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PPID Journal

@ppidjournal.bsky.social
1.3K followers 1.5K following 57 posts

Infectious Disease Journal for everyday physicians. Written by practicing doctors with articles focusing on clinical practice. #IDSky #MedSky www.ppidjournal.com

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PPID Journal @ppidjournal.bsky.social · 20/09/2026
When does HIV proviral DNA matter clinically? Learn when archived resistance patterns make a difference to your clinical practice and when you should look for them. 👇 www.ppidjournal.com/doi10-55636-...
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HIV Proviral DNA: Clinical Applications, Drug Resistance, and the HIV Reservoir - Private Practice Infectious Disease
Antiretroviral therapy has rendered HIV a manageable chronic infection, but integrated proviral DNA within long-lived CD4+ memory T cells persists indefinitely and constitutes both a barrier to cure…
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PPID Journal @ppidjournal.bsky.social · 18/09/2026
20 yo woman with PMH atopic dermatitis on dupilumab presents with 3 months of headaches, 3 wks of diplopia, blurred vision and CXR shows R sided pneumonia. CSF with OP 35, 2971 WBC (71% lymphs), protein 134, glucose neg. What is the diagnosis? www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 07/09/2026
Glucocorticoids are critical adjunctive strategies in combating infections. But when and where? A new PPID review lays out the evidence for adjunctive glucocorticoids across a variety of infections. Check it out here! www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 23/08/2026
66 yo woman w/ PMH RA on etanercept p/w 2 wk malaise, fevers, LUQ abdominal tenderness, splenomegaly with multiple subcentimeter hypodense splenic lesions with below labs. Prelim work up below. What is dx? Click here to find out 👉https://www.ppidjournal.com/doi10-55636-ppid06030014/
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PPID Journal @ppidjournal.bsky.social · 23/08/2026
66 yo woman w/ PMH RA on etanercept p/w 2 wk malaise, fevers, LUQ abdominal tenderness, splenomegaly with multiple subcentimeter hypodense splenic lesions with below labs. Prelim work up below. What is dx? Click here to find out 👉https://www.ppidjournal.com/doi10-55636-ppid06030014/
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PPID Journal @ppidjournal.bsky.social · 21/08/2026
Secondary immunodeficiencies are far more common than primary ones. Check out this new review that covers the full etiologic spectrum (infection, malnutrition, malignancy, splenectomy, iatrogenic causes) and how to evaluate & manage at-risk patients. www.ppidjournal.com/doi10-55636-...
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Secondary Immunodeficiencies: Clinical Immunology for Infectious Disease Specialists - Private Practice Infectious Disease
Secondary immunodeficiencies (SIDs) are acquired disorders of immune function arising from extrinsic insults to an otherwise intact immune system. Unlike primary immunodeficiencies, which are heritabl...
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PPID Journal @ppidjournal.bsky.social · 06/08/2026
80 yo man with PMH MDS (on azacitadine) p/w cough x 19 mo, CT chest shows mucus plugging, bronchiectasis and bronchitis shows allergic mucin, abundant eos and fungal hyphal elements. WBC 5.3, 37% eos (absolute 1961), IgE 1949. What is the diagnosis? www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 05/08/2026
👂 New case report: a 49-year-old with progressive hearing loss and tinnitus, initially chalked up to noise exposure - turned out to be late-onset otosyphilis. Read why this rare, easily-missed diagnosis deserves a high index of suspicion. Check it out: 🔗
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Late-Onset Otosyphilis: A Case Study of Diagnostic Delay - Private Practice Infectious Disease
Otologic pathology is a well-known, though potentially underdiagnosed, complication of syphilis. While it is most commonly considered a manifestation of early latent or secondary syphilis, otologic symptoms...
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PPID Journal @ppidjournal.bsky.social · 03/08/2026
Now that the recent hantavirus outbreak aboard the MV Hondius appears to be over, it’s a good time to look back at what we know. This review covers ANDV’s rare person-to-person spread, superspreader dynamics, & PPE guidance for clinicians. 🔗
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Hantavirus: Update on Outbreaks from the Four Corners to the MV Hondius - Private Practice Infectious Disease
The two forms of hantavirus infection include Old World, characterized by hemorrhagic fever with renal syndrome (HFRS), and New World, manifested by hantavirus pulmonary syndrome (HPS). In Chile and Argentina,...
