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Clara Rehmann

@ramencult.bsky.social

533 followers 73 following 14 posts

twitter user @ramencult raising a bearded dragon, writing in Python, getting a PhD she/her 🏳️‍🌈 clararehmann.github.io

Posts Replies Media

Reposted by Clara Rehmann

pastramimachine @pastramimachine.bsky.social · 08/07/2026

Cyberbullying the bald is not a good look, Matthew.

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Reposted by Clara Rehmann

Matthew Hahn @3rdreviewer.bsky.social · 02/07/2026

My abiding memory of a wonderful #SMBE2026:

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Clara Rehmann @ramencult.bsky.social · 26/04/2026

Ok I’m a doctor #PhDone

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Clara Rehmann @ramencult.bsky.social · 19/04/2026

When the seminar speaker starts talking about autism risk

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Clara Rehmann @ramencult.bsky.social · 05/04/2026

I’m getting old <3 ty ty

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Clara Rehmann @ramencult.bsky.social · 05/04/2026

Posting on Bluesky feels like talking during the parent-teacher conference

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Clara Rehmann @ramencult.bsky.social · 05/04/2026

Defense poster alternates

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Clara Rehmann @ramencult.bsky.social · 05/04/2026

Becoming a doctor this month! DM if you wanna Zoom in

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Reposted by Clara Rehmann

Angel G. Rivera-Colón @arcolon14.bsky.social · 05/03/2026

Check our new preprint from the KR-colab with @ramencult.bsky.social and Andy Kern: MKado: a toolkit for McDonald-Kreitman tests of natural selection doi.org/10.64898/202...

doi.org

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Clara Rehmann @ramencult.bsky.social · 10/02/2025

You can browse our Anopheles analysis (including an interactive frequency-area plot and searchable data table) here: kr-colab.github.io/spatial_swee...

kr-colab.github.io

Anopheles gambiae spatial genome analysis

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Clara Rehmann @ramencult.bsky.social · 10/02/2025

By considering spatial population structure, we ID variants that have not yet been noted by conventional selection scans, generating new hypotheses for avenues of adaptation in An. gambiae and demonstrating our method's potential to identify otherwise-overlooked sweeping alleles.

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Clara Rehmann @ramencult.bsky.social · 10/02/2025

We find enrichments for sensory processing and drug metabolism functions, uncover numerous variants at known insecticide-resistance loci (including Rdl, Ace1, and Cyp6p) and highlight strong spatial-frequency outliers that may have functional consequences!

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Clara Rehmann @ramencult.bsky.social · 10/02/2025

With our sims, we demonstrate that this signal can be used to identify variants under positive selection as outliers in the genome-wide joint distribution. We then leverage this signal to identify potentially-sweeping variants in Anopheles gambiae from West Africa.

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Clara Rehmann @ramencult.bsky.social · 10/02/2025

This is because selection causes these alleles to increase in frequency faster than they can spread through space - conversely, a neutral allele can diffuse across space while remaining at low or intermediate frequencies.

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Clara Rehmann @ramencult.bsky.social · 10/02/2025

While simulating sweeps in two-dimensional space, we observed that selection has a huge impact on the relationship between an allele’s frequency and its range across a landscape: beneficial alleles take up less area relative to their frequency within the population!

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Clara Rehmann @ramencult.bsky.social · 10/02/2025

New preprint! We find a novel signal of positive selection in georeferenced genotype data, then use this signal to identify in-progress selective sweeps in the malaria vector Anopheles gambiae: www.biorxiv.org/content/10.1...

biorxiv.org

Sweeps in space: leveraging geographic data to identify beneficial alleles in Anopheles gambiae

As organisms adapt to environmental changes, natural selection modifies the frequency of non-neutral alleles. For beneficial mutations, the outcome of this process may be a selective sweep, in which a...

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Clara Rehmann @ramencult.bsky.social · 24/01/2025

okay fine

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