iiinova — where your digital self keeps evolving

the Coup Chronicle @redargutor.bsky.social · 08/06/2026

Quickly? 15-20 years from discovery to approval is quite normal. And no nothing to do with it.

Reposted by the Coup Chronicle

Alt National Park Service @altnps.bsky.social · 08/06/2026

DC Arch public comments are now open. As much as many of us would like to simply submit “FDT,” comments are far more likely to be considered if they raise specific concerns about the project. Federal agencies are only required to consider substantive comments,

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the Coup Chronicle @redargutor.bsky.social · 28/05/2026

Only in Denmark, for less than $5 you can be the proud owner of the one and only Trump toilet brush 😂

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the Coup Chronicle @redargutor.bsky.social · 03/04/2026

Ahh, good. You never know nowadays 🫣

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the Coup Chronicle @redargutor.bsky.social · 30/03/2026

It took him only 5 weeks to admit he wants their oil 🙄

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the Coup Chronicle @redargutor.bsky.social · 04/03/2026

Joint operation with Europol and several European countries initiated by the Biden administration

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the Coup Chronicle @redargutor.bsky.social · 04/03/2026

Haha, I approve 😉. not likely though when he can wear a buttoned shirt

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the Coup Chronicle @redargutor.bsky.social · 04/03/2026

yes, I know it’s an expression 🙄. The US being part of a long term international operation in Ecuador, together with Europol and several European countries, to counteract a large drug cartel is good news.

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the Coup Chronicle @redargutor.bsky.social · 04/03/2026

reading up on a subject before making statements would stop your head from spinning

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the Coup Chronicle @redargutor.bsky.social · 04/03/2026

Please read the article before commenting 🙄. Has nothing to do with war

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the Coup Chronicle @redargutor.bsky.social · 04/03/2026

There is no new war. Just a planned operation, also including several European countries.

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the Coup Chronicle @redargutor.bsky.social · 04/03/2026

Please stop commenting on stuff if you haven’t bothered to read up on what is actually going on. Nothing to do with a new war, but planned operation also including several European countries 🙄

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the Coup Chronicle @redargutor.bsky.social · 01/03/2026

Sure, we could try diplomacy—right after we finish stirring the hornet’s nest and asking them to calm down about it

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the Coup Chronicle @redargutor.bsky.social · 01/03/2026

This is actually quite normal in the history of the US: Grenada, Panama, Kosovo, Lybia, etc etc, all without congress being involved.

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the Coup Chronicle @redargutor.bsky.social · 01/03/2026

Iran has vowed to retaliate. The world may be on the edge of something far more serious than we’ve seen in decades… if not longer.

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the Coup Chronicle @redargutor.bsky.social · 01/03/2026

When you call a nation a strategic partner, while it treats dissent as treason, you’re not just compromising your values — you’re compromising your judgment. At some point, you have to ask yourself what exactly you’re partnering with. After all, they were the ones pushing for the strike on Iran.

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the Coup Chronicle @redargutor.bsky.social · 28/02/2026

When Russia attacked Ukraine, sanctions were imposed quickly. Can we expect a similar response this time? Rhetorical question of course, we all know the answer.

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the Coup Chronicle @redargutor.bsky.social · 28/02/2026

To be fair, the last time congress declared a war was WW2...

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the Coup Chronicle @redargutor.bsky.social · 28/02/2026

So let me get this straight: a regime that represses its own people gets attacked by a country with a genocide on its résumé, teamed up with another country that happily brutalizes both foreigners and citizens, all because they’re worried the first regime might want the same nuclear toys they have

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the Coup Chronicle @redargutor.bsky.social · 13/02/2026

Imo, he doesn’t need to do any of these things. There is no way he won all swing states last time, hence they know of a way to manipulate the results without having to resort to the scenarios you describe.

