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Ry Lanham

@rlanham1963.bsky.social
425 followers 1.2K following 605 posts

Technological change and acceleration... especially AI and medicine.

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Ry Lanham @rlanham1963.bsky.social · 11/09/2026
Will AI soon lead to double-digit growth? aleximas.substack.com/p/will-ai-so...
aleximas.substack.com
Will AI soon lead to double-digit growth?
Probably not. Here is why.
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Ry Lanham @rlanham1963.bsky.social · 07/09/2026
Early Data Indicates an A.I.-Generated Drug Could Slow Aging www.nytimes.com/2026/09/07/s...
nytimes.com
Early Data Indicates an A.I.-Generated Drug Could Slow Aging
Artificial intelligence was used to help develop a drug candidate, rentosertib, for a rare lung condition. Its maker says the drug also seems to reduce the biological hallmarks of age.
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Ry Lanham @rlanham1963.bsky.social · 31/08/2026
Staggering 90% of biomedical papers now show signs of AI help www.nature.com/articles/d41...
nature.com
Staggering 90% of biomedical papers now show signs of AI help
The figure, which is much higher than previous estimates of large-language-model use, is for papers published in December and archived in PubMed.
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Ry Lanham @rlanham1963.bsky.social · 12/08/2026
I support Wikipedia, where information is still human-created, fact-checked, and 100% free. Join me! donate.wikimedia.org
donate.wikimedia.org
Make your donation now - Wikimedia Foundation
Donate to the Wikimedia Foundation, the nonprofit that hosts Wikipedia and other crucial free knowledge projects. Each year, the generosity of the 2% of readers who donate allows us to expand the reac...
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Ry Lanham @rlanham1963.bsky.social · 28/07/2026
Consciousness research is having an AI moment. Will the hype help the field? www.nature.com/articles/d41...
nature.com
Consciousness research is having an AI moment. Will the hype help the field?
The idea of AI sentience is drawing more focus to consciousness science. But some researchers aren’t sure that’s a good thing.
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Ry Lanham @rlanham1963.bsky.social · 25/07/2026
Can This New Enzyme Turn Back the Clock in the Human Body? www.nytimes.com/2026/07/24/s...
nytimes.com
Can This New Enzyme Turn Back the Clock in Bodily Tissues?
In a recent study, scientists devised a way of reversing the buildup of compounds that lead to some age-related diseases.
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Ry Lanham @rlanham1963.bsky.social · 25/07/2026
Scientists have exploited a peculiar CRISPR enzyme so that it fights cancer. “It’s a molecular kill switch that recognizes a particular RNA,” says Yang Liu, a molecular biologist at the University of Utah School of Medicine. “This is basically a programmable chemotherapy.”
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Ry Lanham @rlanham1963.bsky.social · 21/07/2026
Jennifer Doudna recently said scientific innovation was still “really in the domain of human beings” and that she wasn’t seeing chatbots come up with brand-new ideas. Now her lab has used AI to push a CRISPR-like gene editor far beyond what evolution had already designed.
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Ry Lanham @rlanham1963.bsky.social · 20/07/2026
From the Transcript: Databricks CEO: "We host open-source models such as Kimi and offer them to our customers. Demand has been so strong that we are running out of GPUs across multiple regions. We nearly exhausted our GPU capacity in Asia.
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Reposted by Ry Lanham
Trending Finance @trending-finance.bsky.social · 20/07/2026
Moscow plunges; Wildberries hit again. #econsky
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Ry Lanham @rlanham1963.bsky.social · 20/07/2026
Since Abraham Lincoln’s assassination in 1865, every President has been alive at the same time as Herbert Hoover.
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Ry Lanham @rlanham1963.bsky.social · 17/07/2026
Just saw Christopher Nolan/Oddysey. It was good-ish. It could have been significantly edited down--we got a LONG director´s cut. Acting was... good. Not great. Matt Damon did a respectable job. The special effects and sea scenes were impressive.
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Ry Lanham @rlanham1963.bsky.social · 16/07/2026
www.nature.com/articles/s41...
nature.com
Reversal of protein chemical aging by enzymatic deglycation - Nature Communications
Advanced glycation end products (AGEs) in proteins, a hallmark of aging, are considered irreversible. Here, authors report the development of CMLase - an enzyme that specifically oxidizes Nε-carboxyme...
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Ry Lanham @rlanham1963.bsky.social · 16/07/2026
medicine.washu.edu/news/mrna-va... Incredible cancer breakthrough.
medicine.washu.edu
mRNA vaccines follow unconventional path to destroy tumors | WashU Medicine
Insight from a study by WashU Medicine researchers in mice could guide next-generation cancer vaccine development.
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Ry Lanham @rlanham1963.bsky.social · 16/07/2026
It is inevitable. Precision mRNA is almost certainly right around the corner for anti-aging, especially. Like it or not, regulated or not, it is going to happen in China and elsewhere.
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Ry Lanham @rlanham1963.bsky.social · 16/07/2026
Odd that so many people don´t like it. It makes me a bit suspicious.
