BTK inhibitors are targeted therapies that shut down key signaling pathways cancer cells rely on for survival. Each class blocks different kinase “switches,” shaping how they’re used across solid tumors & blood cancers. My latest lesson highlights how they work. youtu.be/NJXt-CVtrvA

TKIs vs BTKIs in Cancer Treatment

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 13/09/2026

SS-31 is an interesting mitochondria targeting peptide used in research today. By binding cardiolipin, it stabilizes the inner mitochondrial membrane to boost ATP output. Learn how this tiny peptide rewires mitochondrial efficiency in my new video! youtu.be/E2xhYiWNvk8

How does the SS-31 Peptide Work? (Elamipretide)

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 11/09/2026

Glutathione (GSH) is your body’s master antioxidant, working nonstop to neutralize oxidative stress and keep cells functioning at their best. Learn how this tiny molecule pulls off such a big job in my short explainer video! youtu.be/gtF7UV2Qncs

What is Glutathione (GSH)?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 10/09/2026

NAD⁺ and NADH are essential metabolic cofactors that shuttle electrons to power energy production. These molecules support ATP generation, DNA repair, and mitochondrial resilience. My latest lesson explains how this redox pair works! youtu.be/bdnSz5sQDoE

Overview of NAD+ / NADH

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 08/09/2026

Tesamorelin shows how activating a precise hormone pathway can reduce harmful visceral fat. This therapy targets deep abdominal adiposity linked to lipodystrophy. Check out my short lesson to learn more! youtu.be/DAs3mKbyvJA

How does Tesamorelin Work for HIV/AIDS Patients?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 07/09/2026

from what I could find, the materials selected are ones known to decay in a short period of time to minimize any off-target / residual effects 🧪

Rob Swanda @scientistswanda.bsky.social · 07/09/2026

this is a great point! and yes! some of these have a half-life (or begin decaying) in less than 2hrs! some a few days. and once they lose all their radioactive ability, they are just a standard compound, which will be excreted.

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Rob Swanda @scientistswanda.bsky.social · 07/09/2026

Radioligand therapy delivers radiation directly to cancer cells using molecular targeting, creating one of the most precise treatment approaches in oncology. These agents act like homing beacons and my new lesson explores how this strategy improves treatment accuracy! youtu.be/G5DhTP8XTkQ

How are Radioligands used in Cancer?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 06/09/2026

GHK‑Cu is a naturally occurring copper‑binding peptide widely studied for its regenerative and anti‑inflammatory potential. Researchers are exploring its role in tissue repair and cellular signaling. My new lesson breaks down how this small peptide works! youtu.be/Q19Lkc-GV7o

What is the GHK-Cu Peptide?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 04/09/2026

could you picture a single monthly GLP‑1 injection changing the game? well, Maritide is pushing that future forward! learn more in my short explainer! 😊 youtu.be/MdLhS-MUDQI

Monthly GLP-1: How does MariTide Work?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 03/09/2026

Rezdiffra is the first therapy designed to directly reactivate liver metabolism in MASH. By selectively targeting THR‑β, it reduces liver fat and improves fibrosis. I walk through how this liver‑specific mechanism works in my new video! youtu.be/E8DYjDMb4m4

How does Rezdiffra (Resmetirom) Work for MASH?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 01/09/2026

exactly! 😊

Rob Swanda @scientistswanda.bsky.social · 01/09/2026

Blinatumomab is one of the most precise immune‑engineering tools in modern oncology. It physically links T-cells to CD19+ leukemia cells to force targeted killing. I break down this mechanism as we enter Childhood Cancer Awareness Month. youtu.be/H3vJlqIGKYU

How does Blinatumomab (Blincyto) Work?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 30/08/2026

Ipamorelin is a research GH secretagogue studied in many pathways. It selectively activates the ghrelin receptor to trigger controlled, physiologic growth hormone pulses. Learn how this targeted signaling works in my new video. youtu.be/7iUeiZZTX1I

How does the Peptide Ipamorelin Work?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 28/08/2026

Metformin is one of the most important tools we have for keeping blood sugar in check & protecting long‑term metabolic health. To learn how it works, check out my short video! youtu.be/QkOsHUbZVF4

How does Metformin Work?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 27/08/2026

It’s that time of year again to breakdown the updated 2026–2027 COVID vaccine, which now targets the XFG variant. Will you be getting yours? youtu.be/O6vo2sKiPUk

New 2026 - 2027 Covid Vaccine

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 25/08/2026

yes so true! definitely unexpected last year!😭

Rob Swanda @scientistswanda.bsky.social · 25/08/2026

Flu season is upon us and the 2026–2027 flu vaccine was fully updated due to shifts in circulating H1N1, H3N2, and B/Victoria strains. I break it all down in my newest educational video! 😊 youtu.be/W_HeCIhJD7U

New Formulation: 2026 - 2027 Flu Shot

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 23/08/2026

ty! ♥️ those end results have not been published yet (as far as I know) and the companies mentioned they would be released later! current language used “met both its primary target of reducing cancer recurrence and its secondary goal of preventing tumors from spreading to other parts of the body”

