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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 11/09/2026

🚨🦟 Reviews are in! Reviewers consider this a promising modeling study, but raise major concerns about model validity, biological assumptions, and interpretation of transmission outcomes. rrid.mitpress.mit.edu/pub/80qx2wdg...

rrid.mitpress.mit.edu

Reviews of: "Modeling Mosquito Control Strategies and Their Effect on Pathogen Transmission"

Reviewers: J McMillan (Texas Tech University) | 📒📒📒 ◻️◻️ • A Adekunle & S Ogunlade (James Cook University) | 📒📒📒 ◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 16/08/2026

🚨🌶️ Reviews are in for a preprint showing trans-cinnamaldehyde boosts fosfomycin against drug-tolerant uropathogenic E. coli, highlighting a promising antibiotic adjuvant strategy calling for mechanistic evidence and validation in UTI models. rrid.mitpress.mit.edu/pub/s9xstdwb...

rrid.mitpress.mit.edu

Reviews of: "Spicing Up Urinary Tract Infections: Synergistic Action of Fosfomycin with Trans-cinnamaldehyde - insight to the Mode of Action"

Reviewers: H Link (University of Tübingen) | 📗📗📗📗◻️ • Anonymous | 📒📒📒 ◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 30/07/2026

🚨🦠 Reviews are in for a preprint evaluating enterobacterial phage-host resistance dynamics in human urine and demonstrating the value of mathematical modeling for phage therapy design while highlighting important methodological and interpretive limitations. rrid.mitpress.mit.edu/pub/uid6n22u...

rrid.mitpress.mit.edu

Reviews of: "Bacteriophage Heteroresistance as a Cause of Treatment Failure in Urinary Tract Infections"

Reviewers: G Krishnamoorthy (Charité – Universitätsmedizin Berlin) | 📒📒📒 ◻️◻️ • S Nang (Monash University) | 📒📒📒 ◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 22/07/2026

🚨🫁 Reviews are in! Reviewers highlight a well-conducted pragmatic trial showing that AI-guided TB hotspot targeting faced major implementation challenges, with debate over whether higher yields in adherent sites reflect a true effect of the software. rrid.mitpress.mit.edu/pub/w215fovf...

rrid.mitpress.mit.edu

Reviews of: "Geographical targeting of active case finding for tuberculosis in Pakistan using artificial intelligence software (SPOT-TB): a pragmatic stepped wedge cluster randomized control trial"

Reviewers: M Gidado (KNCV Tuberculosis Foundation) | 📗📗📗📗◻️ • C Yuen (Harvard Medical School) | 📒📒📒 ◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 06/07/2026

🚨💉 Read our most recent reviews! Reviewers evaluate this preprint as a valuable contribution suggesting cross-protection among orthoebolavirus vaccines, but caution that findings require confirmation in more representative animal models and vaccine platforms. rrid.mitpress.mit.edu/pub/nauvg6o6...

rrid.mitpress.mit.edu

Reviews of: “Cross-protection against Bundibugyo by Ebola and Sudan vaccines”

Reviewers: A Lehrer & A To (University of Hawai’i at Manoa) | 📒📒📒 ◻️ • D Xu (University of Wisconsin-Madison) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 02/07/2026

🚨🧫 Reviews are in! Reviewers find LUCIA (a cell-free luminescence assay) a promising platform for validating AlphaFold-predicted protein interactions, while cautioning that its benchmarking and proposed confidence thresholds require broader validation. rrid.mitpress.mit.edu/pub/m1jhq8bt...

rrid.mitpress.mit.edu

Reviews of: "Systematic Validation of AlphaFold-Predicted Interactomes with LUCIA"

Reviewers: J Gsponer (University of British Columbia) | 📒📒📒 ◻️◻️ • M Varjosalo (University of Helsinki) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 16/06/2026

🚨🌎 Reviews are in for a preprint mapping animal contact associated Salmonella enterica outbreaks across the United States, identifying persistent regional hotspots and demonstrating the value of spatial epidemiology for public health surveillance. rrid.mitpress.mit.edu/pub/dl1w09m5...

rrid.mitpress.mit.edu

Reviews of: "Mapping High Rate Clusters of Animal Contact Related Human Salmonella enterica Single State Outbreaks in the United States, 2009 to 2022. A Spatial Epidemiological Approach to Inform Publ...