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PPID Journal @ppidjournal.bsky.social · 31/07/2026
How do we solve our ID recruitment crisis? Dr. Kam Sidhwa’s new article shows private practices how to fix this: transparent pay, income diversification, and physician-led recruitment that sells culture, not just paperwork. 🔗
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Recruiting Infectious Disease Physicians: A Deepening Crisis and a Path Forward - Private Practice Infectious Disease
The infectious disease (ID) physician workforce faces a recruitment crisis of growing severity. A persistent compensation gap, escalating medical student debt, limited pre-fellowship exposure, and the...
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PPID Journal @ppidjournal.bsky.social · 10/07/2026
#IDsky West Nile, yellow fever are commonly associated with encephalitis, but did you know the neurotropic nature of other arboviruses, including dengue and chikungunya? New review of neurological complications of arboviral infections here:
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Neurological Complications of Arboviral Infections - Private Practice Infectious Disease
Arboviral infections represent an expanding global public health threat, with increasing recognition of their neurological complications. Dengue, chikungunya, Zika, yellow fever, and West Nile viruses...
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PPID Journal @ppidjournal.bsky.social · 07/07/2026
A practical framework for CVID, IgG subclass deficiency, and specific antibody deficiency: how to tell them apart and manage each in adult patients with recurrent infections. #IDsky
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Humoral Immunodeficiency in Adults: Common Variable Immunodeficiency, IgG Subclass Deficiency, and Specific Antibody Deficiency: A Comprehensive Clinical Review - Private Practice Infectious Disease
Humoral immunodeficiencies, particularly common variable immunodeficiency, IgG subclass deficiency, and specific antibody deficiency, represent the most clinically significant primary antibody disorders…
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PPID Journal @ppidjournal.bsky.social · 04/07/2026
#IDsky What makes a private practice group successful? It starts with leadership, which is a skill, represented by a set of behaviors that must be actively and consistently performed. Read about the cornerstone qualities of what makes an effective leader.
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Leadership and Group Structure for Private Practice Infectious Disease Physicians - Private Practice Infectious Disease
Private practice infectious disease (ID) groups face a distinctive set of organizational challenges that differ substantially from those confronting academic or hospital-employed physicians. Physician...
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PPID Journal @ppidjournal.bsky.social · 03/07/2026
#IDx 24 yo man p/w f/c, facial & nasal swelling after scratching inside of his nose. Exam revealed nasal swelling, furuncles, erythema, periorbital swelling & proptosis. Blood cx w/ MSSA (persistently +), MRV w/bilateral cavernous sinus thrombosis. How do you tx?
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When Standard Therapy Is Not Enough: Invasive MSSA Bacteremia with Cavernous Sinus Thrombosis and Mycotic Aneurysm Requiring Salvage Beta-Lactam Therapy - Private Practice Infectious Disease
Methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia is commonly treated with beta-lactam antibiotics, including cefazolin and antistaphylococcal penicillins. Although cefazolin is supported...
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PPID Journal @ppidjournal.bsky.social · 01/07/2026
#IDsky 42 yo woman who presents with pelvic abscess 6 wks post TAH-BSO. Extension of abscess to adjacent bowel loops noted. What is the pathogen and how do you tx? www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 11/04/2026
Pt presents with 2 wk headaches, blurred vision, polyuria, polydipsia, Na 121. Found to have panhypopituitarism from mass involving pituitary gland. CT chest and skin lesion below. What is the diagnosis? www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 10/04/2026
What happens when a 79 year old woman wrestles a badger to protect her dog? What do you get from a badger bite? Read all about this fascinating case report here! www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 08/04/2026
Curbside consults are a daily reality in ID practice - but are we thinking carefully about the risk? This article examines the clinical, ethical and legal dimensions of curbside consults and gives you practical strategies to minimize liability
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Informal (“Curbside”) Consultations in Infectious Disease Practice: Advantages, Disadvantages, and Liability Issues - Private Practice Infectious Disease
Informal consultations are discussions between healthcare professionals outside of formal clinical settings. The process involves a physician directly involved in a patient’s care requesting informal…
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PPID Journal @ppidjournal.bsky.social · 22/12/2025
Clinical educators - this one’s for you! A pragmatic approach to teaching ID in a busy private practice - actionable strategies to boost engagement and learning!