Rob Swanda @scientistswanda.bsky.social · 23/08/2026

CJC‑1295 is a long‑acting GHRH analog designed to extend growth‑hormone signaling. Research also shows it sustains pituitary receptor activation rather than just replacing GH directly. I break down the evidence and mechanism in my new educational video! youtu.be/OBs1CBHLgvU

What is the CJC-1295 Peptide?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 21/08/2026

Last year I broke down the promising Phase 2 data behind the mRNA melanoma vaccine. With all the buzz from the latest positive updates on its progress, now’s the perfect time to remind you exactly how this treatment works! 😊 youtu.be/lCrR1JcPH-I

New Melanoma Treatment: Intismeran Autogene (Melanoma Vaccine) Explained

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 20/08/2026

Adtralza (EU designation) is a targeted biologic that calms the immune pathways in eczema. By blocking a key signal behind inflammation & itch, it helps restore healthier skin from the inside out. To learn how it works, watch my latest video! youtu.be/iYaFp6UQKOg

How does Adtralza (tralokinumab) Work for Psoriasis?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 18/08/2026

Enhertu is a major step forward in targeted cancer therapy by directly finding HER2+ tumor cells. This molecule increases cancer‑cell killing while limiting exposure to healthy tissues. Learn how it works in my latest video! youtu.be/M7n4ycv9uDo

How does Enhertu Work for HER2+ Cancers? (Breast Cancer Example)

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 18/08/2026

mRNA clinical trial for lung cancer!! let’s go 🫶 help spread the word, they are recruiting! youtube.com/shorts/Lwh48...

mRNA Lung Cancer Clinical Trial Recruiting! (INTerpath-009 Trial for NSCLC)

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 16/08/2026

Tecfidera is a MS therapy designed to protect nerve cells from inflammation. It works by reducing oxidative stress damage to neurons, which alleviates symptoms. In my new video, I break down how this mechanism works for patients! youtu.be/EZyDOLL2Dj0

How does Tecfidera Work for Multiple Sclerosis?

YouTube video by Dr. Rob Swanda

Reposted by Rob Swanda

Inflamed Procrastibaker @drtwillett.medsky.social · 14/08/2026

#ScienceSky and #MedSky folks should follow Dr Swanda for excellent explainer posts about lots of different molecules!

Rob Swanda @scientistswanda.bsky.social · 14/08/2026

appreciate your support so much, thank you!! 😊♥️

Rob Swanda @scientistswanda.bsky.social · 14/08/2026

Bispecific antibodies are engineered to latch onto two different molecules at once, helping cancer treatments hit tumors with more accuracy. Want a quick, simple breakdown of how they work? Watch my short video to learn more! youtu.be/takkdJ9wUzY

Using a Bispecific Antibody for Cancer Treatment

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 14/08/2026

wow awesome!! 👏

Rob Swanda @scientistswanda.bsky.social · 14/08/2026

appreciate you!! 😎

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Rob Swanda @scientistswanda.bsky.social · 13/08/2026

Bimagrumab is an investigational mAb that promotes muscle growth & prevents muscle loss. By inhibiting myostatin/activin signaling, it lifts the molecular “brakes” that normally limit muscle mass. Watch my new video to learn about the clinical studies. youtu.be/yLhXICUGh_Q

Investigation Muscle Protection Antibody: Bimagrumab

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 11/08/2026

Reclast protects our bones by shutting down overactive bone destroying cells. It binds tightly to bone surfaces and disrupts the mevalonate pathway, which reduces bone breakdown. Check out my new video to see how this once‑yearly infusion strengthens skeletal structure! youtu.be/lbCNN5CX1Kc

How does Reclast (Zoledronic Acid) Work for Osteoporosis?

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 09/08/2026

Taurine is a unique amino‑sulfonic acid that quietly supports mitochondrial stability. Inside cells, it helps maintain proper mitochondrial protein production. Watch my short video to learn how this small molecule plays a big role! youtu.be/gLpd4JsOOnU

Taurine & its Importance for the Mitochondria

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 07/08/2026

A few months ago I created a video explaining the technology, so I’ve linked it below if you’re curious about the mechanism of action. youtu.be/ImbCo1i1LRE

New mRNA Flu Vaccine (mFlusiva) Info

YouTube video by Dr. Rob Swanda

Rob Swanda @scientistswanda.bsky.social · 07/08/2026

A huge validation of mRNA as a flexible, fast, programmable platform just occurred, which modernizes how we tackle seasonal influenza. The first mRNA flu vaccine just earned FDA US approval for those 50yrs+

Rob Swanda @scientistswanda.bsky.social · 06/08/2026

Leqvio uses RNAi to turn down a liver protein that controls LDL recycling. By silencing PCSK9 production, it helps the body pull more LDL cholesterol out of the bloodstream with every pass through the liver. Check out my short video to see how this twice‑yearly therapy works! youtu.be/oD-nHZ-dM-Y

How does Leqvio (Inclisiran) Work to Reduce Cholesterol?

YouTube video by Dr. Rob Swanda