Janne Pott @pottj.bsky.social · 23/09/2026Time off at a nice beach, lots of swimming (fishes, but no jellyfish), and then getting PM that a grant was approved 😁 - what more can you ask for? 020
Janne Pott @pottj.bsky.social · 22/04/2026Now published in CEBP: doi.org/10.1158/1055... In summary: we did not find a significant effect of PCSK9 on BC survival using Mendelian Randomization.doi.orgPCSK9 and Breast Cancer Survival: A Mendelian Randomization StudyAbstractBackground:. Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects lipid metabolism. A recent study identified an association between rs562556 within the PCSK9 gene and breast cancer s... 131
Janne Pott @pottj.bsky.social · 06/10/2025📣Preprint alert - a tricky one, as there are no significant results (and we all know null-results are hard to publish) Do PCSK9 levels affect survival in breast cancer patients? We tried to replicate findings in cell lines and mouse model using 3 Mendelian Randomization approaches, but failed. 185
Janne Pott @pottj.bsky.social · 10/06/2025📣Paper alert! (Spoiler: this is not my usual GenEpi paper 😁 #phylogenetics) How many small trees do you need to define one supertree? Mareike Fischer and I explored this question and defined a subclass of taxon sets that guarantees decisiveness aka one supertree link.springer.com/article/10.1...link.springer.comPerfect Taxon Sampling and Fixing Taxon Traceability: Introducing a Class of Phylogenetically Decisive Collections of Taxon Sets - Bulletin of Mathematical BiologyPhylogenetically decisive collections of taxon sets have the property that if trees are chosen for each of their elements, as long as these trees are compatible, the resulting supertree is unique. Thi... 131