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Rémi Tuffet

@remituffet.bsky.social
45 followers 77 following 11 posts

Mathematical modelling and theory in ecology, evolution and epidemiology 2025-: Post-doc at IEES/IPL (Paris, France) 2021-2025: PhD at LBBE/CIRI labs (Lyon, France)

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Rémi Tuffet @remituffet.bsky.social · 31/08/2026
By unifying these two perspectives on the maintenance of diversity, we demonstrate how the eco-evolutionary assembly of plasmids leads to the emergence of three functionally distinct plasmid clusters, associated with simulated abundance distribution that accurately fits the observed one.
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Rémi Tuffet @remituffet.bsky.social · 31/08/2026
On the other hand, even in the absence of trait differences, demographic and environmental stochasticity allow for the sustainable maintenance of the simulated plasmid diversity, which accurately fits the observed diversity, provided that dispersion and innovation are taken into account.
When chance, dispersal among bacterial populations, and innovation sustain plasmid diversity.
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Rémi Tuffet @remituffet.bsky.social · 31/08/2026
We propose an eco-evolutionary mathematical model of competition among plasmids in a bacterial (meta-)population to explore the mechanisms that may explain the maintenance of this diversity. On the one hand, differences in traits associated with environmental fluctuations allow plasmids to coexist.
From exclusion to coexistence: how antibiotic stress shapes plasmid competition. Stress regimes flip the competitive balance
between plasmids, sometimes creating room for coexistence.
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Rémi Tuffet @remituffet.bsky.social · 31/08/2026
Plasmid assemblages, like many macro-organism communities, display striking diversity. This raises a question that has occupied ecologists for decades: How can so many plasmids coexist despite competing with each other?
Similar Diversity Structures in Plasmid and Ecological Communities. Rank-abundance curves and size distribution are represented for (A & D) plasmids of Escherichia coli; (B & E) temperate birds and (C & F) tropical trees.
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