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Richard Sever

@richardsever.bsky.social
16K followers 426 following 3.1K posts

Chief Science and Strategy Officer, openRxiv. Co-Founder, bioRxiv and medRxiv.

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Richard Sever @richardsever.bsky.social · 6h
I prefaced my question by saying it was a single sentence just with lots of semi-colons...
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Richard Sever @richardsever.bsky.social · 9h
"Jacobsen’s scenario is a poor map of biological risk...stacking worst-case assumptions about pathogen transmissibility, blurring the distinction between dual-use research and weaponization, and overstating what AI changes" thebulletin.org/2026/10/anni...
thebulletin.org
Annie Jacobsen’s road from Siberia to Armageddon is paved with bad assumptions
Following recent reports of a death at a secretive Siberian disease research lab, author Annie Jacobsen has become a sought-after media interview. Some interviewers are now casting Jacobsen's new best...
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Richard Sever @richardsever.bsky.social · 11h
Lanier: "Don't use agents...All AI is is statistical concordance that comes from people. There is no reason to treat it as something with volition. Agent deify AI. Use AI but don't use the agents. That's resistance" #sagebionetworks26
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Richard Sever @richardsever.bsky.social · 11h
Lanier: "Doctors are now using incredible [AI] tools to help patients...Of course those tools were created by people who want to make us all extinct" #sagebionetworks26
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Richard Sever @richardsever.bsky.social · 11h
Jaron Lanier: "AI culture features a preponderance of young men...with a greater ease of abstraction than dealing with humans...It is essentially a new religion" #sagebionetworks26
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Dorothy Bishop @deevybee.bsky.social · 12h
haha. Reminds me of a memorable (apocryphal) meeting of the EPS where the chair responded to a questioner with “if you want to give a talk, you need to get your abstract in on time”
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Richard Sever @richardsever.bsky.social · 12h
"A question is a short sentence that ends in a question mark". Conference attendee guidance from @wilbanks.bsky.social at #saegeassembly26 that all should observe
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Richard Sever @richardsever.bsky.social · 12h
I'd start by pointing out W&C never claimed to discover that DNA was the genetic material...Their paper was about its structure.
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Richard Sever @richardsever.bsky.social · 12h
great to be hubristic and wrong!
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Richard Sever @richardsever.bsky.social · 13h
Welcome to F1000
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Richard Sever @richardsever.bsky.social · 14h
bsky.app/profile/rich...
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Richard Sever @richardsever.bsky.social · 14h
no - unretracted papers widely believed to be wrong but still cited (mainly by their authors)
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Richard Sever @richardsever.bsky.social · 14h
the less strict ones exist: Zenodo, Figshare, Vixra. More strict ones would have higher costs and I think then we are really talking about journals...
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Richard Sever @richardsever.bsky.social · 14h
yeah - publisher-owned preprint servers are a different category. And of course these are primarily intended as previews of content under review they aim to funnel into a journal - as depicted here journals.plos.org/plosbiology/...
journals.plos.org
Biomedical publishing: Past historic, present continuous, future conditional
Academic journals have been publishing the results of biomedical research for more than 350 years. Reviewing their history reveals that the ways in which journals vet submissions have changed over tim...
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Richard Sever @richardsever.bsky.social · 14h
as happens with journal articles...
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Richard Sever @richardsever.bsky.social · 14h
I don't think so. I suspect the non-profit servers will converge on similar approaches for human-authored content (where the $ mean they can), but there may be a different universe of unverified/AI content beyond simply Zenodo/Figshare.
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Richard Sever @richardsever.bsky.social · 15h
Pre-hoc: Volume…and trust. if noise:signal becomes vast the resource uses utility (and costs become unsustainable). Whatever one thinks of the new arXiv policy, that’s basically the reason. Post-hoc: trickier but we want parent institutions to take responsibility for outright fraud
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Richard Sever @richardsever.bsky.social · 15h
Arsenic life is a good example. No one claims bad intent; they just think it’s wrong. Most people nevertheless thought it should be retracted. Science did retract it but notably one ex-Science editor argued they should not have.
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Richard Sever @richardsever.bsky.social · 15h
Yes - otoh we do retract honestly created papers where deep flaws emerge afterwards. Sometimes the authors concede those; sometimes they don’t.
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Richard Sever @richardsever.bsky.social · 15h
Yeah - I also think it doesn’t work when it comes to things like ethical issues. These can be a nightmare, take vast amounts of staff time and need a designated third-party arbiter. Very underappreciated (by academics) part of the process.
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Richard Sever @richardsever.bsky.social · 08/10/2026
But it’s a really important thing to think about in the context of proposals for publishing reform. Publish-Review-Curate and ‘preprint-only’ policies are currently pushed by various funders, but what do retractions look like in these workflows and who arbitrates them?
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Richard Sever @richardsever.bsky.social · 08/10/2026
2) Does intent make a difference? 3) is it different if the venue makes some claim to have verified the content (biorxiv is not a journal, would someone asked the same question of Zenodo?, etc. 4) Does the scale of the problem change things?
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Richard Sever @richardsever.bsky.social · 08/10/2026
There are multiple strands here. 1) the general question of how we as a community handle work judged wrong (do we retract Pauling’s paper on DNA structure - is there a statute of limitations? How is the water memory paper still out there? Was it right to retract As life?)
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Richard Sever @richardsever.bsky.social · 08/10/2026
The question is whether this should be any different from preprints fabricated without AI…
