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Chise

@sailorrooscout.bsky.social
94K followers 756 following 40K posts

Senior Scientist | Vaccine Research & Development | NIH | NIAID | VRC | 🧬🧫🦠🔬💉🥼🥽 | 🏳️‍🌈 | @coralchimera.bsky.social 💍 | @phoenixnest.bsky.social & @multicolorbark.com & @likeapalette.com 🧵🪡

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Reposted by Chise
Chise @sailorrooscout.bsky.social · 09/10/2026
How Vaccines Work 🧬🧫🧪🔬💉🥽
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Reposted by Chise
Chise @sailorrooscout.bsky.social · 07/10/2026
heads up
An anthropomorphic pine marten jumping down
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Chise @sailorrooscout.bsky.social · 18h
Absolutely!
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Chise @sailorrooscout.bsky.social · 22h
Wonderful! ☺️👏
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Chise @sailorrooscout.bsky.social · 22h
It’s not that it’s weaker, it’s that you have to give it time to respond to the vaccine!
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Chise @sailorrooscout.bsky.social · 10/10/2026
and death. Please make sure you are protected and up to date on your vaccinations. You can read all of this and more here: • www.scientificamerican.com/article/see-... • www.cidrap.umn.edu/adult-non-fl... • www.nature.com/articles/d41... • www.who.int/news-room/fe... • www.ncoa.org/article/how-...
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Chise @sailorrooscout.bsky.social · 09/10/2026
I know! 😭
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Chise @sailorrooscout.bsky.social · 09/10/2026
I’m so glad! ☺️
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Chise @sailorrooscout.bsky.social · 09/10/2026
Wonderful! 👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
I’m so glad! ☺️
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Chise @sailorrooscout.bsky.social · 09/10/2026
🤭
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Chise @sailorrooscout.bsky.social · 09/10/2026
Indeed!
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Chise @sailorrooscout.bsky.social · 09/10/2026
🤭
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Chise @sailorrooscout.bsky.social · 09/10/2026
Good! 👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
It’s the best! ☺️👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
So do I!
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Chise @sailorrooscout.bsky.social · 09/10/2026
☺️👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
It’s the best! 🤭
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Chise @sailorrooscout.bsky.social · 09/10/2026
Wonderful! 👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
My pleasure! ☺️
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Chise @sailorrooscout.bsky.social · 09/10/2026
My pleasure! And so glad to hear it! ☺️
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Chise @sailorrooscout.bsky.social · 09/10/2026
🤭
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Chise @sailorrooscout.bsky.social · 09/10/2026
Please do!
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Chise @sailorrooscout.bsky.social · 09/10/2026
☺️👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
☺️👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
Whew! I know that came in handy! I hope you have been doing alright!
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Chise @sailorrooscout.bsky.social · 09/10/2026
Agreed! ☺️👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
I just compose the threads! The animation comes from here! bsky.app/profile/sail...
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Chise @sailorrooscout.bsky.social · 09/10/2026
See within the thread for explanations on different types of vaccines.
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Chise @sailorrooscout.bsky.social · 09/10/2026
It’s so good! 😂👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
this way, the body is trained to fight the specific disease-causing organism, building up memory of the pathogen so as to rapidly fight it if and when exposed in the future. As always, vaccination remains THE key intervention against severe disease, hospitalization,
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Chise @sailorrooscout.bsky.social · 09/10/2026
would have on its first reaction to the actual pathogen. Some vaccines require MULTIPLE doses/boosters given weeks or months apart. THIS IS NORMAL. This is sometimes needed to allow for the production of long-lived antibodies and development of memory cells.
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Chise @sailorrooscout.bsky.social · 09/10/2026
Regardless of whether a vaccine is made up of the antigen itself or the blueprint so that the body will produce the antigen, this weakened version WILL NOT cause the disease in the person receiving the vaccine, but it will prompt their immune system to respond much as it
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Chise @sailorrooscout.bsky.social · 09/10/2026
Of course! ☺️
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Chise @sailorrooscout.bsky.social · 09/10/2026
viral components that make up the virus itself. Again, the mRNA vaccines do not contain any virus, so you cannot get a virus from the vaccine. The protein that helps your immune system recognize and fight the virus DOES NOT cause infection of any sort.
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Chise @sailorrooscout.bsky.social · 09/10/2026
mRNA vaccines instruct your cells to reproduce a protein that is part of the virus, which helps your body recognize and fight the virus, if it comes along. Note. The protein IS NOT the virus. It’s a protein. It can’t do anything on its own without other
The genetic sequence of the virus spike is used to make a synthetic mRNA sequence - the instructions to make the spike protein
The mRNA is packaged into a naoparticle - the vaccine - which can deliver the mRNA to immune cells
The immune cells follow the mRNA code to produce spike protein, which is displayed on the cell surface. This stimulates an immune response
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Chise @sailorrooscout.bsky.social · 09/10/2026
In reference to the images above, think about why we may call something NOVEL. New Pathogen? Essentially NO antibody. This is where vaccines work. They can help prevent disease. When not enough people get them, diseases CAN return. This is why childhood vaccination is ESPECIALLY important.
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Chise @sailorrooscout.bsky.social · 09/10/2026
So how do vaccines help? Vaccines can contain weakened or inactive parts of a particular organism (antigen) that triggers an immune response within the body. Newer vaccines contain the blueprint for producing antigens rather than the antigen itself.
