iiinova — where your digital self keeps evolving

Robert Lufkin MD @robertlufkinmd.bsky.social · 20h

New in Sleep Medicine: a nap experiment with a narrow but useful result. (1/5)

Robert Lufkin MD @robertlufkinmd.bsky.social · 21h

Are driverless cars the decade's biggest public health advance? 39k US traffic deaths in 2024. Waymo study (56.7M miles): 79% lower injury-crash rate vs humans — promising signal, not a finished safety case. www.tandfonline.com/doi/full/10....

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Robert Lufkin MD @robertlufkinmd.bsky.social · 21h

What does a falling inflammation marker actually tell us? A prespecified analysis of the 17,604-person SELECT randomized trial studied adults with established cardiovascular disease and overweight or obesity, without diabetes ([Circulation](pubmed.ncbi.nlm.nih.gov/42610271/)). (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 22h

Promising is not the same as proven. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 23h

Floss tonight. Daily flossing tracked with lower CVD-event odds and CVD mortality in a large NHANES analysis (observational). Educational tip only.

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Robert Lufkin MD @robertlufkinmd.bsky.social · 23h

Lies I Taught in Medical School just won the National Indie Excellence Awards in Health. www.robertlufkinmd.com/lies/

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Robert Lufkin MD @robertlufkinmd.bsky.social · 23h

Hi! I'm Dr. Robert Lufkin, physician, researcher, professor, author, and lifelong student of healthy aging. 200+ scientific publications New York Times bestselling author of Lies I Taught in Medical School 1.2M+ people reached weekly through digital media Featured in the new aging documentary Forev

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Robert Lufkin MD @robertlufkinmd.bsky.social · 04/10/2026

New in The American Journal of Clinical Nutrition: nourishment, not restriction, was the target. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 04/10/2026

The hardest workout is not automatically the best-supported choice. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 04/10/2026

Topical Rapamycin: Skin Cells Reset to Age 20? Full episode: youtu.be/h3_HepIDmI4

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Robert Lufkin MD @robertlufkinmd.bsky.social · 04/10/2026

What if better glucose control starts with how we train doctors? (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 04/10/2026

Eat beets today. Kapil 2015 RCT: beetroot nitrate juice lowered clinic/home/24h BP over 4 weeks in hypertension. Educational only. Not medical advice. Podcast: Doctor's Daily Drop

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Robert Lufkin MD @robertlufkinmd.bsky.social · 03/10/2026

New in GeroScience: a study of 132 identical-twin pairs followed over roughly 12 years found that better dietary-guideline scores were associated with younger aging-clock readings in some individual-level analyses. (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 03/10/2026

Wikipedia calls me an American LinkedIn celebrity. Grokipedia calls me a physician and professor working on imaging, longevity, and metabolic health. Which version do you like better? en.wikipedia.org/wiki/Robert_... grokipedia.com/page/robert_...

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Robert Lufkin MD @robertlufkinmd.bsky.social · 03/10/2026

Can a supplement improve one cholesterol measure without lowering cholesterol? In a randomized, double-blind crossover trial, 35 healthy adults took 1,500 mg of ginger daily or placebo for six weeks each. (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 03/10/2026

3 Facial Signs of Your True Biological Age Full episode: youtu.be/h3_HepIDmI4

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Robert Lufkin MD @robertlufkinmd.bsky.social · 03/10/2026

29.9% versus 9.5%: that was MASH resolution without worsening fibrosis with resmetirom 100 mg versus placebo at 52 weeks, in a new analysis of 917 patients with moderate-to-advanced liver fibrosis ([trial analysis](pubmed.ncbi.nlm.nih.gov/42527732/)). (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 03/10/2026

Drink green tea today. Ohsaki / JAMA 2006: more green tea, lower mortality signals (observational). Unsweetened cups today. Educational only. Not medical advice.

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Robert Lufkin MD @robertlufkinmd.bsky.social · 02/10/2026

New in Nature: researchers mapped gene activity in more than 1.3 million cell nuclei from 284 donated human brains. (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 02/10/2026

Can a weight-loss plan ignore sleep? (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 02/10/2026

Botox Can Thin Your Jawbone — Permanently Full episode: youtu.be/h3_HepIDmI4

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Robert Lufkin MD @robertlufkinmd.bsky.social · 02/10/2026

A lower number on the scale is not the same as better fitness. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 02/10/2026

Ask for an hs-CRP today. Educational only. Not medical advice.

