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Rija Zaidi

@rijazaidi.bsky.social

60 followers 104 following 3 posts

PhD Student | Computational Cancer Genomics Lab | UCL Cancer Institute W: sites.google.com/view/ccgresearchgr… LinkedIn: uk.linkedin.com/in/rija-zaidi-a5220…

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Rija Zaidi @rijazaidi.bsky.social · 16/12/2024

How much do algorithmic and experimental choices drive the accuracy of reconstructing tumour evolution? In this Cancer Research commentary, @zaccasimo.bsky.social and I discuss a recent Nature Biotech benchmarking paper exploring this question: bit.ly/3VAMRQs

Tumor Evolution Reconstruction Is Heavily Influenced by Algorithmic and Experimental Choices

Tumor progression is an evolutionary process during which cells acquire distinct genetic alterations. Several cancer evolutionary studies reconstruct this evolutionary process by applying bulk DNA seq...

Reposted by Rija Zaidi

Simone Zaccaria @zaccasimo.bsky.social · 29/11/2024

🚨So proud to present the first study from our @ccg-ucl.bsky.social group together with @charlesswanton.bsky.social @NnennayaKanu and led by @ojlucas.bsky.social with key collaboration @sophie-ward.bsky.social and fundamental support @rijazaidi.bsky.social @abibunkum.bsky.social & others Out now👇 🧵👇

Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER - Nature Genetics

Single-cell Proliferation Rate Inference in Non-homogeneous Tumors through Evolutionary Routes (SPRINTER) allows users to infer proliferation rates of individual clones within a tumor from single-cell...