When a new pathogen or disease enters our body, it introduces a new antigen. For every new antigen, our body needs to build a specific antibody that can grab onto the antigen and defeat the pathogen.A VACCINE is a tiny weakened non-dangerous fragment of the organism and includes parts of the antigen. It's enough that our body can learn to build the specific antibody. Then if the body encounters the real antigen later, as part of the real organism, it already knows how to defeat it.
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Chise @sailorrooscout.bsky.social · 09/10/2026
The Body’s Natural Response (WITH A CAVEAT) ⬇️
Germs are all around us, both in our environment and in our bodies. When a person is susceptible and they encounter a harmful organism, it can lead to disease and death.
The body has many ways of defending itself against pathogens (disease-causing organisms). Skin, mucus, and cilia (microscopic hairs that move debris away from the lungs) all work as physical barriers to prevent pathogens from entering the body in the first place.
When a pathogen does infect the body, our body's defences, called the immune system, are triggered and the pathogen is attacked and destroyed or overcome.
If you aren't aware, a pathogen is a bacterium, virus, parasite or fungus that can cause disease within the body. Each pathogen is made up of several subparts, usually unique to that specific pathogen and the disease it causes. The subpart of a pathogen that causes the formation of antibodies is called an antigen.
The antibodies produced in response to the pathogen's antigen are an important part of the immune system. You can consider antibodies as the soldiers in your body's defense system. Each antibody, or soldier, in our system is trained to recognize one specific antigen. We have thousands of different antibodies in our bodies. When the human body is exposed to an antigen for the first time, it takes time for the immune system to respond and produce antibodies specific to that antigen.The antibodies produced in response to the pathogen's antigen are an important part of the immune system. You can consider antibodies as the soldiers in your body's defense system. Each antibody, or soldier, in our system is trained to recognize one specific antigen. We have thousands of different antibodies in our bodies. When the human body is exposed to an antigen for the first time, it takes time for the immune system to respond and produce antibodies specific to that antigen.
In the meantime, the person is susceptible to becoming ill.
Once the antigen-specific antibodies are produced, they work with the rest of the immune system to destroy the pathogen and stop the disease. Antibodies to one pathogen generally don't protect against another pathogen except when two pathogens are very similar to each other, like cousins. Once the body produces antibodies in its primary response to an antigen, it also creates antibody-producing memory cells, which remain alive even after the pathogen is defeated by the antibodies. If the body is exposed to the same pathogen more than once, the antibody response is much faster and more effective than the first time around because the memory cells are at the ready to pump out antibodies against that antigen.
This means that if the person is exposed to the dangerous pathogen in the future, their immune system will be able to respond immediately, protecting against disease.
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Chise @sailorrooscout.bsky.social · 09/10/2026
I know I posted this information in a previous thread of mine but because it’s getting close to booster season I wanted to put that same information on this thread as well just in case someone missed the previous thread!
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Chise @sailorrooscout.bsky.social · 09/10/2026
And should you need it. You can find vaccines near you using this website. Stay healthy and protected. Search for vaccine locations in your area and schedule your appointment today. • vaccinefinder.org
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Chise @sailorrooscout.bsky.social · 09/10/2026
You can read more on that here: • www.nature.com/articles/d41... • www.nejm.org/doi/full/10....
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Chise @sailorrooscout.bsky.social · 09/10/2026
The vaccine is also being reviewed by regulatory agencies in the European Union, Canada and Australia. A related product has already been permitted for use in Europe: in April, the European Commission approved Moderna’s combined seasonal influenza and COVID-19 mRNA vaccine mCombriax.
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Chise @sailorrooscout.bsky.social · 09/10/2026
Researchers welcomed the decision, noting that the vaccine’s mRNA platform allows it to be rapidly reformulated to match circulating influenza strains. Flu IS showing up earlier this year so consider getting your vaccine soon if you haven’t already! • www.axios.com/2026/10/09/f...
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Chise @sailorrooscout.bsky.social · 09/10/2026
Last month, the FDA granted approval to Moderna’s mRNA-based flu vaccine, mFLUSIVA, for adults aged 50–64, and accelerated approval for adults aged 65 and older. It is NOW available for the 2026–27 flu season.
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Chise @sailorrooscout.bsky.social · 09/10/2026
I’m so glad! It’s always a good reminder! ☺️👏
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Chise @sailorrooscout.bsky.social · 09/10/2026
The composition was decided back in May in case you missed it: • www.cidrap.umn.edu/covid-19/fda... • www.cidrap.umn.edu/adult-non-fl... ALL COVID VACCINES THIS YEAR (mRNA and non-mRNA) are the SAME COMPOSITION.
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Chise @sailorrooscout.bsky.social · 09/10/2026
CVS also has updated COVID vaccines for the 2026-2027 season available. Appointments are open for the updated vaccine so be sure to check your local pharmacy. • www.cvs.com/immunization...
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Chise @sailorrooscout.bsky.social · 09/10/2026
For those of you wondering about the 2026-2027 COVID-19 vaccines. THEY ARE AVAILABLE NOW AT WALGREENS. The 2026-2027 COVID-19 vaccine composition has been designed to match the JN.1-lineage XFG variant for the upcoming respiratory season. • www.walgreens.com/topic/promot...
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Chise @sailorrooscout.bsky.social · 09/10/2026
Especially right now! 👏
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