Saad Nagi @saadsnagi.bsky.social · 21/08/2026Delighted to see this work from Max Larsson and colleagues now published! Grateful to have contributed the human side of the story. Special mention to Oumie Thorell for leading our experiments, and to IW for his generous participation and longstanding contributions to neuroscience. 030
Reposted by Saad NagiMarcin Szczot @szczotml.bsky.social · 14/12/2025Not all pain is created equal: stepping on a nail feels different from a stomachache. We know there are many nociceptor types, but a key question remains: how is mechanical pain encoded across the body by those sensory neurons? Our new work helps answer this. 1/8 www.biorxiv.org/content/10.6...biorxiv.orgHierarchical organization of mechano-nociceptive pathways revealed by activity labelingNoxious mechanical stimuli give rise to distinct percepts, from sharp cutaneous pain to diffuse visceral discomfort, yet the nociceptor ensembles that underlie these differences remain poorly defined.... 22414
Reposted by Saad NagiAngelika Lampert @lampertlab.bsky.social · 16/04/2025It will be turbulent in the next worldwide sodium channel seminar: @antoniospantazis.bsky.social will explain why "Even a single carbon atom matters: deadly and unexpected consequences of a Nav1.5 variant" Tuesday April 29th. Visit www.sodiumchannelseminars.org for link and infos. #sodiumchannel 044
Saad Nagi @saadsnagi.bsky.social · 12/01/2025Nice writeup on our latest work by NIH Research Matters: Characterizing What Human Sensory Nerves Can Sense! www.nih.gov/news-events/...nih.govCharacterizing what human sensory nerves can senseResearchers analyzed gene activity in different human sensory nerve cells to predict which would respond to stimuli such as heat, cold, and pressure 043