iiinova — where your digital self keeps evolving

Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Congratulations on the publication. We will eventually need to care about all viruses to protect our brains. "Memory impairment was induced by infection with either HSV-1 or HSV-2 wild-type viruses, indicating that the cognitive impairment associated with neonatal infection was not strain-specific"

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Nous avons été informés que le Dr Marc Veldhoen emploie une petite armée de bots et de trolls et nous étions donc préparés à la parade ridicule de quelque chose d'aussi stupide que d'être déclaré mort.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

"However, Long COVID is not a mystery. Research increasingly links the condition and its symptoms to persistent SARS-CoV-2 infection, with evidence showing that the virus can linger in reservoirs for months, or even years, in at least a subset of individuals"

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Bien que l'on sache que le dysfonctionnement mitochondrial est lié à la maladie d'Alzheimer, Parkinson et à d'autres troubles neurologiques, la recherche de nouvelles thérapies visant à protéger ou à restaurer les fonctions cérébrales n'est pas en cours. neurosciencenews.com/mitochondria...

neurosciencenews.com

Mitochondria’s Role in Social Memory May Offer Clues to Brain Disorder - Neuroscience News

Researchers have identified a unique mitochondrial process in CA2 neurons that supports learning, memory, and social recognition.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

"correlation does not equal causation" is unfortunately often used to rebuke new findings, even if zero evidence supports any other explanation. IE: genetics as a cause of neurological diseases, decades after birth is a theory which lacks any correlation and causation. www.mdpi.com/1999-4915/12...

mdpi.com

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?

Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. However, in vulnerable populations, such as newborns, infants, the elderly and immune-compromised individual...

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Ce virologue est (était) une personne différente.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

PINK1 & Parkin, two Parkinson’s disease-related proteins, inhibit the process of formation of mitochondrial-derived vesicles. These vesicles allow the cell to display mitochondrial antigens on the cell’s surface, deregulating this system of communication from the cell to the immune system. 2/2

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

C'est un nom commun. C'était une autre personne.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

This is a pattern. We didn't question Mr. Nirenberg's lack of credentials. We questioned his interpretation that H5N1 is not neuroinvasive from a study that didn't look to determine if H5N1 was neuroinvasive. In response he attacked me personally and blocked our account. bsky.app/profile/gayf...

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Vous supposez que je n'avais pas l'intention de me moquer de lui? Toute la communauté des chercheurs en immunologie se moque de Veldhoen. Ce n'est pas pour rien qu'il a été rejeté dans son pays d'origine et que seul un institut désespérément à la recherche d'un immunologue l'a accepté.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Toute la communauté des chercheurs en immunologie se moque de Veldhoen. Ce n'est pas pour rien qu'il a été rejeté dans son pays d'origine et que seul un institut désespérément à la recherche d'un immunologue l'a accepté.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Il s'agit d'une autre personne différente. Je suis manifestement toujours en vie.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

If Mr. Nirenberg is not an immunologist, Why is Edward Nirenberg offering medical advice?

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Reposted by Dr Pierre Talbot

Betty C. Jung @bettycjung.bsky.social · 11/02/2025

He is so right.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Nous disposons de solutions pharmaceutiques contre la tuberculose et la manière dont nous utilisons ces solutions n'est pas soutenable. Nous aurions dû vacciner des populations entières contre la tuberculose avant qu'elles ne soient victimes d'infections répétées de SRAS. bsky.app/profile/john...

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Le SRAS n'a jamais risqué d'entraîner la mort après une seule infection. Le SRAS possède une adaptation unique de l'immunité humaine qui permet des infections multiples et répétées. La destruction du système immunitaire et les infections opportunistes bactériennes constituent le danger du SRAS.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Marc Veldhoen is a psychopath, not a physician. Social media influencers who are not immunologists and accounts pretending to be immunologists blocked our account and declared us dead. Which is incredibly ironic.

Des comptes qui ont bloqué notre compte.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

Marc Veldhoen est un psychopathe, pas un physicien. Des influenceurs de médias sociaux qui ne sont pas immunologistes et des comptes prétendant être immunologistes ont bloqué notre compte et nous ont déclarés morts. Ce qui est incroyablement amusant.

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Dr Pierre Talbot @pierretalbot.bsky.social · 11/02/2025

L'autre réponse évidente est que quelqu'un se trompe.

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Reposted by Dr Pierre Talbot

Casey Whitaker @alphacentauri53.bsky.social · 11/02/2025

Culling the herd. Eugenics through inaction and neglect. Many governments did the math and decided to let people get a novel virus repeatedly until “the weak” were removed (bonus, no need to pay pensions). Not caring that “novel” means unknown. The impact on our young, our future, is incalculable.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

I retired from direct research but still comment and are included in several studies. Sorry if you are confusing me with someone else.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

The tragedy of abandoning everyone to take individual precautions is underfunded primary care. Without proper access to physicians there is an escalating and incremental cost when any diagnosis and treatment is delayed, especially #LongCOVID. #PublicHealth #EpiSky www.cidrap.umn.edu/covid-19/pri...

cidrap.umn.edu

Primary care less accessible during COVID, but some practice types adapted more easily

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

The next 4-5 years are going to be unhinged. It'll take decades to restore and repair the damage to Public Health.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Has this struck a nerve with the science denying trolls?

