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Jens Lundgren

@profjlundgren.bsky.social
643 followers 81 following 57 posts

Infectious diseases, precision medicine, immune impairment,epi&pandemic handling. M: d244139@dadlnet.dk; P:+4540879303; www.chip.dk; vildvirus.dk

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Jens Lundgren @profjlundgren.bsky.social · 28/12/2025
Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis | New England Journal of Medicine www.nejm.org/doi/full/10.... More the marier is not always true.
nejm.org
Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis | NEJM
Tuberculous meningitis is often lethal, and many survivors have disabilities despite antimicrobial treatment and adjunctive glucocorticoid therapy. Standard-dose rifampin has limited central nervou...
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Jens Lundgren @profjlundgren.bsky.social · 10/10/2025
I godt selskab her til eftermiddag- rundt om SMS’er corona jødehad nobelprisvindere og meget andet. @henrikq.bsky.social podcasts.apple.com/dk/podcast/i...
podcasts.apple.com
Men Pia Kjærsgaard, Jens Lundgren og Niels Thulesen Dahl
Podcastepisode · I selskab med Q · 10.10.2025 · 1 t. 4 min.
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Jens Lundgren @profjlundgren.bsky.social · 07/06/2025
Addressing Antifungal Drug Resistance — A “One Health–One World” perspective www.nejm.org/doi/full/10....
nejm.org
Addressing Antifungal Drug Resistance — A “One Health–One World” Challenge | NEJM
Use of some antifungal pesticides may select for resistant fungi in the environment, which can then endanger human health. Coordinated regulatory processes in this area are important.
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Jens Lundgren @profjlundgren.bsky.social · 07/06/2025
Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis | New England Journal of Medicine www.nejm.org/doi/full/10....
nejm.org
Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis | NEJM
Semaglutide, a glucagon-like peptide-1 receptor agonist, is a candidate for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). In this ongoing phase 3, multicenter, randomize...
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Jens Lundgren @profjlundgren.bsky.social · 07/06/2025
Additional evidence supporting benefits from exercise after adjunct Chemotherapy for Colon Cancer. www.nejm.org/doi/full/10....
nejm.org
Structured Exercise after Adjuvant Chemotherapy for Colon Cancer | NEJM
Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence is lacking. In this phase 3, randomized trial conducted at 55 centers, ...
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Jens Lundgren @profjlundgren.bsky.social · 27/05/2025
www.linkedin.com/posts/profje...
linkedin.com
Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza -… | Jens Lundgren
Anti-influenza antivirals to reduce risk of transmission of influenza #InfluenzaTransmission #Prevention https://lnkd.in/d3Ry7kPS
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Jens Lundgren @profjlundgren.bsky.social · 15/05/2025
Skrevet kronik med @SørenBrostrøm om de udfordringer som sundhedsforskning pt er udsat for globalt. www.berlingske.dk/kronikker/na... #forskning #onehealth
berlingske.dk
Når Trumps regering bedriver holdningsmæssig heksejagt på USAs sundhedsinstitutioner, påvirker det også resten af verden
Læs mere her.
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Jens Lundgren @profjlundgren.bsky.social · 15/05/2025
Skrevet kronik med @SørenBrostrøm om de udfordringer som sundhedsforskning pt er udsat for globalt. www.berlingske.dk/kronikker/na... #forskning #onehealth
berlingske.dk
Når Trumps regering bedriver holdningsmæssig heksejagt på USAs sundhedsinstitutioner, påvirker det også resten af verden
Læs mere her.
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Jens Lundgren @profjlundgren.bsky.social · 02/05/2025
Super godt og sjovt selskab - om alt og intet den sidste uge. Hør med. podcasts.apple.com/dk/podcast/i...
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Jens Lundgren @profjlundgren.bsky.social · 28/04/2025
Undetectable=Untransmittable - a slogan in HIV medicine informed by solid evidence that #CHIP has contributed with. See link via linkedin.com below for details. www.linkedin.com/posts/profje...
linkedin.com
AIDS 2018 Co-chairs' choice | Jens Lundgren
Is persons with well-treated HIV still infectious: No, they are not !!! The Danish AIDS foundation celebrated its 40 years anniversary last Friday. We were recognised with an award for contributing ...
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Jens Lundgren @profjlundgren.bsky.social · 18/04/2025
MPox, regulators, funding and NIAID. Longer piece - please review, comment and share. Thanks. www.linkedin.com/posts/profje...
linkedin.com
Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo… | Jens Lundgren
Treatment of Mpox: the drug regulators and clinicians though worked and used for routine care, failed to show efficacy in this state-of-the-art designed placebo-controlled trial. #MPoxTherapy #Clini...
