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Sergio Gutiérrez

@sagutierrezz.bsky.social
57 followers 67 following 6 posts

Associate Researcher in Synthetic Genomics at UoM | Metabolic engineering | Synthetic Biology | Scientific Illustrator & Photographer enthusiast

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Sergio Gutiérrez @sagutierrezz.bsky.social · 10/08/2026
Happy to see our Journal Club piece out in @natureportfolio.nature.com where we look at how ‘recombitrons’ can push precise genome editing across bacterial diversity, while also asking what actually makes an editing tool portable across species? rdcu.be/fyYIY
rdcu.be
Recombitrons enable bacterial genome editing across phyla
Nature Microbiology - Recombitrons enable bacterial genome editing across phyla
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Sergio Gutiérrez @sagutierrezz.bsky.social · 02/06/2025
We’ll build synthetic chromosomes for plants with new stress tolerance and nutrient traits. At Cai Lab, we’re rewiring DNA for more resilient, higher-value organisms. www.manchester.ac.uk/about/news/f...
manchester.ac.uk
improving crop resilience and nutritional value
A new project, co-led by Dr Joshua James and Professor Patrick Cai of the Manchester Institute of Biotechnology at The University of Manchester, in collaboration with the John Innes Centre and Earlham...
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Reposted by Sergio Gutiérrez
Gherman Novakovsky @gnovakovsky.bsky.social · 30/05/2025
Excited to share my first contribution here at Illumina! We developed PromoterAI, a deep neural network that accurately identifies non-coding promoter variants that disrupt gene expression.🧵 (1/)
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Sergio Gutiérrez @sagutierrezz.bsky.social · 10/03/2025
👀 On the cover. Building on our agarwood sesquiterpenoid recreation approach, this shows how photosynthetic machinery can drive P450-mediated functionalization – another step toward sustainable production of terpenes. shorturl.at/ge3lX #GreenChemistry #synbio #algae
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Sergio Gutiérrez @sagutierrezz.bsky.social · 30/01/2025
Today, James not only defended his PhD in genetic code expansion with precision but has been teaching me fascinating scientific insights throughout our work together. Proud to witness his academic milestone. 🧬 #SyntheticBiology #PhDSuccess
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Sergio Gutiérrez @sagutierrezz.bsky.social · 13/12/2024
2011: Colombian kid dreams of being a surgeon 2024: PhD Bioengineering, from fighting superbugs to engineering microalgae to synthetic genomes 8 years, 3 degrees, 3 continents, 4 amazing mentors, countless experiments later. From Colombia to Saudi Arabia to the United Kingdom. #Latin #Scientist
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Sergio Gutiérrez @sagutierrezz.bsky.social · 05/12/2024
🧪 Final PhD paper published! We compartmentalized sesquiterpenoid biosynthesis in algal chloroplasts, using photosynthetic electrons to drive P450-mediated oxidation without reductase partners. #algae #synbio #terpenoids chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com
Compartmentalized Sesquiterpenoid Biosynthesis and Functionalization in the Chlamydomonas reinhardtii Plastid
Photosynthetic microalgae were engineered for compartmentalized sesquiterpenoid biosynthesis by targeting synthases and cytochrome P450s to the chloroplast. The plastid's electron transport chain dri...
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