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Johan K. Sandberg

@sandbergjk.bsky.social
21 followers 23 following 10 posts

Scientist

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Johan K. Sandberg @sandbergjk.bsky.social · 17/09/2026
Happy to share our recent findings on the role of MAIT cells in the immunopathogenesis of Staphylococcus aureus infection resulting from the excellent work by Elisa Raineri in my lab: journals.asm.org/doi/10.1128/...
journals.asm.org
MAIT cell responses to Staphylococcus aureus and sensitivity to HlgAB toxin are modulated by activation and tissue-dependent virulence effects | mBio
Mucosa-associated invariant T (MAIT) cells are an evolutionarily conserved unconventional T cell subset that responds to riboflavin pathway-derived antigens from a range of microbes. Here, we found th...
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Johan K. Sandberg @sandbergjk.bsky.social · 28/01/2026
Pleased to share new work from us showing effects of elexacaftor/tezacaftor/ivacaftor (ETI) therapy on the function and quality of the T cell compartment in people with cystic fibrosis, both in the airways and systemically. @ki.se #cysticfibrosis #Tcells #MAIT rdcu.be/e06Rw
rdcu.be
Systemic and airway T cell dynamics with influenza-specific immune recovery by cystic fibrosis elexacaftor/tezacaftor/ivacaftor therapy
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Reposted by Johan K. Sandberg
Edwin Leeansyah @eleeansyah.bsky.social · 26/11/2025
New preprint from the lab on our continuing work on #MAIT cells in #AMR! Fantastic collaboration with Duke-NUS & @sandbergjk.bsky.social @ki.se
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Johan K. Sandberg @sandbergjk.bsky.social · 06/10/2025
Absolutely fantastic to see important discoveries about central immunology principles of self-tolerance being recognized this year! www.nobelprize.org/prizes/medic...
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Johan K. Sandberg @sandbergjk.bsky.social · 28/07/2025
Pleased to share our latest paper providing new insights regarding the human MAIT cell response to gastrointestinal bacterial infection (ETEC). @ki.se academic.oup.com/jimmunol/adv...
academic.oup.com
The MAIT cell response to controlled oral enterotoxigenic E. coli challenge
Abstract. Mucosal-associated invariant T (MAIT) cells recognize conserved microbial antigens presented by the non-polymorphic MR1 molecules and play import
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Johan K. Sandberg @sandbergjk.bsky.social · 21/07/2025
Happy to share this new study on the influence of tissue localization and antigen specificity on human CD8 T cell expression of cytolytic effector functions. My lab at @ki.se proudly contributed: www.science.org/doi/10.1126/...
science.org
Tissue origin and virus specificity shape human CD8+ T cell cytotoxicity
Memory CD8+ T cells have differential cytotoxic capacities across human tissues.
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Johan K. Sandberg @sandbergjk.bsky.social · 30/04/2025
Heartfelt congratulations to Professor Emeritus Klas Kärre, with whom I had the pleasure and honor to do my PhD back in the 1990-ies, on the election as an international member of the US National Academy of Sciences. Fantastic choice and great news! @ki.se www.nasonline.org/news/2025-na...
nasonline.org
National Academy of Sciences Elects Members and International Members - NAS
WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 30 international members in recognition of their distinguished and continuing achievements in original res...
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Johan K. Sandberg @sandbergjk.bsky.social · 22/03/2025
Blue skies at Trysil, Norway, today. Fantastic destination for Scandinavian family-friendly skiing. #Norway #Trysil
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Johan K. Sandberg @sandbergjk.bsky.social · 05/02/2025
Good evening Bluesky! This my first message in this forum: Proud to share our latest findings out yesterday in @pnas.org showing how human mucosal-associated invariant T (#MAIT) cells rapidly adapt their functional response profile to cues in the microenvironment www.pnas.org/doi/10.1073/... @ki.se
pnas.org
Human MAIT cell response profiles biased toward IL-17 or IL-10 are distinct effector states directed by the cytokine milieu | PNAS
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that mediate rapid antimicrobial immune responses to antigens derived from m...
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