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Raphaël Clément

@raphclement.bsky.social

223 followers 237 following 17 posts

Biophysics, developmental biology, morphogenesis @ IBDM & Centuri (CNRS / Aix-Marseille Université) raphaelclement.fr

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Raphaël Clément @raphclement.bsky.social · 27/08/2026

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Raphaël Clément @raphclement.bsky.social · 27/08/2026

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Raphaël Clément @raphclement.bsky.social · 27/08/2026

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Raphaël Clément @raphclement.bsky.social · 22/05/2026

Altogether, this work reveals surprising and dynamic locomotion behaviours adapted to environmental cues, and emerging from simple cellular responses in Trichoplax, an animal with no muscles or nervous system.

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Raphaël Clément @raphclement.bsky.social · 22/05/2026

These rapid changes of direction rely on the reorientation of BBs across the whole animal on the timescale of seconds (here cut + 30s). Using pharmacological treatments, we find that the propagation of reorientation relies on voltage-gated Calcium channels.

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Raphaël Clément @raphclement.bsky.social · 22/05/2026

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Raphaël Clément @raphclement.bsky.social · 22/05/2026

We find that Trichoplax also displays rapid negative mechanotaxis in response to local stimuli, like touch or injury

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Raphaël Clément @raphclement.bsky.social · 22/05/2026

By quantifying ciliary basal bodies (BB) orientation at the animal scale with sub-cellular resultion, we find that they dynamically align with the direction of movement. Trichoplax body shape changes result from large-scale gradients of BB orientation.

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Raphaël Clément @raphclement.bsky.social · 22/05/2026

Our work on Trichoplax locomotion and mechanosensing capabilities is out now in @currentbiology.bsky.social. Congrats Marvin Leria & all co-authors! authors.elsevier.com/c/1n8Ig3QW8S...

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Raphaël Clément @raphclement.bsky.social · 29/04/2026

The division Physics and Life of the French Physical Society (SFP) organizes its fourth annual meeting in Lyon, July 9th & 10th! Join us and register here: phys-life-2026.sciencesconf.org Abstract submission deadline: May 30th

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Raphaël Clément @raphclement.bsky.social · 28/01/2026

Super happy to share the exciting work of Emma Legait, showing how neighbourhood composition determines cancer stem cell fate in hierarchical tumours. A great and long-standing collaboration with @cedricmaurange.bsky.social www.biorxiv.org/content/10.6...

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Raphaël Clément @raphclement.bsky.social · 27/08/2025

Mechanosensation and fast reorientation of ciliary structures: Marvin's work on the surprising locomotion capabilities of Trichoplax, an animal without neurons! www.biorxiv.org/content/10.1...

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