ScienceOpen @scienceopen.bsky.social · 11h𝐍𝐨 𝐚𝐜𝐭𝐢𝐨𝐧 𝐢𝐬 𝐫𝐞𝐪𝐮𝐢𝐫𝐞𝐝 𝐟𝐫𝐨𝐦 𝐮𝐬𝐞𝐫𝐬. We apologize for the temporary interruption and thank you for your patience. 𝐒𝐜𝐢𝐞𝐧𝐜𝐞𝐎𝐩𝐞𝐧 𝐰𝐢𝐥𝐥 𝐛𝐞 𝐛𝐚𝐜𝐤 𝐛𝐞𝐭𝐭𝐞𝐫 𝐚𝐧𝐝 𝐟𝐚𝐬𝐭𝐞𝐫. 000
ScienceOpen @scienceopen.bsky.social · 11hAll ScienceOpen data and services will be restored once the migration has been successfully completed. As ScienceOpen will not be accessible during this period, we recommend avoiding any planned publishing, reviewing, or promotional activities over that weekend. 100
ScienceOpen @scienceopen.bsky.social · 11h𝐄𝐱𝐩𝐞𝐜𝐭𝐞𝐝 𝐝𝐨𝐰𝐧𝐭𝐢𝐦𝐞: Friday, 9 October, evening CEST / afternoon EDT – Sunday, 11 October, 6 pm CEST / noon EDT 100
ScienceOpen @scienceopen.bsky.social · 11hScienceOpen is migrating its server infrastructure from the United States to Europe and upgrading our systems. To ensure a safe and consistent migration of all data, the ScienceOpen platform will be temporarily unavailable during this process. 100
ScienceOpen @scienceopen.bsky.social · 11h𝐒𝐜𝐢𝐞𝐧𝐜𝐞𝐎𝐩𝐞𝐧 𝐢𝐬 𝐦𝐨𝐯𝐢𝐧𝐠 𝐭𝐨 𝐄𝐮𝐫𝐨𝐩𝐞 𝐏𝐥𝐚𝐧𝐧𝐞𝐝 𝐢𝐧𝐟𝐫𝐚𝐬𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐞 𝐦𝐢𝐠𝐫𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐬𝐞𝐫𝐯𝐞𝐫 𝐮𝐩𝐠𝐫𝐚𝐝𝐞 100
ScienceOpen @scienceopen.bsky.social · 30/09/2026🔗 Celebrating 300 Publications with the Journal of Disability Research blog.scienceopen.com/2026/09/cele... 🔗 Journal of Disability Research www.scienceopen.com/collection/K...blog.scienceopen.comCelebrating 300 Publications with the Journal of Disability Research (JDR) – ScienceOpen BlogThe Journal of Disability Research has reached 300 publications, a milestone that reflects the journal’s rapid growth. ScienceOpen has been proud to host the JDR since its inception in 2022,… 000
ScienceOpen @scienceopen.bsky.social · 30/09/2026Read more about the journal, its success story, and its partnership with ScienceOpen on our blog post and explore valuable research articles in the journal's collection. 👇️ 101
ScienceOpen @scienceopen.bsky.social · 30/09/2026🎉 Congratulations to the Journal of Disability Research The Journal has just reached 300 Publications! — a highly anticipated milestone, exemplifying its success and its position as an established #OpenAccess journal in a field that helps empower and improve the quality of life for many people. 110
ScienceOpen @scienceopen.bsky.social · 29/09/2026 🔗 Explore the full Preprint of the Week on ScienceOpen: www.scienceopen.com/hosted-docum... 🔗 Checkout the ScienceOpen Preprints collection: www.scienceopen.com/collection/5...scienceopen.comRethinking Development ‘Of’ and ‘Through’ Sport: A Critical Analysis of Key Conceptual and Pedagogical Approaches for Sport as a Tool for Addressing Young People’s Intersection with Criminogenic Harms<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d27055576e79"><i>The intervention of sport in youth justice remains widely discussed and utilised, evident in the… 000
ScienceOpen @scienceopen.bsky.social · 29/09/2026🏆#PreprintOfTheWeek on #ScienceOpen🏆 The ScienceOpen Preprints Editorial Team congratulates Harry Michaels! Their preprint has attracted outstanding attention in the ScienceOpen community. Explore the preprint and discover more exciting research in the collection👇 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026drugrepocentral.scienceopen.com/collection/D...drugrepocentral.scienceopen.comDrug Repurposing Central<p>A publishing and communication platform for the whole drug repurposing community</p> 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026We leave with renewed optimism and inspiration, and look forward to next year. See you all there! Don't forget to check out all the conference proceedings and publications from the REPO4EU project on Drug Repurposing Central. 👇️ 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026As ScienceOpen, we're proud to provide the technology behind the project's publishing and scholarly dissemination needs. Our COO, Nina Tscheke, represented us at the event showcasing our work and chairing the session on Open Science, Research Integrity & Quality Publishing. 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026As a consortium member and part of the overall organisation, we are delighted to have helped provide this forum and deliver a good conference experience for everyone. 110