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Teaching Infectious Diseases in the Context of a Busy Private Practice: A Pragmatic Framework for Clinician Educators - Private Practice Infectious Disease
Abstract Teaching infectious diseases (ID) in private practice is inherently constrained by multiple external and internal factors, including time scarcity, documentation burden, and financial…
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PPID Journal @ppidjournal.bsky.social · 21/12/2025
Malpractice litigation is a reality for many clinicians - even in ID. This article explains the anatomy of a lawsuit and shares proves risk reduction strategies to help protect your practice and your patients 🩺 💡 www.ppidjournal.com/doi10-55636-...
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An Introduction to Medical Negligence Litigation: Anatomy of a Lawsuit and Risk Reduction Strategies - Private Practice Infectious Disease
Medical negligence litigation poses substantial economic and emotional concerns for healthcare providers, including infectious disease specialists. Even in relatively low risk specialties such as infe...
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PPID Journal @ppidjournal.bsky.social · 14/10/2025
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PPID Journal @ppidjournal.bsky.social · 11/10/2025
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PPID Journal @ppidjournal.bsky.social · 05/10/2025
#IDsky New case report: Strep canis bacteremia in a COVID19 patient - a rare zoonotic infection with potential serious implications.
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Streptococcus canis Bacteremia in a Patient Co-Infected with COVID-19: A Case Report - Private Practice Infectious Disease
Streptococcus canis, primarily recognized as a commensal pathogen in animals, has emerged as a potential cause of human infections, including bacteremia. We present a case of S. canis bacteremia in…
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PPID Journal @ppidjournal.bsky.social · 05/10/2025
#IDsky 56 yo retired Desert Storm veteran p/w 1 month of fevers, 2 wks of headaches, 4 d of floaters & progressive loss of central vision. Hx of fostering dogs🐕 & 🐈. Fundoscopic exam: optic nerve disc edema w/ blurred disc margins. How would you tx? *click👇 www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 03/10/2025
#IDsky Curious about the differences between FMTs for recurrent C. Diff? Which therapy suits your patient best? Explore the 4 options: Rebyota, Vowst, VE303, and CP101 here. www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 02/10/2025
#IDsky Do you know the faux pas of an ID consultation? Don’t make these mistakes! Here are 8 steps to a successful ID consultation www.ppidjournal.com/doi10-55636-...
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The Art and Science of Infectious Disease Consultation - Private Practice Infectious Disease
Infectious disease is a cognitive specialty, procedurally represented by the consultation. Done correctly, a consultation is a powerful tool that can change physician behavior, strengthen critical relationships,...
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PPID Journal @ppidjournal.bsky.social · 02/07/2025
#IDsky Learn key strategies on how to build a thriving Infectious Disease Private Practice here! www.ppidjournal.com/doi10-55636-...
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Building a Thriving Infectious Disease Practice: Key Strategies for Financial Success and Sustainability - Private Practice Infectious Disease
This article summarizes key characteristics of a successful private practice group in Infectious Disease based on the experience of Metro Infectious Disease Consultants.
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PPID Journal @ppidjournal.bsky.social · 28/06/2025
#IDsky 22 yo man w/ PMH bicuspid aortic valve & recent dental work presents with fever, myalgias and Strep gordonii bacteremia. Echo shows this ⬇️. What is the diagnosis? *Click here to find out* www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 27/06/2025
#IDsky 50 yo man with poorly controlled DM, HTN p/w Group B strep bacteremia and the below findings. What is the diagnosis? *Click here to find out* www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 26/06/2025
#IDsky Read this fascinating case of myopericarditis caused by Salmonella! Pt presented with chest pain, fever, diffuse ST elevation on EKG, and trop elevation with diffuse enhancement of cardiac wall with myocardial edema. www.ppidjournal.com/doi10-55636-...
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A Rare Case of Salmonella Myopericarditis in an Athlete: Diagnosis by Stool Polymerase Chain Reaction (PCR) - Private Practice Infectious Disease
Introduction Myocarditis, a potentially life-threatening disease characterized by inflammatory infiltration of the myocardium and/or degeneration of myocardial tissue, has many potential infectious...
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PPID Journal @ppidjournal.bsky.social · 26/06/2025
#IDsky Read this fascinating case of myopericarditis caused by Salmonella! Pt presented with chest pain, fever, diffuse ST elevation on EKG, and trop elevation with diffuse enhancement of cardiac wall with myocardial edema. www.ppidjournal.com/doi10-55636-...
ppidjournal.com
A Rare Case of Salmonella Myopericarditis in an Athlete: Diagnosis by Stool Polymerase Chain Reaction (PCR) - Private Practice Infectious Disease
Introduction Myocarditis, a potentially life-threatening disease characterized by inflammatory infiltration of the myocardium and/or degeneration of myocardial tissue, has many potential infectious...
