The idea that universes evolve like organisms sat on the fringes of theoretical physics for decades. Then, a Substack post and a 2022 find by the James Webb Space Telescope boosted the concept

DRAGEN rapidly identifies diverse types of genetic variants.

Madrer et al. identify a Parkinson’s disease–specific increase in transfer RNA (tRNA) fragments in human blood, cerebrospinal fluid and postmortem brain tissue, demonstrating the ability of blood-base...

Genome sequencing in newborns is delivering insights into severe genetic diseases not afforded by traditional tests, but integrating genomics into newborn screening remains a logistics and cost challe...

Background Clinical interpretation of genetic variants in the context of the patient’s phenotype is becoming the largest component of cost and time expenditure for genome-based diagnosis of rare genet...

Although antigen cross-presentation is important for DCs to orchestrate anti-tumor CD8+ T cell responses, the role of alternative antigen presentation pathways is unclear. MacNabb et al. show that CD8+ T cell priming can be mediated by DCs that acquire and present tumor-derived MHC-I complexes—a phenomenon known as MHC cross-dressing.

Identifying immunogenic cancer neoantigens for cancer vaccine design is challenging. The authors uncover NOPs as a widespread source of neoantigens derived from structural genomic variants and indels....

Description of my issues with chatGPT translating data from Wikipedia into SQL. I detected halucinations, which could be harmful in other areas.

The Cancer Dependency Map (DepMap) is a data repository and research platform that can be utilized to systematically identify cancer vulnerabilities. Here Arafeh, Shibue et al. outline the current lim...