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Sandra Nitsch

@sandrani.bsky.social

57 followers 116 following 6 posts

Postdoc in Robert Schneider’s lab at Helmholtz Munich. Into histone acylations and coffee.

Posts Replies Media

Sandra Nitsch @sandrani.bsky.social · 23/12/2025

So great to finally see this work out ✨ thanks to everyone involved over the years!

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Sandra Nitsch @sandrani.bsky.social · 23/12/2025

Thanks a lot, Ana :)

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Sandra Nitsch @sandrani.bsky.social · 23/12/2025

And just like these acylations acting in concert rather than independently, this work was a massive team effort 💪 Huge thanks to all the amazing collaborators, co-authors and friends!!! 🧵 3/3

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Sandra Nitsch @sandrani.bsky.social · 23/12/2025

We took a closer 👀 at H4K16 acylations: From in vitro assays to in vivo metabolic disease models! These acylations modulate inter- & intranucleosomal interactions and provide resilience to metabolic challenges. 🧵2/3

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Sandra Nitsch @sandrani.bsky.social · 23/12/2025

Paper alert 🚨 Are you interested in the connection between epigenetics and metabolism? Then check out our new paper 🎁 👉 www.sciencedirect.com/science/arti... 🧵1/3

sciencedirect.com

H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations

Histone modifications play crucial roles in genome function. However, how chromatin integrates physiological and metabolic responses at the molecular …

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Sandra Nitsch @sandrani.bsky.social · 23/12/2025

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