Happy to share our latest article on SirT6 😊
In this paper, we demonstrate that SirT6 can efficiently ADP-ribosylate proteins on both histidine and tyrosine residues.
Check it out here:
royalsocietypublishing.org/rsob/article...
royalsocietypublishing.org
Histidine and tyrosine residues are targets for SIRT6 ADP-ribosylation activity
Abstract. SIRT6, a highly conserved member of the sirtuin family, plays a critical role in diverse cellular processes, including gene regulation, DNA damag