In 1747 James Lind ran what is widely called the first controlled clinical trial and found the cause for scurvy.
Then he buried it in five paragraphs of a 400-page book and drew the wrong conclusion....
→ substack.com/@pharmahisto...
substack.com
Scurvy: 3500 years of „They almost had it”
The history of scurvy and the discovery of vitamin C