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PPID Journal @ppidjournal.bsky.social · 19/04/2025
#IDsky Which pts undergoing abdominal surgery should receive empiric anti-fungal therapy? A. Any abdominal surgery B. Septic shock C. Pts w/ recent abdominal surgery & recurrent gastrointestinal perforations/anastomotic leakages D. Pts w/hx of prior abx exposure www.ppidjournal.com/quiz/candida/
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Board Review | Candida
In which patient population undergoing abdominal surgery, should empiric anti-fungal therapy be given? A) Any abdominal surgery B) Septic shock C) Patients with recent abdominal surgery and recurrent ...
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PPID Journal @ppidjournal.bsky.social · 31/03/2025
#IDsky Severe malaria meets sickle cell anemia: A complex case where P. Falciparum & ACS challenge both dx & treatment. Successful recovery with artesunate & RBC exchange transfusion highlight importance of timing concurrent prompt management! www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 30/03/2025
#IDsky 68 yo PWH on biktarvy, CD4 650, undetectable VL, recent dx of bladder cancer, bilateral nephrostomies, p/w PURPLE urine (see picture). Why is the urine purple? *click to find out* www.ppidjournal.com/quiz/march-2...
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PPID Journal @ppidjournal.bsky.social · 29/03/2025
#IDsky 48 yo man p/w fever, chills, malaise, jaundice, throat swelling, & exudative pharyngitis. AST 299, ALT 528, Bili 8.3. Read about this interesting case of primary EBV hepatitis & how early intervention made the difference! *click to read* www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 22/03/2025
#IDsky 73 yo man p/w chronic oral lesions, odynophagia, mildly enlarged cervical LAD, 20 lb weight loss and RUL nodule. What is the diagnosis and how did he do? *Click to find out* www.ppidjournal.com/doi10-55636-...
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PPID Journal @ppidjournal.bsky.social · 21/03/2025
#IDBoardReview 75 yo woman w/ PMH HTN, DM p/w 4d abd pain, f/c, n/v/diarrhea after eating raw crab 48 hours earlier. Blood cx grows out GNRs, what is dx? A. Enteropathogenic E. coli B. Haemophilus influenza C. Vibrio cholera non-O1/non-O139 strain D. PsAR www.ppidjournal.com/quiz/vibrio/
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PPID Journal @ppidjournal.bsky.social · 20/03/2025
#IDBoardReview 35 yo man p/w painless ulcer in R groin following unprotected sex 1 wk prior w/new partner. Pt w/ hx syphilis 5y ago. FTA Ab+, RPR-. What next? A. - RPR, no need to tx B. Tx empirically, rpt RPR in 4 wks C. 👀 for alternative dx D. B & C www.ppidjournal.com/quiz/syphilis/
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PPID Journal @ppidjournal.bsky.social · 19/03/2025
#IDBoardReview 49 yo woman with PMH relapsed multiple myeloma tx with Isatuximab, pomalyst, & dex p/w 3 d of fever, AMS, dense LLL pna . What is the dx? A. HSV pna B. Bacterial pna w/encapsulated org C. Reactivation TB D. Aspergillosis www.ppidjournal.com/quiz/multipl...
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Board Review | Multiple Myeloma
1. 49 yo woman with PMH relapsed refractory IgG Lamba Multiple Myeloma, most recently treated with Isatuximab, Pomalyst, dexamethasone presents to the hospital with 3 days of altered mental status,…
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PPID Journal @ppidjournal.bsky.social · 18/03/2025
60 yo patient with PMH schizoaffective disorder p/w hypertrophic growths on hands and feet. WBC 6.4, 6.6% eos. What is the diagnosis and how would you treat this patient? *click to take the quiz* www.ppidjournal.com/quiz/decembe...
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PPID Journal @ppidjournal.bsky.social · 17/03/2025
#IDBoardReview What levels are abnormal in specific antibody deficiency? A. Quantitative immunoglobulins B. IgG subsets C. Response to protein based vaccine D. Response to conjugate vaccines E. Response to polysaccharide antigens
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Board Review | Specific Antibody Deficiency
1. What levels are abnormal in specific antibody deficiency? A. Quantitative immunoglobulins B. IgG subsets C. Response to protein based vaccine D. Response to conjugate vaccinesE. Response to polysaccharide...
