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Sayuki Hirano

@sayukihirano.bsky.social
35 followers 14 following 2 posts

Assistant Professor in Kyoto University

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Sayuki Hirano @sayukihirano.bsky.social · 17/07/2026
Our paper has now been published in Nature Communications! nature.com/articles/s41... We found that the tight junction protein ZO-1 translocates to podosomes upon ERK activation and promotes invasive cell migration. We hope you find our work interesting!
nature.com
ZO-1 shuttles between apical junctional complexes and podosomes by riding ERK activation waves - Nature Communications
This study shows that a junction protein, ZO-1, moves within migrating cells in response to ERK signaling waves, helping coordinate cell movement and promote invasion, revealing how cells integrate si...
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Reposted by Sayuki Hirano
Lucien Hinderling @lhinderling.bsky.social · 18/12/2025
Tracking coordinated cellular dynamics directly from images -- New method paper by labmates @bgraedel.bsky.social & @macdobry.bsky.social ! Python package & @napari.org plugin, all the good stuff: Paper: doi.org/10.1242/jcs.... Code: github.com/pertzlab/arc... Plugin: github.com/pertzlab/arc...
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Reposted by Sayuki Hirano
bioRxivpreprint @biorxivpreprint.bsky.social · 09/08/2024
ZO-1 shuttles between tight junctions and podosomes by riding ERK activation waves during collective cell migration www.biorxiv.org/content/10.1101/202…
biorxiv.org
ZO-1 shuttles between tight junctions and podosomes by riding ERK activation waves during collective cell migration https://www.biorxiv.org/content/10.1101/2024.08.09.607278v1
Collective cell migration is essential in various physiological processes, including embryonic devel
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