iiinova — where your digital self keeps evolving

Sergio Romero² @romeritos.bsky.social · 19/03/2025

Thrilled to share that my former student, Alex Braun, has been awarded the Rainer Rudolph Prize 2024 for his master's thesis on designing artificial enzymes with language models! Immensely proud of him. A toast all the way from Mexico! 🎉👏🌟 Preprint: www.biorxiv.org/content/10.1...

010

Sergio Romero² @romeritos.bsky.social · 19/03/2025

How does collagen fold? Very carefully! (And with some help from electrostatics.) Our latest collaborative study uncovers kinetic mechanisms where interchain electrostatic interactions act as molecular clamps to promote proper folding. Check it out! 🎉🌟🧬🧫 www.nature.com/articles/s41...

nature.com

Deciphering the folding code of collagens - Nature Communications

Collagen triple helices are found in all the three domains of life as well as viruses. Here, the authors show that collagens have converged on a similar folding mechanism that employs salt bridge...

031

Reposted by Sergio Romero²

Daniel Ríos @yosoyden.bsky.social · 17/03/2025

The first original research paper from my lab is now out in @biorxivpreprint.bsky.social! www.biorxiv.org/content/10.1... Tracheal development is an amazing model to study morphogenesis. There are great works out there that show how this tissue elongates, interconnects, and forms branches (1/n)

biorxiv.org

Adhesion to a common ECM mediates interdependence in tissue morphogenesis in Drosophila

For organs to be functional, the cells and tissues that constitute them must effectively interact with each other and coordinate their behaviours. Halfway during Drosophila embryogenesis, two lateral ...

2298