ScienceOpen @scienceopen.bsky.social · 25/09/2026 As attendees, we leave with great insights, inspiring new ideas, and connections with so many smart people from across the drug repurposing community. 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026And with that, #RExPO26 has concluded! 📢 Thank you to the whole consortium, the organisers, the speakers, poster presenters, session chairs, ambassadors, and all attendees for being part of this year's International Conference on Systems Medicine, AI & Drug Repurposing. 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Session Chair Christina Kyriakopoulou and all speakers from Session 11, now live on stage! 💬 We look forward to the Panel Discussion. 📢 Thank you to everyone joining us! 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome François Houÿez from EURORDIS, now live on stage! 💬 We look forward to François Houÿez's talk: "The EURORDIS Perspective on Drug Repurposing for Rare Diseases" 📢 Thank you to everyone joining us! 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comLessons From Two Years of Computational Drug Repurposing<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d3417151e125">Every Cure's computational pharmacophenomics platform has spent two years identifying the highest… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Amy Ford from Every Cure, now live on stage! 💬 We look forward to Amy Ford's talk: "Lessons From Two Years of Computational Drug Repurposing" 📢 Thank you to everyone joining us! 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comREPO-RARE: From Phenotypes to Spatial Disease Modules for Causal Therapy, Precision Medicine and Prevention<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d6544947e83">Current bioinformatics does not adequately represent disease mechanisms. Protein–protein… 010
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Harald Schmidt from Maastricht University, now live on stage! 💬 We look forward to Harald Schmidt's talk: "REPO-RARE: From Phenotypes to Spatial Disease Modules for Causal Therapy, Precision Medicine and Prevention" 📢 Thank you to everyone joining us! 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026 📢 Thank you to everyone joining us! 🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comBEACON: An Artificial Intelligence-Guided Drug Repurposing Platform Integrating Network Pharmacology and Functional Validation for Rare Neurodevelopmental Disorders<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d18460510e83">Rare neurodevelopmental disorders present a significant therapeutic challenge because pathogenic… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026💬 We look forward to Camerron Crowder's talk: "BEACON: An Artificial Intelligence-Guided Drug Repurposing Platform Integrating Network Pharmacology and Functional Validation for Rare Neurodevelopmental Disorders" 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Camerron Crowder from University of Alabama at Birmingham, now live on stage! 100
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Session Chair Harald Schmidt and all speakers from Session 10, now live on stage! 💬 We look forward to the Panel Discussion. 📢 Thank you to everyone joining us! 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comFrom Candidate to Patient: Exploring Drug Interactions and Population Considerations in Drug Repurposing<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d18416207e81">Repurposing a drug for a new indication may also mean exposing it to a fundamentally different… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Gregor Malischnig from PGXperts GmbH, now live on stage! 💬 We look forward to Gregor Malischnig's talk: "From Candidate to Patient: Exploring Drug Interactions and Population Considerations in Drug Repurposing" 📢 Thank you to everyone joining us! 111
ScienceOpen @scienceopen.bsky.social · 25/09/2026drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comDIGIT-HF - potential for EU-wide authorization of digitoxin for heart failure treatment<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d18352047e69">Heart failure still represents one of the leading causes for hospitalizations and death in… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Udo Bavendiek from Hannover Medical School, now live on stage! 💬 We look forward to Udo Bavendiek's talk: "DIGIT-HF - potential for EU-wide authorization of digitoxin for heart failure treatment" 📢 Thank you to everyone joining us! 111
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comDrug repurposing as an AI investment thesis: what has to change<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d104077e61">Bringing a new drug to market now costs more than $3 billion. The cost per approval keeps rising… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Thomas Hagemeijer from HGM Advisory, now live on stage! 💬 We look forward to Thomas Hagemeijer's talk: "Drug repurposing as an AI investment thesis: what has to change" 📢 Thank you to everyone joining us! 111
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comThe Complex Portal – Molecular Assemblies in Context<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1567415e77">The Complex Portal (www.ebi.ac.uk/complexportal) [1] is a manually curated reference database of… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Henning Hermjakob from EMBL-EBI, now live on stage! 💬 We look forward to Henning Hermjakob's talk: "The Complex Portal - Molecular Assemblies in Context" 📢 Thank you to everyone joining us! 111
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Session Chair Markus List and all speakers from Session 9, now live on stage! 💬 We look forward to the Panel Discussion. 📢 Thank you to everyone joining us! 011