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Ry Lanham @rlanham1963.bsky.social · 16/07/2026
deepmind.google/public-polic... Incredible paper from Google DeepMind. One of the most profound near-term visions on AI yet.
deepmind.google
How AI Agents are transforming scientific discovery
AI agents are starting to reshape science, from proposing novel hypotheses to writing code. Learn what comes next for scientists and policymakers.
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Ry Lanham @rlanham1963.bsky.social · 16/07/2026
In biological or control systems, a ternary representation allows for 3 rather than 2 (binary) states. These can be modelled as +1, 0, and -1. Usually the zero state means ¨ ignored ¨ as with a connection in a (neural) network. In small local LLMs, systems are sometimes configured this way.
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Ry Lanham @rlanham1963.bsky.social · 15/07/2026
Calico (short for the California Life Company) is a biotechnology company focused on the biology of aging and the development of interventions to extend human healthspan and lifespan. Founded in 2013 as a subsidiary of Alphabet Inc. (Google's parent company), it attempts anti-aging moonshots.
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Ry Lanham @rlanham1963.bsky.social · 15/07/2026
One of the most significant AI advancements thus far: A plausible path to RSI: www.weco.ai/blog/first-e...
weco.ai
AIDE²: First Evidence of Recursive Self-Improvement | Weco AI
We ran autoresearch on autoresearch: an outer loop rewriting its own research agent for 100 unattended steps. In eight days it discovered agents that beat our two years of hand-tuning on held-out benc...
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Ry Lanham @rlanham1963.bsky.social · 14/07/2026
AI in Zurich, Switzerland:
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Ry Lanham @rlanham1963.bsky.social · 14/07/2026
There are now over 100 humanoid robotics firms in China.
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Ry Lanham @rlanham1963.bsky.social · 14/07/2026
Anthropic’s CEO says “it cannot possibly be more than a few years before AI is better than humans at essentially everything.” Its executives say the exception will be low-wage jobs in “grounds maintenance” “food and serving,” and “personal service.”
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Ry Lanham @rlanham1963.bsky.social · 14/07/2026
It is not a rational trade. If you want to speculate on Mr. Musk or a hyperfuture in space, by all means buy it. At current valuations (comparable to Apple and Amazon and for a brief time more than them) it is unrealistic and even silly.
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Ry Lanham @rlanham1963.bsky.social · 13/07/2026
The Age of Breakthroughs accelerates when you can simulate vast numbers of potential cascades--this is again likely a quantum computing domain. So, I generally view QC as a necessary step to massive rapid medical advancement.
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Ry Lanham @rlanham1963.bsky.social · 13/07/2026
Evolution by its very nature has cascade effects. All complex systems do. Simplicity can be defined as the absence of the unpredictable. Right now, we run tests to see what happens--clinical trials. This is hugely inefficient.
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Ry Lanham @rlanham1963.bsky.social · 13/07/2026
The fundamental problem of medicine now is cascade effects. In genetics this is called a pleiotropic phenomenon. In short, one thing causes a scattershot of outcomes/events. Quantum computing will be a big help in identifying these. Some may be trivial, but some may be fatal.
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Ry Lanham @rlanham1963.bsky.social · 13/07/2026
In plain language, quantum computing augments AI through superior pattern matching--especially in deep, complex data sets (biology). QC acts as a ¨coprocessor¨ that can ¨solve¨ relationships that current conventional AI or even real world model-type AI (Yann LeCun) can integrate into inferences.
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Ry Lanham @rlanham1963.bsky.social · 13/07/2026
An AI model, by itself, is stateless; it doesn’t remember previous interactions, cannot execute code, and has no access to files or the internet. A harness provides the environment to overcome these limitations by specifically enabling them in an external program. It´s almost a mind/body thing.
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Ry Lanham @rlanham1963.bsky.social · 13/07/2026
In the framework of AI, particularly when discussing AI agents, a harness is the software infrastructure that wraps around an AI model (mostly an LLM) to turn it from a "reasoner" into a "doer." A common shorthand used by engineers is: Agent = Model + Harness. A harness can be general or specific.
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Ry Lanham @rlanham1963.bsky.social · 13/07/2026
Researchers from Google Quantum Al/DeepMind developed an Al system that continuously keeps Google's 105-qubit Willow quantum processor optimized continually. It uses reinforcement learning to monitor quantum error correction and automatically adjust hardware control parameters in real time."
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Ry Lanham @rlanham1963.bsky.social · 12/07/2026
Kobeissi: Nvidia, Micron, Broadcom, and Applied Materials, are now expected to generate a record $430 billion in combined free cash flow (FCF) over the next 12 months. That would be more than TRIPLE the FCF they generated 2 years ago.
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Ry Lanham @rlanham1963.bsky.social · 12/07/2026
From Unusual Whales: In March, Trump said the Iran conflict was easing. Meanwhile, his account bought Lockheed Martin, $LMT After the conflict depleted much of the US THAAD missile stockpile, the Pentagon award LMT a 35 billion contract.