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Robert Lufkin MD @robertlufkinmd.bsky.social · 01/10/2026

New in NEJM: two phase 3 randomized placebo-controlled trials tested oveporexton in 273 people with narcolepsy type 1. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 01/10/2026

Does newer insulin always mean better glucose control? (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 01/10/2026

Is Retin-A Aging Your Skin Faster? Full: youtu.be/h3_HepIDmI4

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Robert Lufkin MD @robertlufkinmd.bsky.social · 01/10/2026

A protein scoop is not a strength-training program. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 01/10/2026

Skip alcohol tonight. Educational only. Not medical advice.

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Robert Lufkin MD @robertlufkinmd.bsky.social · 01/10/2026

Exercise nearly froze biological aging. In one year, the control group aged nearly 10 months on an epigenetic clock. The exercise group aged about one month. robertlufkinmd.substack.com/p/exercise-n...

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Robert Lufkin MD @robertlufkinmd.bsky.social · 01/10/2026

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Robert Lufkin MD @robertlufkinmd.bsky.social · 30/09/2026

BPC-157: The Real Evidence Is Under 10 Patients. Full: youtu.be/h3_HepIDmI4

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Robert Lufkin MD @robertlufkinmd.bsky.social · 30/09/2026

Skip late-night eating tonight. Educational only. Not medical advice.

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Robert Lufkin MD @robertlufkinmd.bsky.social · 29/09/2026

New in Nature Biotechnology: six protein-based aging clocks predicted lower biological age in treated groups from a 12-week rentosertib trial in idiopathic pulmonary fibrosis ([study](pubmed.ncbi.nlm.nih.gov/42706338/)). (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 29/09/2026

41% versus 10%: the average reduction in daily cornstarch intake with investigational DTX401 gene therapy versus placebo at 48 weeks in a randomized trial of 46 people with glycogen storage disease type Ia ([trial](pubmed.ncbi.nlm.nih.gov/42674977/)). (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 29/09/2026

MRI Proof: Ozempic Attacks Your Facial Fat. Full: youtu.be/h3_HepIDmI4

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Robert Lufkin MD @robertlufkinmd.bsky.social · 29/09/2026

Can exercise cancel the glucose changes that follow a long fast? (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 29/09/2026

Add walnuts. Educational only. Not medical advice.

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Robert Lufkin MD @robertlufkinmd.bsky.social · 28/09/2026

Can a cell-growth signal become too strong for the heart? (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 28/09/2026

New in Science: an AI model learned from more than 400,000 abdominal CT exams, then helped radiologists detect findings more sensitively in a reader study involving 26 doctors ([RADAR study](pubmed.ncbi.nlm.nih.gov/42752131/)). (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 28/09/2026

Plastic Surgeon: Don't Donate Your Face. Full: youtu.be/LlpeKNVy8Mo

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Robert Lufkin MD @robertlufkinmd.bsky.social · 28/09/2026

142,250 participants. Three annual screening rounds. (1/6)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 28/09/2026

Eat berries today. Blueberries or strawberries — fresh or frozen. Educational tip. Not medical advice.

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Robert Lufkin MD @robertlufkinmd.bsky.social · 27/09/2026

A "brain-healthy" diet is not a dementia guarantee. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 27/09/2026

New in Nature Medicine: a liver-fat result worth watching. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 27/09/2026

Can lifting heavier help both muscle and bone around menopause? (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 26/09/2026

In EBioMedicine: a brain-related biomarker improved, but cognition did not show a treatment benefit ([DHA trial](pubmed.ncbi.nlm.nih.gov/42315445/)). (1/4)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 26/09/2026

Exercise does not always make you eat back what you burned. (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 26/09/2026

Nobel Laureate Says AI Could End All Disease Within a Decade. Full: youtu.be/xlcVRLmuF_I

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Robert Lufkin MD @robertlufkinmd.bsky.social · 26/09/2026

What if better heart-failure care included the meals people can actually access? (1/5)

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Robert Lufkin MD @robertlufkinmd.bsky.social · 25/09/2026

Ask Dr. Rob is open. Monthly live Q&A — you send questions ahead, I answer carefully. First show Wed Nov 4, 5pm PT. Join: robertlufkinmd.substack.com/p/introducin...

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