iiinova — where your digital self keeps evolving

Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 7h

(1) EN: CFTR modulators have transformed care for people with Cystic Fibrosis (CF). Using high-throughput screening, researchers identified small-molecule correctors and potentiators that target specific defects in CF-causing variants.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 07/10/2026

(1) EN: Precision medicine is transforming respiratory care by making it more personalized, moving beyond broad disease labels to understand patients through biomarkers, endotypes, and treatable traits.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 06/10/2026

(1) EN: October is Primary Ciliary Dyskinesia (PCD) Awareness Month. PCD is a rare genetic condition in which cilia don’t beat properly, often leading to chronic lung infections, bronchiectasis, and, in some cases, situs inversus. Because testing is limited, diagnosis can take a long time.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 05/10/2026

(1) EN: Coffee may support your lung health more than you might expect. A dose-response study found that caffeine in coffee acts as a mild bronchodilator, improving FEV1 in people with asthma, though it is only about 40% as potent as theophylline.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 04/10/2026

(1) EN: Coffee breaks are more than downtime; they are welcoming spaces for scientific exchange. In the lab, isolation can breed stagnation; over coffee, failures, early-stage ideas, and doubts become shared puzzles to explore together.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 03/10/2026

(1) EN: October is Healthy Lung Month 2026. Our lungs work nonstop… So give them the care they deserve! Quit smoking or vaping, keep your home well-ventilated, stay active, and avoid secondhand smoke.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 02/10/2026

(1) EN: Every breath is a gift we often take for granted… until breathing becomes difficult! Today, we celebrate World Oxygen Day (O–2), the unseen element that sustains every cell in our bodies and every heartbeat.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 02/10/2026

(1) EN: The definitions of acute respiratory distress syndrome (ARDS) have evolved significantly since 1967, when Ashbaugh first described the syndrome clinically. In 1994, experts established a standard diagnostic approach based on blood oxygen levels.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 01/10/2026

(1) EN: In 1989, three Science papers identified the Cystic Fibrosis (CF) gene using complementary approaches: 1) chromosome walking and jumping mapped the locus to chromosome 7; 2) cDNA cloning revealed a ~6,500-nucleotide transcript coding a protein with 2 transmembrane and 2 ATP-binding domains;

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 30/09/2026

(1) EN: A recent study highlights that, despite decades of progress in reducing chronic respiratory disease (CRD) mortality, the burden remains substantial, with increasing concentration among older people and in certain regions.

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Pulmonary & Integrated Molecular Reseach @primrlab.bsky.social · 29/09/2026

(1) EN: Respiratory diseases are responsible for millions of deaths every year, and their burden is felt across every income group. Deaths from lung cancer and COPD are rising, while lower respiratory infections remain a persistent threat.

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