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Ry Lanham @rlanham1963.bsky.social · 12/07/2026
At UC San Diego, surgeons fitted a humanoid robot with laparoscopic tools and teleoperated it through a gallbladder removal on an animal. The results were published in Nature. The machines they challenge cost about $2 million, weigh 1,800 pounds, and need an operating room built around them.
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Ry Lanham @rlanham1963.bsky.social · 12/07/2026
He´s a nazi. Full stop.
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Ry Lanham @rlanham1963.bsky.social · 12/07/2026
OpenAI is taking a terrible reputational beating over this Apple lawsuit story... may be irrecoverable.
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Ry Lanham @rlanham1963.bsky.social · 12/07/2026
NY Times: Last year, three of America’s six winners of science Nobels were born outside the country. In this century, overall, the émigré fraction for U.S. Nobels in physics, chemistry and medicine now stands at 40 percent.
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Ry Lanham @rlanham1963.bsky.social · 11/07/2026
polymathic-ai.org/the_well/ This is the most important trove of free physics data ever released. It has simulation data, fundamental data, etc. and is linked to top universities and government labs. Remarkable. Combined with vast AI, it is a huge leap forward for everyone.
polymathic-ai.org
The Well
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Ry Lanham @rlanham1963.bsky.social · 11/07/2026
The Population Forecasts Are Grim. They’re Still Too Optimistic. www.nytimes.com/2026/07/11/o...
nytimes.com
Opinion | The Population Forecasts Are Grim. They’re Still Too Optimistic.
America is not prepared for population decline.
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Ry Lanham @rlanham1963.bsky.social · 11/07/2026
We need to have a long talk about a world where compensation is not feasible. AI is that world. No one can ¨own¨ any reasonable production value or differentiation especially when agents become increasingly recursively improving (RSI).
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Ry Lanham @rlanham1963.bsky.social · 11/07/2026
There is no model of AI where everyone builds and yet keeps earning. The world simply doesn´t need this sort of hyper-economy. It makes no logical sense and won´t exist. Instead, things will increasingly be done for us, but with no compensation flowing to anyone.
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Ry Lanham @rlanham1963.bsky.social · 10/07/2026
Anthropic’s Claude is named after Claude Shannon, an influential American polymath—a mathematician, electrical engineer, computer scientist, and cryptographer—widely recognized as the "father of information theory." His work was mostly at Bell Labs.
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Ry Lanham @rlanham1963.bsky.social · 10/07/2026
Your cells carry an "epigenome," a set of chemical tags that tell genes when to switch on and off. The epigenome acts as the master controller that tells your genes what to do, where to do it, and when to do it. Manipulating it will likely be the key technology of anti-aging.
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Ry Lanham @rlanham1963.bsky.social · 10/07/2026
Nippon.com: Japan has the second lowest percentage of children (10.8%) among the 37 countries in the world whose populations are 40 million or greater behind South Korea with 10.2%.
nippon.com
nippon.com | 日本情報多言語発信サイト
「nippon.com(ニッポンドットコム)」は海外の方にもっと日本を知ってもらうためのウェブサイト。等身大の日本を7つの言語でお届けします。
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Ry Lanham @rlanham1963.bsky.social · 10/07/2026
The Economist reports that a Russian oligarch is warning of a disaster inside Russia. GDP fell 0.2% in Q1 2026 Interest rates remain around 14.25%, and the budget deficit is growing. Russia has already lost around two thirds of its liquid sovereign wealth fund reserves
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Ry Lanham @rlanham1963.bsky.social · 09/07/2026
A Korean stock starts to trade in ADR form tomorrow on Nasdaq. SK Hynix is not a generic chipmaker they are the undisputed king of HBM, high bandwidth memory which is the most critical component inside every NVIDIA GPU powering the AI revolution. The offering is said to be very oversubscribed.
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Ry Lanham @rlanham1963.bsky.social · 09/07/2026
Technical papers--China now starts to dominate.
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Ry Lanham @rlanham1963.bsky.social · 09/07/2026
AI Futures Project blog.aifutures.org?r=70o7&utm_c...
blog.aifutures.org
AI Futures Project | Daniel Kokotajlo | Substack
Preparing for a world with AGI. Click to read AI Futures Project, by Daniel Kokotajlo, a Substack publication with tens of thousands of subscribers.
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Ry Lanham @rlanham1963.bsky.social · 09/07/2026
One strong and detailed prediction about the near-term (up to 14 years) of AI and social transformation: ai-2027.com
ai-2027.com
AI 2027
A research-backed AI scenario forecast.
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Ry Lanham @rlanham1963.bsky.social · 09/07/2026
www.cell.com/cell/fulltex...
cell.com
Recent advances in Alzheimer’s disease: From molecular mechanisms to therapeutic strategies
Alzheimer’s disease is driven by pathological brain changes that progressively impair memory and cognition, with current treatment options being limited. Advances in early, biomarker-based diagnosis a...
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