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Sandra O. Tomé @sandraneuropath.bsky.social · 03/12/2024

This new study sought to characterize pure #LATE-NC using data from 32 ADRCs. Importantly, it suggests that pure LATE-NC occurs in about 5% of the elderly population, and is usually associated with #dementia. 🧠🔬 link.springer.com/article/10.1...

link.springer.com

Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer’s pathologies - Acta Neuropathologica

Pure limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes (pure LATE-NC) is a term used to describe brains with LATE-NC but lacking intermediate or severe levels of Alzheimer’s...

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