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Richard Sever @richardsever.bsky.social · 08/10/2026
🤣
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Richard Sever @richardsever.bsky.social · 08/10/2026
And finally any version of “Do you know who I am?”. Really no answer to that benefits you in the face of a rejection, and worst-case scenario the retort will be “yeah and you’re lucky we didn’t factor that in to the decision”. 🤣
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Richard Sever @richardsever.bsky.social · 08/10/2026
Other strategies not recommended: citing work by Galileo, Prusiner or Watson & Crick as comparable scenarios.
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Richard Sever @richardsever.bsky.social · 08/10/2026
“This guy’s cursing me up. I better reconsider my decision”, said no editor ever…
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Richard Sever @richardsever.bsky.social · 08/10/2026
See you there!
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Richard Sever @richardsever.bsky.social · 07/10/2026
"OA the warm-up act for AI...Most authors don't read the small print...don't realize what they're giving away". Science & Nature editors on the drawbacks of CC BY licenses. I don't agree with all they say but have always said we need more debate and less dogmatism on this youtu.be/Q04PAohvSYU?...
youtu.be
Who Did the Analysis? Editors on Disclosure and Peer Review in the Age of AI Agents
YouTube video by Broad Institute
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Richard Sever @richardsever.bsky.social · 07/10/2026
Nature E-i-C @magdalenaskipper.bsky.social: "peer reviewers are much harsher critics...Editors are more likely to say let's publish it [as is]" Important in the context of accusations it's "journals" demanding more experiments of authors. youtu.be/Q04PAohvSYU?...
youtu.be
Who Did the Analysis? Editors on Disclosure and Peer Review in the Age of AI Agents
YouTube video by Broad Institute
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Victoria Strauss @victoriastrauss.com · 07/10/2026
Canada is refusing to issue ISBNs to books primarily generated with AI. This illustrates both the urgency of the problem of the growing flood of slop books, and also the toothlessness of addressing it on the honor system without there also being consequences for lying
Use of artificial intelligence
By registering with ISBN Canada, you declare that your book was created by a human author. You may use AI tools only for limited support tasks, such as brainstorming ideas, checking grammar, or formatting your book. You must not use AI to generate the text, create the artwork, or translate the book. ISBN Canada does not issue ISBNs for works whose content is primarily generated by AI. LAC is currently reviewing its policy regarding the use of AI content creation and our guidance is subject to change.
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John Ross @johnrossmd.bsky.social · 07/10/2026
The annual curve of flu cases is starting to rise sharply in the US. This would be a great week to get vaccinated, if you haven't already
Influenza Positive Tests Reported to CDC by Clinical Laboratories,
National Summary, 2025-26 Season, week ending Sep 26, 2026. From: https://www.cdc.gov/fluview/surveillance/2026-week-38.html
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Nathaniel Comfort @nccomfort.bsky.social · 06/10/2026
Reposting for the morning crowd my mini-thread from yesterday on the new Sponsel & Sutton paper on Rosalind Franklin's work. tl;dr: Why didn't Franklin find the double helix? Because she wasn't looking for it! She had her own DNA project that had nothing to do w/ the gene.
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Richard Sever @richardsever.bsky.social · 06/10/2026
And TMV. Is it safe to say she might have got a Nobel for that had she not died before it was awarded?
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Richard Sever @richardsever.bsky.social · 05/10/2026
this should be fixed now - let us know if you are still having problems.
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Richard Sever @richardsever.bsky.social · 05/10/2026
Impact Factors 👇
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Richard Sever @richardsever.bsky.social · 05/10/2026
It’s not even a mean as the numerator and denominator are from different data sets 🤪
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Juan Nunez-Iglesias @jni.codes · 05/10/2026
You may be horrified to learn that at Monash until recently (not sure if still true or not) one of the measures was, I shit you not, “Cumulative Impact Factor”, which is the *sum* of the IFs of the journal of each of your papers.
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Benoit Bruneau @benoitbruneau.bsky.social · 04/10/2026
Happy Pluripotency Day! #Oct4
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Richard Sever @richardsever.bsky.social · 04/10/2026
Interestingly Claude could only identify one and it didn’t have many reviews…
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Richard Sever @richardsever.bsky.social · 04/10/2026
Wanted: email client plug-in that filters AI-generated emails to a separate inbox I pay almost as little attention to as the spam folder...
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Richard Sever @richardsever.bsky.social · 04/10/2026
I use both. Pangram tends to have more false negatives and GPTzero more false positives IME but not always. The browser plug is handy though
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Richard Sever @richardsever.bsky.social · 04/10/2026
Yeah but I feel the impact on math is more radical. Fundamental change in a fundamental type of knowledge generation.
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Richard Sever @richardsever.bsky.social · 03/10/2026
And your regular reminder of the innumeracy of this metric (a pseudo mean calculated from two different datasets and applied to a non-normal distribution) www.biorxiv.org/content/10.1...
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Richard Sever @richardsever.bsky.social · 03/10/2026
Any sane academic evaluation policy would forbid mention of Impact Factor
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Richard Sever @richardsever.bsky.social · 03/10/2026
yes - this to me is a massive question. no user is really faced with the true cost. I've seen estimates for how much a chatbot query actually costs and they are shocking. The response is usually "tech costs will come down", but this is energy costs and if we could have solved them....
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Richard Sever @richardsever.bsky.social · 03/10/2026
bsky.app/profile/need...
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Richard Sever @richardsever.bsky.social · 03/10/2026
you never know. I was very impressed with Elham Azizi youtu.be/PzsUUbiliH0?...
youtu.be
Interview with: Elham Azizi
YouTube video by CSHL Leading Strand
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Richard Sever @richardsever.bsky.social · 03/10/2026
GPTzero has a good chrome plug-in. I am relieved to see it identify all my Gdocs as 100% human
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