Nature Reviews Disease Primers - This Primer by Sahin and colleagues summarizes the epidemiology, pathophysiology, diagnosis and treatment of tuberous sclerosis complex.

This work introduces an open-source all-optical platform for functional phenotyping of human stem cell-derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and...

Molecular Psychiatry - Phenotypic rescue via mTOR inhibition in neuron-specific Pten knockout mice reveals AKT and mTORC1-site specific changes

A study in a mouse model of obesity and prediabetes demonstrates that recruitment of macrophages to nerves has a protective role in diet-induced peripheral neuropathy.