Reviewers: A Gourishankar (Children's National Research Institute) | 📗📗📗📗◻️ • Anonymous | 📒📒📒 ◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 27/05/2026

🧬🚨Repurposed antipsychotic Spiperone suppresses HBV replication and targets cccDNA, the persistent viral reservoir blocking HBV cure, through ER stress-induced innate immune activation and epigenetic silencing. rrid.mitpress.mit.edu/pub/hur7h231...

rrid.mitpress.mit.edu

Reviews of "Spiperone Targets HBV cccDNA via ER Stress-Induced Innate Immune Activation and Epigenetic Silencing"

Reviewers: K Kim (Ajou University) | 📗📗📗📗◻️ • Y Xia & L Zhang (Wuhan University) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 27/05/2026

📣📣CALLING ALL STUDENTS Are you interested in infectious disease research, scientific communication, and combating misinformation? If YES, join us 5/27 to learn more about RR\ID - a student-led global initiative addressing just that. RSVP here: forms.gle/8PibLQ3DgoTV...

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 15/05/2026

🔊🚨S2DI may help bridge stewardship metrics and daily clinical practice by standardizing measurement of antibiotic prescribing appropriateness in hospitalized patients with bacteremia and enabling national monitoring of de-escalation practices. rrid.mitpress.mit.edu/pub/mq9lwout...

rrid.mitpress.mit.edu

Reviews of

Reviewers: R Somayaji & J Burke-Gaffney (University of Calgary) | 📕 ◻️◻️◻️◻️ • F Fiol (University of Sorocaba) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 13/05/2026

🚨🫁Reviews are in for a preprint investigating the cross-border transmission of Rwanda’s dominant multidrug-resistant tuberculosis clone using targeted molecular diagnostics. rrid.mitpress.mit.edu/pub/anrtx70p...

rrid.mitpress.mit.edu

Reviews of

Reviewers: V Crudu (Nicolae Testemitanu State University) | 📗📗📗📗◻️ • R Salvato (Federal University of Health Sciences of Porto Alegre) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 05/05/2026

🚨‼️Reviews are in for a preprint that identifies HNRNPA2B1 as a host RNA-binding protein that helps repress Epstein-Barr virus lytic reactivation. rrid.mitpress.mit.edu/pub/ozi5ysvp...

rrid.mitpress.mit.edu

Reviews of

Reviewers: L Muñoz (Wistar Institute) | 📘📘📘📘📘 • B Glaunsinger (UC Berkeley) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 04/05/2026

🔊New research highlights quinolone-based compounds that target parasite mitochondria and show activity against chronic Toxoplasma infections, pointing toward potential next-generation treatments. rrid.mitpress.mit.edu/pub/shhtk7dh...

rrid.mitpress.mit.edu

Reviews of

Reviewers: S Besteiro (Université de Montpellier) | 📘📘📘📘📘 • P Sijwali (Centre for Cellular and Molecular Biology) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 23/04/2026

‼️🚨Wastewater WGS caught measles transmission chains that routine clinical surveillance missed in South Africa's 2024–25 outbreak — and did it at population scale. Evidence rated Reliable. #MeaslesSurveillance #WastewaterEpidemiology rrid.mitpress.mit.edu/pub/80r20v55...

rrid.mitpress.mit.edu

Reviews of

Reviewers: M Kitajima, K Matsumoto, R Gomi (The University of Tokyo) | 📗📗📗📗◻️ • S Fu (Northwest University) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 21/04/2026

🚨🚨Reviews in: This study provides strong proof of concept that adenine base editing can effectively disable HBV and HDV reservoirs, though reviewers emphasize the need for more rigorous off-target safety analysis. rrid.mitpress.mit.edu/pub/zgobq3jv...

rrid.mitpress.mit.edu

Reviews of

Reviewers: L Tang (Baruch S. Blumberg Institute) | 📘📘📘📘📘 • G Mehar (UC Berkeley) | 📗📗📗📗◻️ • H Yang (National Taiwan University) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 21/04/2026

‼️📣Even pyrethroid-resistant mosquitoes can't escape this innovation. A new spatial emanator reduces malaria vector bites by 43% in West Africa—offering hope where resistance has thwarted nets. #MalariaControl #VectorScience rrid.mitpress.mit.edu/pub/wfcx3u6p...

rrid.mitpress.mit.edu

Reviews of

Reviewers: E Walker (Michigan State University) | 📘📘📘📘📘 • I Hennessee (The Carter Center) | 📒📒📒◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 21/04/2026

‼️🚨Reviews are out for a preprint evaluating whether machine learning models using pharmacy refill adherence can predict HIV viral suppression in resource-limited settings. rrid.mitpress.mit.edu/pub/500n02oo...