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Jens Lundgren @profjlundgren.bsky.social · 12/04/2025
Important data generated by #ECDC @teynoori.bsky.social - thanks
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Lars Løkke Rasmussen @lars-loekke.bsky.social · 28/03/2025
Dear American friends. We agree that status quo in the Artcic is not an option. So let’s talk about how we can fix it - together. Lars Løkke Rasmussen Danish Foreign Minister
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Jens Lundgren @profjlundgren.bsky.social · 27/03/2025
Var i deadline. #fugleinfluenza #pandemi #unødigFrygt www.dr.dk/nyheder/indl...
dr.dk
Der kommer en dag en ny pandemi. Men den kommer ikke til at starte i danske svinestalde, vurderer professor
Forfatter Mathilde Walter Clark advarer om, at svin kan udløse den næste pandemi. Men professor Jens Lundgren vurderer, at risikoen er ekstremt lille.
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Jens Lundgren @profjlundgren.bsky.social · 07/03/2025
Haft en forrygende samtale i eftermiddag i rigtigt godt selskab. Den kan du overveje at lytte til. #ISelskabMedQ podcasts.apple.com/dk/podcast/i...
podcasts.apple.com
Med Hella Joof, Maria Yde og Jens Lundgren
Podcast Episode · I selskab med Q · 07/03/2025 · 1h 15m
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Jens Lundgren @profjlundgren.bsky.social · 03/03/2025
H5N1 disease in humans. App 40 cases from USA reported. Most had mild symptoms mainly involving tge upper respiratory tract abd conjunctiva. www.nejm.org/doi/full/10....
nejm.org
Highly Pathogenic Avian Influenza A(H5N1) Virus Infections in Humans | NEJM
Highly pathogenic avian influenza A(H5N1) viruses have caused widespread infections in dairy cows and poultry in the United States, with sporadic human cases. We describe characteristics of human A...
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European Commission @ec.europa.eu · 24/02/2025
603,628 KM² 🇺🇦🇪🇺
Shape of Ukraine's territory in yellow, representing pre-war times, on a dark blue background. Above it, the text 'Courage has a name' is written. Inside the shape, 'Ukraine' is written in dark blue. The EU logo is in the bottom right corner, and #StandWithUkraine is in the bottom left corner.
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Jens Lundgren @profjlundgren.bsky.social · 23/02/2025
Fair position
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The Kyiv Independent @kyivindependent.com · 23/02/2025
⚡️Zelensky won't sign natural resource deal that 'will be paid by 10 generations of Ukrainians.' Zelensky said that he will not recognize the $500 billion request since it vastly outweighs the $100 billion the U.S. has sent in aid to Ukraine.
kyivindependent.com
Zelensky won't sign natural resource deal that 'will be paid by 10 generations of Ukrainians'
President Volodymyr Zelensky pushed back at the U.S.’ demand for a $500 billion deal for its natural resources, saying that the U.S.’s aid grants are not debts, during the Ukraine: Year 2025 forum in ...
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Jens Lundgren @profjlundgren.bsky.social · 15/02/2025
HIV in Africa: a quick guide by prof Andrew Phillips, UCL. Bottom line: delicate situation that quickly can deteriorate again if ongoing problems are interrupted. Please share. Thanks youtu.be/DXdgsC8bDJk?...
youtu.be
Quick guide to effects HIV interventions have been having in Africa
YouTube video by Andrew Phillips
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Jens Lundgren @profjlundgren.bsky.social · 13/02/2025
Hi Pete, hope you’re ok - just remember not to spill the beans- I know you did so today and yesterday and you now realize it negative impact incl it sort of placed at lot of countries and folks at a disadvantage. So better not do that again. Thanks,
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Paul Sax @paulsaxmd.bsky.social · 06/02/2025
After hearing from two of my colleagues in Africa who work with USAID/PEPFAR, and the consequences already of recent events, I had to write this. So sad. And so pointless! #IDSky blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org
Could This Be the End of PEPFAR?
Short email from a longtime colleague, working in Africa at a PEPFAR site: Without USAID, PEPFAR is essentially dead. I got chills reading this. PEPFAR, the abbreviation for the President’s Emergency ...
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Jwst Feed @jwstfeed.bsky.social · 06/02/2025
Clearest image of Mars ever taken. 🔭 🧪
A round, rusty orange planet against the blackness of space. The surface is a mix of lighter and darker orange areas, with some darker markings that look like smudges or streaks. There's a lighter, whitish patch at the top and bottom, which are the polar ice caps.
