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prachi-richa.bsky.social

@prachi-richa.bsky.social

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prachi-richa.bsky.social @prachi-richa.bsky.social · 14/08/2026

Excited to share our new publication!🎉 A huge thank you to everyone involved, colleagues and all our collaborators who contributed along the way. #NotchSignaling #DevelopmentalBiology #Neurogenesis #CellBiology #Drosophila #CellFate www.cell.com/current-biol...

Notch-mediated lateral inhibition is shaped by morphological differences to reinforce bias toward signal-sending or -receiving roles

Richa et al. show that Notch signaling and cell mechanics work together to ensure the robust selection of a single neural precursor that never initiates Notch-dependent transcription. One cell is bias...

prachi-richa.bsky.social @prachi-richa.bsky.social · 16/06/2026

www.biorxiv.org/content/10.6...

Notch mediated lateral inhibition is shaped by morphological differences to reinforce bias toward signal-sending or receiving roles

During neurogenesis, neuroblasts are selected from proneural-competent cells through lateral inhibition, a process controlled by the evolutionarily conserved Notch signalling pathway. By tracking tran...