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PPID Journal @ppidjournal.bsky.social · 16/03/2025
#BoardReview Which is NOT a criteria for PJI dx according to 2013 IDSA guidelines? A. Sinus tract w/ prosthesis B. ⬆️ WBC w/ ⬆️ PMNs w/in synovial fluid (3K w/80% PMNs) C. + pus near prosthesis intraop D. ≥2 +cx w/ same org (pre-/intraop)
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Board Review | Prosthetic Joint Infections
1. Which of the following is NOT a diagnostic criterion for the definition of PJI according to the IDSA guidelines (2013)? Sinus tract communicating with the prosthesis Elevated WBC with high predominance...
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PPID Journal @ppidjournal.bsky.social · 15/03/2025
#IDBoardReview #Mycobacterium Test your ID knowledge w/ our ID Board Review❓ Bank! Which of the following is NOT a recognized subspecies of M. abscessus? A. abscessus B. bolletii C. massiliense D. chelonae *click here*
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Mycobacterium Abscessus - Private Practice Infectious Disease
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PPID Journal @ppidjournal.bsky.social · 14/03/2025
#IDBoardReview #Measles Test your ID knowledge w/ our ID Board Review❓ Bank! People born before what yr are considered to be immune to measles due to the likelihood of natural infection prior to widespread vaccination? A) 1957 B) 1963 C) 1970 D) 1980
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Measles - Private Practice Infectious Disease
Correct Answer:\u00a0 A) 1957People born before 1957 are often assumed to be immune to measles. This assumption is based on the high likelihood that they were exposed to the measles virus naturally,…
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PPID Journal @ppidjournal.bsky.social · 13/03/2025
#IDBoardReview #Immunodeficiency Test your ID knowledge with our ID Board Review Question Bank! Which of the following antibody concentrations must be normal to qualify for dx of IgG subclass deficiency? A. IgA B. IgM C. IgG D. IgE
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IgG Subclass Deficiency - Private Practice Infectious Disease
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PPID Journal @ppidjournal.bsky.social · 12/03/2025
#IDBoardReview #HIV Test your ID knowledge w/ our ID Board Review ❓Bank! 45 yo man p/w unstable angina, undergoes PCI. His HIV ELISA is +, CD4 100 & VL 250K. If you had to Rx a PI, which would be best? A. Darunavir B. Atazanavir C. Fosemprenavir D. Lopinavir
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HIV - Private Practice Infectious Disease
This question module contains 5 questions related to HIV therapeutics.
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PPID Journal @ppidjournal.bsky.social · 11/03/2025
#IDBoardReview #Encephalitis Test your ID knowledge with our ID Board Review Question Bank! What is NOT one of the minor criteria for the definition of encephalitis A. Fever B. New onset seizure C. Acute mental status change D. CSF WBC ≥ 5 *Click here* www.ppidjournal.com/quiz/encepha...
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Board Review | Encephalitis
What is NOT one of the minor criteria for definition of encephalitis? A) Fever B) New onset seizure C) Acute mental status change D) CSF WBC ≥ 5
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PPID Journal @ppidjournal.bsky.social · 11/03/2025
#IDBoardReview #HepB Test your ID knowledge with our ID Board Review Question Bank! Which of the following is considered the main indicator of previously resolved HBV (HBsAg-, anti-HBc+) A. ⬆️ ALT 2x ULN B. Detectable HBV DNA C. + HBsAg D. A and C E. B and C
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HBV - Private Practice Infectious Disease
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PPID Journal @ppidjournal.bsky.social · 09/03/2025
Prepare for success with our Infectious Disease Board Review Question Bank! 💡 Test your knowledge, sharpen your skills, and ace your exams with a comprehensive set of practice questions.
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Board Review - Private Practice Infectious Disease
All Bacterial Infections Board Review Bone and Joint Infections Immunocompromised Host Travel Medicine Viral Infections Encephalitis Take Quiz HBV Take Quiz HIV Take Quiz IgG Subclass Deficiency Take...
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PPID Journal @ppidjournal.bsky.social · 08/03/2025
Explore the complexities of treating M. abscessus in this article! These are the pharmacy pearls you need to know about each agent as treatment can be challenging. A fantastic reference as a starting point.
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Mycobacterium abscessus - Private Practice Infectious Disease
Mycobacterium abscessus falls into a group of non-tuberculosis mycobacterium, further sub-classified as a rapid-growing mycobacterium. The prevalence of M. abscessus has been increasing over the last…
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