Excited to share our latest paper! We show that frog proteins bind and functionally neurotoxins involved in paralytic shellfish poisoning, with exciting potential applications in diagnostics and therapies!
www.nature.com/articles/s41...
nature.com
Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins - Nature Communications
Dinoflagellates and cyanobacteria produce saxitoxin (STX) congeners that block voltage-gated sodium channels. Here authors show how amphibians may sequester STX congeners using a ‘lock and key’ mode, ...