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IDSA @idsainfo.bsky.social · 06/02/2025
CDC has issued a Health Alert Network advisory about a recently confirmed outbreak of Ebola disease in Uganda caused by the Sudan virus. Read the full advisory that includes CDC’s recommendations, testing, and biosafety considerations:
buff.ly
Health Alert Network (HAN) - 00521 | Ebola Outbreak Caused by Sudan virus in Uganda
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Jens Lundgren @profjlundgren.bsky.social · 30/01/2025
Treatment of rifampicin-resistent fluoquinilone susceptible TB: relevant although small sample study www.nejm.org/doi/full/10....
nejm.org
Oral Regimens for Rifampin-Resistant, Fluoroquinolone-Susceptible Tuberculosis | NEJM
For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis. The advent of new drugs to treat tuberculosis and enhanced funding now p...
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Jens Lundgren @profjlundgren.bsky.social · 30/01/2025
Excellent overview of the Mpox endemic (although at an increasing trend over time) in Africa www.nejm.org/doi/full/10....
nejm.org
Evolving Epidemiology of Mpox in Africa in 2024 | NEJM
For decades after the identification of mpox in humans in the Democratic Republic of Congo (DRC) in 1970, the disease was largely confined to the rural areas of Central and West Africa and thus did...
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Jens Lundgren @profjlundgren.bsky.social · 26/01/2025
BBC: it’s not correct! He argued that it is for safety reasons but US has and have had access to Greenland since 1951 - so the good question is what the real reason is ? To propose that US is now suddenly Greenlands best friend is naive at best. bbc.com/news/article...
bbc.com
Donald Trump says he believes the US will 'get Greenland'
The president told reporters the island's 57,000 residents "want to be with us".
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Jens Lundgren @profjlundgren.bsky.social · 25/01/2025
This is how we see the threat from US presently www.facebook.com/share/r/19yC...
facebook.com
Redirecting...
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Jens Lundgren @profjlundgren.bsky.social · 25/01/2025
t.co/jS8rNc8aji
t.co
https://on.ft.com/4gZt1Hr
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Jens Lundgren @profjlundgren.bsky.social · 19/01/2025
This is not funny anymore- hope US friends realize what impact this has on relationships.
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Jens Lundgren @profjlundgren.bsky.social · 15/01/2025
Serious COVID-19: we have studied reasons and impact from developing lymphopenia. link.springer.com/epdf/10.1186...
link.springer.com
Blood absolute lymphocyte count and trajectory are important in understanding severe COVID-19
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Jens Lundgren @profjlundgren.bsky.social · 11/01/2025
Rsik of Mpox outside of Africa: a review by Eskild Petersen, Lone Simonsen et al. www.ijidonline.com/article/S120...
ijidonline.com
Possible scenarios for the spread of mpox outside the endemic focus in Africa
Over the past two years, mpox has twice been declared a “Public Health Emergency of International Concern”, PHEIC by the World Health Organization (WHO). In 2022, it was in response to a global outbreak of a new clade IIb primarily among men who have sex with men (MSM), ultimately with >100,000 cases reported worldwide centered in Europe and the US [1]. In August 2024, it was in response to a complex outbreak originating in the Democratic Republic of the Congo, DRC, and many fold increase in mpox cases caused by the original central African clade I variant (now designated Ia), but also the emergence of a human-to-human transmitted clade Ib that has since spread to neighboring countries [2].
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Tom Peacock @peacockflu.bsky.social · 07/01/2025
Really proud to share our preprint describing early adaptation of H5N1 to US dairy cattle, and showing how these mutations enhance the ability of the virus to infect other mammals, such as pigs and humans. With @influenzal.bsky.social @vidhid.bsky.social @drclairesmith.bsky.social and many more!
biorxiv.org
Polymerase mutations underlie adaptation of H5N1 influenza virus to dairy cattle and other mammals.
In early 2024, an unprecedented outbreak of H5N1 high pathogenicity avian influenza was detected in dairy cattle in the USA. The epidemic remains uncontrolled, with spillbacks into poultry, wild birds...
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Jens Lundgren @profjlundgren.bsky.social · 09/01/2025
One of the technicaæ products from the @DNRF award to @cphiv to form a center of excellence @persimune to develop precision medicine is now out as a preprint. Congratulations to Ramtin and Maya et al. arxiv.org/abs/2501.04547
arxiv.org
Medical artificial intelligence toolbox (MAIT): an explainable machine learning framework for binary classification, survival modelling, and regression analyses
While machine learning offers diverse techniques suitable for exploring various medical research questions, a cohesive synergistic framework can facilitate the integration and understanding of new app...
