Our paper has now been published in Nature Communications!
nature.com/articles/s41...
We found that the tight junction protein ZO-1 translocates to podosomes upon ERK activation and promotes invasive cell migration.
We hope you find our work interesting!
nature.com
ZO-1 shuttles between apical junctional complexes and podosomes by riding ERK activation waves - Nature Communications
This study shows that a junction protein, ZO-1, moves within migrating cells in response to ERK signaling waves, helping coordinate cell movement and promote invasion, revealing how cells integrate si...