Reposted by Riccardo Rozza
Curious about how GTP hydrolysis occurs in small Rho GTPases? Check out our newly published JACS article!
@jacs.acspublications.org Excellent work by @angelaparis3.bsky.social @rrozza.bsky.social
pubs.acs.org/doi/abs/10.1...
pubs.acs.org
Glutamine Tautomerization Drives RhoGAP-Aided GTP Hydrolysis in Small Rho GTPases
Rho GTPases promote GTP hydrolysis aided by specific GTPase-activating proteins (GAPs). By alternating between an active GTP-bound and an inactive GDP-bound state, Rho GTPases function as molecular sw...
