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Sam Centanni

@samcentanni.bsky.social
154 followers 71 following 9 posts

Neuroscience assistant professor at Wake Forest University School of Medicine. Stress/addiction neurocircuitry (www.centannilab.com). Part time 🏒, 🏃🏻‍♂️, 🏌️‍♂️, ⛷️. The views expressed here are my own and do not reflect those of Advocate Health

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Sam Centanni @samcentanni.bsky.social · 27/08/2026
Great feature on grad student Tatiyana Adkins and her recent JNeuro paper. Excellent timing too- Tatiyana was just awarded an F31 NRSA from the NIAAA Very proud of all she’s accomplished and excited to see where the F31 project takes her!
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SfN Journals @sfnjournals.bsky.social · 05/06/2026
#JNeurosci highlight of the week: S1-insula neurons modulate AUD-related behavior. Explore this week’s selection of featured research: www.jneurosci.org/content/featured-…
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Sam Centanni @samcentanni.bsky.social · 04/06/2026
Also incredibly honored that our image was selected as the cover art for this issue. We used viral tracing and whole-brain light sheet microscopy to map the brain-wide collateral targets of primary somatosensory cortex neurons that project to the insula.
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Sam Centanni @samcentanni.bsky.social · 03/06/2026
Really excited to finally have this paper published 🎉🎊. A true team effort spanning many years and multiple lab members. Special thanks to former MS student Amanda Salazar for launching the project and current PhD student Tatiyana Adkins for leading the final push. Proud of everyone who contributed!
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Sam Centanni @samcentanni.bsky.social · 19/02/2026
🚨New lab paper! TL;DR we ID'd interesting connections between alcohol naïve stress-induced insula activity, and negative affect-like behavior in abstinence after chronic alcohol exposure. An AUD susceptibility marker? Congrats to 1st author Ben Williams! www.sciencedirect.com/science/arti...
sciencedirect.com
Association of stress-sensitive mid-insula activity with alcohol drinking and negative affect-like behavior during abstinence in mice
Stress is central to many neuropsychiatric conditions, including alcohol use disorder (AUD). Stress influences alcohol initiation, escalation, progres…
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Sam Centanni @samcentanni.bsky.social · 26/11/2025
Want to combat the Thanksgiving food coma? Grab a cozy spot on the couch and read our new paper in Psychopharmacology, part of an upcoming special issue honoring the late Dr. Klaus Miczek's seminal contributions. Congrats co-first authors Aditi Buch & Ava Shipman! link.springer.com/article/10.1...
link.springer.com
Single prolonged stress in mice: interactions between alcohol drinking, negative affect, and fear learning - Psychopharmacology
Rationale & objective Exposure to traumatic stressors can have detrimental effects on one’s well-being. Alcohol is often used as a coping mechanism to alleviate stress, leading to the development of a...
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Zoe McElligott @nanopharmnc.bsky.social · 02/10/2025
One more week for poster submissions (Due Oct 9!) to #WCBR2026 www.winterbrain.org
winterbrain.org
Winter Conference on Brain Research | WCBR
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Sam Centanni @samcentanni.bsky.social · 23/09/2025
Next big lab news: we’ve received an R01 from the NIAAA to study the role of the insular cortex in stress and alcohol use disorder-related behavior! It’s been a longgg road to get here, but I’m incredibly excited (and grateful) to finally be able to pursue this research
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Sam Centanni @samcentanni.bsky.social · 19/09/2025
All my trainees have been absolutely crushing it lately- receiving awards, submitting manuscripts and grants, giving phenomenal talks, posters, etc. But special shoutout to PhD student Aditi Buch, for receiving an F31 NRSA from NIAAA! Aditi is a rock star and she developed an awesome project.
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Sam Centanni @samcentanni.bsky.social · 19/09/2025
I’ve been quiet here and on the other platform for a while partly to tune out the inescapable negativity. But i'll admit I miss the good side of science social media- celebrating wins and learning about the cool science others are doing. I’ve got some exciting lab updates to share. Stay tuned!
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Jeff Weiner @jlweiner.bsky.social · 05/02/2025
The CSR comm I'm on just pulled all Diversity F grants from the current review cycle. These apps are reviewed alongside (and by the same criteria) as all other F grants. So, instead of helping these trainees, they will actually be punished by having their grant reviews delayed at least 1 cycle !?!?
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Nick Petersen @nickpetersen.bsky.social · 13/01/2025
I’m pumped to share that our new paper in Biological Psychiatry is out! We dissected a novel astrocyte-neuron interaction in the ventral periaqueductal gray (vPAG) that maintains wakefulness involving norepinephrine and dopamine neurons🧵: www.biologicalpsychiatryjournal.com/article/S000...
biologicalpsychiatryjournal.com
Adenosine A2A Receptors Link Astrocytic α1-Adrenergic Signaling to Wake-Promoting Dopamine Neurons
Sleep and arousal disorders are common, but the underlying physiology of wakefulness is not fully understood. The locus coeruleus promotes arousal via α1-adrenergic receptor (α1AR)–driven recruitment ...
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Sam Centanni @samcentanni.bsky.social · 08/01/2025
Hello Bluesky! 👋 Excited to join this community. Interested in what the lab is working on? Instead of spending an hour perfecting/overthinking my first post, here's something even better: our lab's very first preprint! Just uploaded to @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
A stress-activated mid-insula to BNST pathway regulates susceptibility to abstinence-induced negative affect in female mice
Stress is central to many neuropsychiatric conditions, including alcohol use disorder (AUD). Stress influences the initiation and continued use of alcohol, the progression to AUD, and relapse. Identif...
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