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Reposted by Sarah Orr

Sarah Rice @grainofscience.bsky.social · 06/12/2024

Our @DiMeN_DTP student @saraheorr.bsky.social giving a really clear overview of the work she has been busy analysing over the last year. Presented at the CIMA/CMAR joint meeting in Nottingham. Well done Sarah! Happy to capture Eugene’s amazing jumper in the shot 📸

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Reposted by Sarah Orr

Sarah Rice @grainofscience.bsky.social · 22/11/2024

Here it is! The first paper from my lab is out today in #AJHG In brief, we quantified the changing methylome through a large window of prenatal human articular cartilage development and identified methylation QTLs co-localising with 24 OA risk signals www.cell.com/ajhg/fulltex...

cell.com

The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk

Emerging evidence supports developmental factors impacting osteoarthritis risk in older age. Here, we quantify the methylome of 72 human fetal knee cartilage samples and identify 24 independent osteoa...

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Reposted by Sarah Orr

Sarah Rice @grainofscience.bsky.social · 14/11/2024

We are advertising a fully funded PhD project starting September 2025. We’ve been excited for this for a long time- biologically unravelling the results of genetic studies to understand the mechanism of cartilage breakdown conferred by SNPs. Reach out if interested! www.findaphd.com/phds/project...

findaphd.com

MRC DiMeN Doctoral Training Partnership: Investigating the role of COLGALT2 in osteoarthritis using a stem cell model of cartilage health and disease at Newcastle University on FindAPhD.com

PhD Project - MRC DiMeN Doctoral Training Partnership: Investigating the role of COLGALT2 in osteoarthritis using a stem cell model of cartilage health and disease at Newcastle University, listed on F...

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