rrid.mitpress.mit.edu

Reviews of

Reviewers: C Lu & C Najjuuko (Washington University in St. Louis) | 📒📒📒 ◻️◻️ • D Salami (University of Maryland) | 📕 ◻️◻️◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 14/04/2026

🔊🔊NEW: This preprint identifies GFI1 as a potential regulator of HIV silencing, using a dual-reporter system with single-cell RNA-seq and functional assays addressing the underexplored aspect of HIV latency in hematopoietic stem and progenitor cells (HSPCs). rrid.mitpress.mit.edu/pub/kgjb5d79...

rrid.mitpress.mit.edu

Reviews of

Reviewers: M Tyagi (Thomas Jefferson University) | 📗📗📗📗◻️ • D Kulpa (Emory University) | 📒📒📒◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 07/04/2026

📃🚨Reviews are in for a preprint that characterizes a new group of anti-CRISPR proteins that transcriptionally silence CRISPR-Cas systems. rrid.mitpress.mit.edu/pub/du2hy43i...

rrid.mitpress.mit.edu

Reviews of

Reviewers: J Wade (University at Albany) | 📗📗📗📗◻️ • M White (University of St Andrews) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 31/03/2026

📣📣This preprint shows that gut metabolites, especially indoles, can suppress enterobacterial growth and invasiveness. It highlights anti-virulence strategies as promising alternatives to traditional antibiotics. rrid.mitpress.mit.edu/pub/cbxyl0q8...

rrid.mitpress.mit.edu

Reviews of

Reviewers: P Lele, S Mukhopadhyay and P Subrahmaniyan (Texas A&M University) | 📒📒📒 ◻️◻️ • R Sinha (Michigan State University) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 31/03/2026

🚨‼️Point-of-care CD4, TB-LAM, and CrAg testing by trained lay providers show high accuracy and promise as a low-cost alternative to expand decentralized advanced HIV disease and opportunistic infection screening. rrid.mitpress.mit.edu/pub/0kqrlkzr...

rrid.mitpress.mit.edu

Reviews of

Reviewers: E Spooner (South African Medical Research Council) | 📗📗📗📗◻️ • J Jarvis (London School of Hygiene & Tropical Medicine) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 17/03/2026

🔊🚨Check out our reviews on a genome-wide screen on Mycobacterium smegmatis, a model organism for tuberculosis, leprosy, and other diseases, bringing us closer to understanding how this organism's phenotype changes under exposure to a variety of chemicals. rrid.mitpress.mit.edu/pub/oh1fd26f...

rrid.mitpress.mit.edu

Reviews of

Reviewers: K Mikusova & S Huszár (Comenius University Bratislava) | 📘📘📘📘📘 • S Hasnain (Sharda University) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 26/02/2026

🚨‼️Check out reviews for a manuscript describing SeaB as a surface-exposed autotransporter involved in aggregation, biofilm formation, extracellular matrix binding, virulence, and as a potential vaccine candidate! rrid.mitpress.mit.edu/pub/uqu15es2...

rrid.mitpress.mit.edu

Reviews of

Reviewers: C Beloin (Institut Pasteur) | 📘📘📘📘📘 • Anonymous | 📗📗📗📗◻️ • J Leo (Nottingham Trent University) | 📗📗📗📗◻️

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Reposted by Rapid Reviews\Infectious Diseases Journal

MIT Press @mitpress.bsky.social · 17/02/2026

@rapidreviews-id.bsky.social is an #OA overlay journal that accelerates peer review of important infectious disease-related research preprints. A new review looks at how West Nile Virus can lead patients to develop autoimmune responses, which can lead to more severe infections:

rrid.mitpress.mit.edu

Reviews of "Autoantibodies Neutralizing Type I IFNs in 40% of Patients with WNV Encephalitis in Seven New Cohorts"

Reviewers: J Beckham & J Berger (University of Texas Southwestern) | 📘📘📘📘📘 • B Strunz (Karolinska Institutet) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 11/02/2026

🚨‼️🚨Reviews in: This preprint shows that the nasopharyngeal microbiome composition may be associated with rapid mortality in children hospitalized with pneumonia in low- and middle-income countries. rrid.mitpress.mit.edu/pub/uopl7jq4...

rrid.mitpress.mit.edu

Reviews of

Reviewers: Anonymous | 📒📒📒 ◻️◻️• Anonymous | 📒📒📒 ◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 10/02/2026

‼️🔊🔊Reviews are in for "Early-life gut microbiome is associated with immune response to the oral rotavirus vaccine in healthy infants in the US", rated "reliable"/"potentially informative" by reviewers. rrid.mitpress.mit.edu/pub/pax7jwgd...