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Jens Lundgren @profjlundgren.bsky.social · 08/01/2025
The Western-Eastern European Partnership Initiative on HIV, viral hepatitis, and tuberculosis (WEEPI) Foundation has launched a new open call for proposals for research projects on improving prevention, testing and care for HIV, viral hepatitis, and TB. weepi.org/call-for-pro.... #WEEPI
weepi.org
WEEPI
Standard
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Jens Lundgren @profjlundgren.bsky.social · 07/01/2025
Sorry but this is how the US is now threatening close allies - never thought in my life to hear this!
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Jens Lundgren @profjlundgren.bsky.social · 07/01/2025
Ebloa: confirmation af ring vaccination preventive effect with onset 10 days after vaccination and within 21 days after symptom onset effect of index case www.nejm.org/doi/full/10....
nejm.org
Ebola Outbreak Response in the DRC with rVSV-ZEBOV-GP Ring Vaccination | NEJM
At the beginning of the 2018–2020 outbreak of Ebola virus disease (EVD) in eastern Democratic Republic of Congo (DRC), no vaccine had been licensed. However, cluster-randomized evidence from Guinea...
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Jens Lundgren @profjlundgren.bsky.social · 07/01/2025
Bedquiline appears to be effective also against leprozy as indicated in this 9 cases series. www.nejm.org/doi/full/10....
nejm.org
Bedaquiline Monotherapy for Multibacillary Leprosy | NEJM
Standard multidrug therapy for leprosy may be associated with severe side effects, which add to the stigma and discrimination that affect persons with the disease. In addition, the threat posed by ...
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Jens Lundgren @profjlundgren.bsky.social · 28/12/2024
In danish TV2 news at 11:10am today on this👇topic
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Jens Lundgren @profjlundgren.bsky.social · 28/12/2024
H5N1 in birds cows and a few humans: A fascinating read studying the potential for sialic receptor switch from 2,3 (avian) to 2,6 (human). It all deals with a few codons around 226 i the HA protein. www.science.org/doi/10.1126/...
science.org
A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors
In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-h...
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Jens Lundgren @profjlundgren.bsky.social · 19/12/2024
Erich Tusch defending his PhD these at the #PanumInstitute @KU. Assessors are professors Nina Weiss, Birgit Grund & Ole Søgaard. Well done Erich.
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Dr. Jack Brown @drjackbrown.bsky.social · 08/12/2024
"You may say I'm a dreamer, but I'm not the only one."
John Lennon, playing guitar, studio recording, circa 1969
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Jens Lundgren @profjlundgren.bsky.social · 08/12/2024
Relevant to consider
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Jens Lundgren @profjlundgren.bsky.social · 07/12/2024
Evolving story re influenza A H5/N1 www.nih.gov/news-events/...
nih.gov
Single mutation in H5N1 influenza surface protein could enable easier human infection
NIH-funded study finds risk of human infection continues to remain low.
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Jens Lundgren @profjlundgren.bsky.social · 02/12/2024
Concerning
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Jens Lundgren @profjlundgren.bsky.social · 22/11/2024
Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants - The Lancet www.thelancet.com/journals/lan...
thelancet.com
Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants
In most countries, especially in low-income and middle-income countries, diabetes treatment has not increased at all or has not increased sufficiently in comparison with the rise in prevalence. The bu...
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Jens Lundgren @profjlundgren.bsky.social · 22/11/2024
Efficacy and safety of prostate radiotherapy in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design - The Lancet www.thelancet.com/journals/lan...
thelancet.com
Efficacy and safety of prostate radiotherapy in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design
Combining radiotherapy with standard of care plus abiraterone improves radiographic progression-free survival and castration resistance-free survival, but not overall survival in patients with low-vol...
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Jens Lundgren @profjlundgren.bsky.social · 21/11/2024
Interested in whether HEPA filsters work (pr not)- read this 👇 open.substack.com/pub/alasdair...
open.substack.com
How to not be completely wrong about air filters
A new RCT of HEPA filters for residential care homes gets heads spinning
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Jens Lundgren @profjlundgren.bsky.social · 21/11/2024
Think I have published papers within these themes 👇. Is trying to be innovative though. Funny.
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Tatiana Prowell, MD @tmprowell.bsky.social · 20/11/2024
In a prospective study, people w/ #COVID19 infection breathed & vocalized (sang bday song or yelled “Go Terps!”) into a machine unmasked & in diff types of mask, & exhaled virus was measured. The winner: N95 duckbill-style mask, which blocked 98% of virus. #MedSky #IDSky t.co/2uiIBA4ahW
t.co
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00192-0/fulltext
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