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the Coup Chronicle @redargutor.bsky.social · 12/02/2026

He doesn’t have Alzheimer’s, but frontotemporal dementia fits perfectly

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the Coup Chronicle @redargutor.bsky.social · 11/02/2026

true! and when you mention that peaceful protests wont bring down a new authoritarian regime, people call you a bot

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the Coup Chronicle @redargutor.bsky.social · 11/02/2026

IMO, the system is the problem, not the companies as such. And many Americans prefer lower taxes even if it means higher healthcare costs, while many European countries fund cheaper care through 30–40% income taxes. You can’t have both low taxes and low healthcare prices, unfortunately

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

FDA nowadays can’t be trusted anymore, and the FDA had no regulatory authority over tobacco until 2009, as it wasn’t a drug.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

As I mentioned before, that’s a failure of the U.S. pricing system, not something inherent to the drug itself. It doesn’t change the fact that Novo reinvests a large share of its profits into R&D and funds basic research globally.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

US lobbying power affects pricing laws, patent protections, Medicare negotiation rules, and regulatory burdens. It does not mean companies can simply “buy” drug approvals or suppress safety data within the FDA process. The influence is structural and political, not an override of scientific review.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

That’s not how FDA approval works. this whole thread started with Wegovy, a drug developed in Denmark, where pharmaceutical companies don’t lobby their government the way U.S. companies do. The idea that lobbying somehow guarantees profit while suppressing inconvenient studies doesn’t match reality

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

Oh, you again. Thanks for stepping in to prove the Dunning–Kruger point so neatly — absolutely convinced you know better than someone who’s worked in the field for decades, yet still avoiding any factual discussion.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

Yep, he is an ass. You will find them in any branch. Doesn’t mean everyone is equally corrupt.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

I give up. There’s no point debating someone who doesn’t understand the complexity of the topic but is absolutely convinced they’re right. have a nice day

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

I’m done. It’s impossible to have a real discussion with someone who’s so sure of their opinion yet doesn’t grasp the complexity of the topic.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

It seems the conversation shifted from facts to personal remarks. I have been working in drug discovery for a long time, while based on your remarks, you clearly have not, so there is nothing left to debate.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

You talked about having a 2 sec search, not me. Btw Novo Nordisk does not get publicly funded grants for doing commercial R&D. They may be co-applicants on academic projects about basic research, but that is something different.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

Love the confidence — must be nice not having facts get in the way

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

You’re arguing from assumptions, not how the industry actually works.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

A for‑profit company isn’t going to sell at a loss, but it’s inaccurate to claim “the rest is cheap once the drug is developed.” For many modern medicines, manufacturing, scaling, compliance, and maintaining dedicated production lines remain major ongoing costs, not negligible ones.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

Manufacturing costs aren’t one‑size‑fits‑all. Some are cheap, but many aren’t — eg biologics, sterile injectables, and anything requiring living systems or ultra‑tight quality controls. Infrastructure is also drug‑specific: different products need different facilities, equipment, and validation

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

this doesn‘t prove the entire pharmaceutical industry only wants profit, but shows how a specific U.S. market structure failed. It doesn’t reflect how R&D works, where companies spend billions on candidates that never reach approval and rely on a few successes to fund the many failures.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

2-And even for the few that make it through approval, the costs of large‑scale manufacturing, validation, and distribution aren’t included in that comparison at all, so the figure ends up being misleading.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

1-Hard to argue from that figure alone as it treats all “basic research” as if it were equally relevant, whereas the majority never produces anything that can become a drug candidate. Only a tiny fraction ever reaches preclinical development, and most of those fail before or during clinical trials.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

What I quickly could find is that Eli Lilly‘s 2025 R&D budget is larger than either its 2024 net income or operating cash flow, meaning that the company is willing to spend more than last year’s profit or cash flow on R&D, which is the opposite of the “they just enrich themselves” narrative.

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the Coup Chronicle @redargutor.bsky.social · 10/02/2026

No. Translating publicly funded basic findings into actual, safe, scalable drugs is an enormous, high‑risk, and very expensive effort. Most candidates fail long before they reach patients, and those late‑stage trials, manufacturing build‑outs, and regulatory hurdles are all financed by companies

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