Doctors say IVF technology developed by Gameto, cofounded by Under 30 alumna Dina Radenkovic, has serious potential. Now it’s finally coming to market.

FAESM: A Drop-in Efficient Pytorch Implementation of ESM - pengzhangzhi/faesm

The development of macrocyclic binders to therapeutic proteins has typically relied on large-scale screening methods that are resource-intensive and provide little control over binding mode. Despite c...

Aberrant activation of Wnt signaling results in unregulated accumulation of cytosolic β-catenin, which subsequently enters the nucleus and promotes transcription of genes that contribute to cellular p...

SaLT&PepPr is a protein language model that isolates peptidic motifs from the binding interfaces of target-interacting partner sequences. These peptides are fused to an E3 ligase domain to generat...

Target proteins that lack accessible binding pockets and conformational stability have posed increasing challenges for drug development. Induced proximity strategies, such as PROTACs and molecular...