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comTwinCell: Large Causal Cell Model for Reliable and Interpretable Therapeutic Target Prioritisation<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d97363e111">Drug development is a complex process requiring crucial decisions, starting with selecting the right… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Yann Abraham from DeepLife, now live on stage! 💬 We look forward to Yann Abraham's talk: "TwinCell: Large Causal Cell Model for Reliable and Interpretable Therapeutic Target Prioritisation" 📢 Thank you to everyone joining us! 111
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comNetwork-based drugresponse prediction, with multi-omics data: DrDimont and beyond<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d18420126e94">Predicting the effect of a drug or drug combination is a highly relevant task in precision… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Katharina Baum from Free University Berlin, now live on stage! 💬 We look forward to Katharina Baum's talk: "Network-based drug response prediction, with multi-omics data: DrDimont and beyond" 📢 Thank you to everyone joining us! 111
ScienceOpen @scienceopen.bsky.social · 25/09/2026📢 Thank you to everyone joining us! 🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comCerebral infarction as a threshold-sensitive network failure: NAIM as an in vivo platform for mechanism-based drug repurposing in ischemic stroke<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d6883740e85">Why one brain infarcts while another survives the same large-artery occlusion cannot be explained by… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Dong-Eog Kim from Dongguk University Ilsan Hospital, now live on stage! 💬 We look forward to Dong-Eog Kim 's talk:"Cerebral infarction as a threshold-sensitive network failure: NAIM as an in vivo platform for mechanism-based drug repurposing in ischemic stroke" 111
ScienceOpen @scienceopen.bsky.social · 25/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comFrom Patient-Specific Networks to Actionable Drug Repurposing Strategies through Multi-Omics Data Integration<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d18425570e83">The increasing availability of multi-omic data offers unprecedented opportunities to characterize… 000
ScienceOpen @scienceopen.bsky.social · 25/09/2026#RExPO26Live #RExPO26 We welcome Nurcan Tuncbag from Koç University, now live on stage! 💬 We look forward to Nurcan Tuncbag's talk: "From Patient-Specific Networks to Actionable Drug Repurposing Strategies through Multi-Omics Data Integration" 📢 Thank you to everyone joining us! 111
ScienceOpen @scienceopen.bsky.social · 24/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comWhat Is Disease?<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d8427091e77">The question of what causes disease has been a challenge since ancient times. Applying the… 001
ScienceOpen @scienceopen.bsky.social · 24/09/2026#RExPO26Live #RExPO26 We welcome Joseph Loscalzo from Harvard Medical School, now live on stage! 💬 We look forward to Joseph Loscalzo's honorary lecture: "What Is Disease?" 📢 Thank you to everyone joining us! 121
ScienceOpen @scienceopen.bsky.social · 24/09/2026 📢 Thank you to everyone joining us! 🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comIntegrating Public Health into Drug Repurposing Ecosystems: A Conceptual Framework from the RePo-SUDOE Project<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d18395080e172"><b>Background </b>Drug repurposing can accelerate therapeutic innovation, but translation remains… 000
ScienceOpen @scienceopen.bsky.social · 24/09/2026#RExPO26Live #RExPO26 We welcome João José Joaquim from Portuguese Society of Public Health, now live on stage! 💬 We look forward to João José Joaquim's talk: "Integrating Public Health into Drug Repurposing Ecosystems: A Conceptual Framework from the RePo-SUDOE Project" 100
ScienceOpen @scienceopen.bsky.social · 24/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comClinical Trials in Drug Repurposing: An Ethics-by-Design Approach<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d18478674e103">Drug repurposing (DR) offers a cost-effective and expedited alternative to de novo drug discovery.… 000
ScienceOpen @scienceopen.bsky.social · 24/09/2026#RExPO26Live #RExPO26 We welcome Filipa Lopes from University of Porto, now live on stage! 💬 We look forward to Filipa Lopes's talk: "Clinical Trials in Drug Repurposing: An Ethics-by-Design Approach" 📢 Thank you to everyone joining us! 110
ScienceOpen @scienceopen.bsky.social · 24/09/2026🔗Abstract drugrepocentral.scienceopen.com/hosted-docum...drugrepocentral.scienceopen.comFrom Off-Label Evidence to Authorised Care: Mapping Europe’s Article 48 Drug Repurposing Pipeline<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d7578918e95">Drug repurposing is usually framed as a discovery problem: identify new mechanisms, validate… 000