rrid.mitpress.mit.edu

Reviews of

Reviewers: A Vlasova (The Ohio State University) | 📒📒📒 ◻️◻️ • S Ali (Aga Khan University) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 10/02/2026

🦟‼️🚨Reviews are in for a preprint examining antibody responses to the DBL5 domain of VAR2CSA in pregnancy-associated malaria. rrid.mitpress.mit.edu/pub/omupkz1s...

rrid.mitpress.mit.edu

Reviews of

Reviewers: F Osier (Imperial College London) | 📒📒📒 ◻️◻️ • G Wright & J Whitehead (University of York) | 📙📙 ◻️◻️◻️

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Reposted by Rapid Reviews\Infectious Diseases Journal

ASAPbio @asapbio.bsky.social · 27/01/2026

🚀 We are excited to see many initiatives that are working hard to publicly assess preprints. 🚀Today, we want to highlight one of them-- @rapidreviews-id.bsky.social ! RR\ID is "an open-access overlay journal that accelerates peer review of important infectious disease-related research preprints."

rrid.mitpress.mit.edu

Rapid Reviews Infectious Diseases

RR\ID is an open-access overlay journal that accelerates peer review of important infectious disease-related research preprints.

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 26/01/2026

‼️🚨📣Reviews are in for a preprint which shows that mitochondrial rewiring in immature neutrophils promotes degranulation and endothelial dysfunction in malaria and sepsis, revealing shared inflammatory mechanisms across infections. rrid.mitpress.mit.edu/pub/six43z0u...

rrid.mitpress.mit.edu

Reviews of

Reviewers: B Mishra (Albany Medical College) | 📘📘📘📘📘 • B Yipp (University of Calgary) | 📒📒📒◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 22/01/2026

‼️🚨🔊Check out our reviews on how West Nile Virus can lead patients to develop autoimmune responses which can lead to more severe infections. rrid.mitpress.mit.edu/pub/vokdv8pv...

rrid.mitpress.mit.edu

Reviews of

Reviewers: J Beckham & J Berger (University of Texas Southwestern) | 📘📘📘📘📘 • B Strunz (Karolinska Institutet) | 📘📘📘📘📘

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 15/01/2026

🔊‼️A recent study shows evidence that Plasmodium falciparum–activated immune cells can directly adhere to and damage the blood–brain barrier via inflammatory mechanisms, advancing understanding of immune-driven pathology in cerebral malaria. rrid.mitpress.mit.edu/pub/ujjfxtog...

rrid.mitpress.mit.edu

Reviews of

Reviewers: C Madigan (UC San Diego) | 📗📗📗📗◻️ • Y Zheng (University of Washington) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 14/01/2026

‼️🔊Reviews are in for "Climate warming and urbanization may expand dengue transmission risk in California," a preprint that integrates vector presence, temperature suitability, and travel-related viral introductions to project dengue risk. rrid.mitpress.mit.edu/pub/jndwuiu8...

rrid.mitpress.mit.edu

Reviews of

Reviewers: P Moraga (King Abdullah University) | 📗📗📗📗◻️ • F Sanchez (Universidad de Costa Rica) | 📘📘📘📘📘 • L Stolerman (Oklahoma State University) | 📗📗📗📗◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 13/01/2026

‼️‼️In recent study from Brazil, authors conclude that while combining blood transcriptomic signatures meaningfully improves tuberculosis risk prediction important limitations in specificity, validation, and clinical practicality remain before widespread use. rrid.mitpress.mit.edu/pub/2ycko02m...

rrid.mitpress.mit.edu

Reviews of

Reviewers: D M Cirillo (IRCCS San Raffaele Scientific Institute) | 📗📗📗📗◻️ • A Fiore-Gartland (Fred Hutchinson Cancer Center) | 📒📒📒◻️◻️

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Rapid Reviews\Infectious Diseases Journal @rapidreviews-id.bsky.social · 13/01/2026

🚨🫀Reviews are in for a preprint showing how a minimally adapted H1N1 influenza virus can directly drive cardiac dysfunction in immunocompetent mice and that early pharmacologic activation of AMPK improves electrical abnormalities, fibrosis, and survival. rrid.mitpress.mit.edu/pub/qqybqsuq...

rrid.mitpress.mit.edu

Reviews of

Reviewers: A Rangrez & A Deshpande (Heidelberg University) | 📒📒📒 ◻️◻️ • R Gopal (University of Pittsburgh) |📘📘📘📘📘

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