pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 02/04/202518/🔬TROPHY-U-01 Cohort 3 trial safety of sacituzumab govitecan👇 TRAEs led to➡️ ✋SG interruptions in 46% ⬇️SG dose reduction in 39% 🛑SG d/c in 15% @markuseckstein3.bsky.social @amandanizammd.bsky.social #OncSky 101
pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 02/04/202511/Erda. Safety Grade ≥3 TRAEs occurred in 45.9% w erdafitinib & 46.4% w chemo ⚖️Most AEs w erdafitinib manageable w dose modification & best supportive care 🛑Tx d/c rates 8.1% w erdafitinib & 13.4% w chemo #OncSky #BladderCancer 101
pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 02/04/202510/➡️Erdafitinib cont. 👍mOS and mPFS significantly ⬆️in erdafitinib group vs taxane or vinflunine THOR1 trial efficacy results 👇 #OncSky @achoud72.bsky.social @pbarata95.bsky.social @crisbergerot.bsky.social @paulobergerot.bsky.social @alisonbirtle.bsky.social @laurabukavinamd.bsky.social 122
pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 02/04/20257/ IMvigor130 safety results 👇 🎯 Fewer AEs ➡️ withdrawal of any agent in atezo only group 🎯 Most common TRAEs mainly related to chemo ✓ Anemia ✓ Neutropenia ✓ Thrombocytopenia #OncSky 101
pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 02/04/20256/Atezolizumab EMA approved as monotx ✓1L in cisplatin-ineligible + PD-L1 +ve Based on IMvigor 210 & 130 trials 🔬IMvigor 130: ✅mPFS significantly longer in atezo+plat/Gem vs plat/Gem alone 🚫mOS not sign. longer in atezo grps vs plat/Gem alone @oncobellmunt.bsky.social @sandysrimd.bsky.social 101
pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 02/04/20252/ 📸👇COI & CME info👇 Full #CME ℹ️ bit.ly/muc_tw2 1️⃣ Answer Pre-survey 👉 bit.ly/muc_tw2_pre 2️⃣ Review #MedTweetorial👇 3️⃣ claim CME🏆bit.ly/muc_tw2_post #MedTwitter #OncTwitter #gucsm #BladderCancer #MetastaticUrothelialCarcinoma #OncX #CommunityOncology 101
pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 06/12/2024Stayed active during 17-hour flight from SEA->Singapore :-) Looking forward to present TROPiCS04 phase 3 trial data at #ESMOASIA on Dec 7 ~10am local time discussed by Dr. Friedlander @oncoalert.bsky.social @achoud72.bsky.social @erplimackmd.bsky.social @valdesan.bsky.social @fredhutch.bsky.social 172
pgrivasmdphd.bsky.social @pgrivasmdphd.bsky.social · 29/11/2024This is my 1st post in BlueSky wishing Happy Thanksgiving to everyone with health! Best wishes from Vienna! @erplimackmd.bsky.social @achoud72.bsky.social @lauracaba.bsky.social @oncoalert.bsky.social @johngoremd.bsky.social @drnataliagandur.bsky.social @fredhutch.bsky.social @tmprowell.bsky.social 0122