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

It's not everyone ... but even when a scientist asks to back up a statement of fact, they are: - not being honest - seeking to waste time - debating a position without backing up their position - without ability to be swayed to consider or accept your position - or they would go find the data.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

I have to assume the joke is on you. Do you have any questions about why the elderly are more vulnerable to HCoV infections or are you just trolling?

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Different person. We cannot explain your fixation.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

10/10 This study underscores the importance of ongoing research into long COVID in kids. The true burden of long COVID in kids is likely higher than reported. Understanding these risks can help improve prevention, management, and care for affected children. #LongCOVIDKids #PediatricHealth

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

9/10 Takeaways: - COVID-19 can lead to prolonged GI issues in kids, even after mild infections. - Clinicians should monitor for symptoms like abdominal pain, diarrhea, and GERD in kids with a history of COVID-19. #PediatricCare #LongCOVIDAwareness

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

8/10 Potential mechanisms: - High ACE2 receptor expression in the gut - Viral persistence in the GI tract - Gut microbiome disruption More research is needed to understand these pathways. #LongCOVID #COVID19Research #GutHealth

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

7/10 What can be done? - Raise awareness about long COVID in kids, even without a documented infection. - Broaden diagnostic criteria to include kids with persistent symptoms. #LongCOVIDKids #Healthcare

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

6/10 Research gaps: Without testing data, we lack a full picture of long COVID in kids. This hinders our understanding of prevalence, risk factors, and long-term outcomes. #ResearchNeeded #Pediatrics

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

5/10 Clinicians face diagnostic uncertainty: without a documented COVID-19 history, it’s harder to attribute symptoms to long COVID. This can lead to misdiagnosis or unnecessary tests. #HealthcareChallenges #LongCOVID

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

4/10 The elimination of widespread SARS-CoV-2 testing creates challenges: - Harder to track long COVID cases - Difficult to identify at-risk kids - Incomplete data for public health planning #SARSTestingMatters #PublicHealth

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

3/10 Without testing, families & clinicians may not connect persistent symptoms (e.g., abdominal pain, fatigue) to a prior COVID-19 infection. This leads to underdiagnosis and delayed care. #LongCOVIDAwareness #PediatricHealth

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

1/10 🧵 New research shows 1.5 million kids with documented COVID-19 face a 25% higher risk of GI symptoms like abdominal pain & diarrhea for up to 2 years. But what about kids who were infected but never tested? Let’s break it down. #LongCOVID #Pediatrics #MedSky www.cidrap.umn.edu/covid-19/aft...

cidrap.umn.edu

After COVID-19, kids more likely to have GI symptoms for up to 2 years

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

There's no vomit or nausea. These are incidences of irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), or functional dyspepsia where the most common symptom will be abdominal pain and discoloured or loose stools. academic.oup.com/cid/advance-...

academic.oup.com

Long-COVID incidence proportion in adults and children between 2020 and 2024

This electronic health record-based study of COVID-19 positive patients across three national research networks found consistent temporal patterns in the i

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Nous nous sommes retirés de la recherche en neuroimmunologie et sur les coronavirus humains, mais nous recevons encore des demandes des révisions. Vous avez des questions? bsky.app/profile/pier...

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Let us know when you google our review and input into recent studies HCoV/Alzheimer's research and declare us undead. bsky.app/profile/pier...

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Hit & Run Respiratory viruses and HCoVs in particular can cause significant accumulation of misfolded proteins in the immuno-naïve regions of the CNS. We don't have a cure for #Alzheimers because we do not have medicine that resolves these fibrinogen. #LongCOVID causes neuroinflammation.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Maybe that's a google search you should have done before you and the others declared me dead. We're going to spend our time searching for #LongCOVID people in search of assistance. Don't bother to let me know if you declare me undead.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

You will notice papers from 2023. Pardon if we feel inadequate to express how one never retires from either the mob, or research review.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Nous nous sommes retirés de la recherche en neuroimmunologie et sur les coronavirus humains, mais nous recevons encore des demandes de révision de publications. Please forgive our poor english answers.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Probiotics can relieve irritable bowel syndrome (IBS). Probiotics would be appropriate if the root cause of IBS, gastroesophageal reflux disease (GERD), or functional dyspepsia has been identified. They should be recommended by a healthcare physician who has ruled out serious underlying conditions.

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Dr Pierre Talbot @pierretalbot.bsky.social · 10/02/2025

Quel est votre parcours professionnel? M. Niremberg prétend que le virus H5N1 n'est pas neuroinvasif. Vous semblez suggérer que le virus qui provoque des lésions du nerf oculaire n'est pas neuroinvasif ? Sauf que nous savons que le virus H5N1 est neuroinvasif depuis que nous l'avons découvert.

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