iiinova — where your digital self keeps evolving

Riccardo Percudani @percud.bsky.social · 05/09/2026

Wrapping up a great #ECCB2026 in Geneva with our poster, presented by Giovanni Merici. Thanks to the organizers for a successful meeting and to everyone who stopped by to discuss our work

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Riccardo Percudani @percud.bsky.social · 01/09/2026

Very interesting Ng’s talk on *predicts cognate pairing of heavy and light immunoglobulin chains at #Eccb2026*

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Riccardo Percudani @percud.bsky.social · 31/08/2026

“We not only have to share data, but also share the benefits of sharing data.” Powerful opening keynote by Jeremy Farrar at #ECCB2026 in Geneva — with no slides.

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Riccardo Percudani @percud.bsky.social · 10/02/2026

Irena Maus (ELIXIR-DE) with Integrating ELIXIR Germany Within the European Infrastructure closes a stimulating Elixir All-Hands meeting in Bari @elixir-it.bsky.social

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Riccardo Percudani @percud.bsky.social · 22/11/2025

A new component of the CatSper ion channel identified! Great collaboration with Jean-Ju Chung (Yale School of Medicine) and Jianping Wu (Westlake University). www.nature.com/articles/s41...

Eukaryotic tree showing coevolution of CatSper subunits

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Riccardo Percudani @percud.bsky.social · 01/08/2025

We used coevolutionary analysis of KEGG networks to identify the gene linked to L-xylulose formation in human metabolism and Garrod's pentosuria. #Bioinformatics #Genomics #Biochemistry Now in PNAS: t.co/iPIhrbUmxz (Preprint: www.researchsquare.com/article/rs-6...)

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Riccardo Percudani @percud.bsky.social · 24/07/2025

Structural variation in human genome based on pangenome analysis. Tobias Marschall at #ISMBECCB2025

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Riccardo Percudani @percud.bsky.social · 23/07/2025

Charlotte Dean on the future of AI-driven drug discovery #ISMBECCB2025 key note

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Erva Ulusoy presenting ProtHGT: protein function prediction using biological knowledge graphs and LLM at #ISMBECCB2025

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Clara De Paolis Kaluza on the past, present, and future of CAFA at #ISMBECCB2025

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Matthias Blum: integrating AI in InterPro. #ismbeccb2025 function COSI

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Erik Sonnhammer nicely presenting the FunCoup database and the complexity of functional networks at the #Ismbeccb2025

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Nicola Bordin: novel domain arrangements but no novel folds in the metagenome billion-scale protein universe. Nicely reported at the #ismbeccb2025

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Paul D. Thomas illustrating the GO annotation as derived from evolutionary modeling at #ismbeccb2025

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Riccardo Percudani @percud.bsky.social · 22/07/2025

The birth and death of protein domains in metazoa presented by Maureen Stolzer at the #ismbeccb2025 functon-evolution section

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Marc Robinson-Rechavi, the funcional divergence of orthologs and paralogs, and the Bgee database at the function-EvolCompBiol section of #ismbeccb2025

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Riccardo Percudani @percud.bsky.social · 22/07/2025

Overton prize James Zou illuminating the future of computational biology in his #ismbeccb2025 keynote on AI agents.

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Riccardo Percudani @percud.bsky.social · 21/07/2025

Adam Gudys presenting at the EvolCompgen section of #ISMBECCB2025 FAMSA2: protein multiple alignment at the protein universe scale

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Riccardo Percudani @percud.bsky.social · 20/07/2025

Janet Thornton introducing John Jumper for the opening keynote at #ismbeccb2025

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Riccardo Percudani @percud.bsky.social · 06/01/2025

Allantoin - In 1800, Vauquelin, together with Buniva, discovered a substance present in cow amniotic fluid but not in that of humans. It was later found in allantoic fluid and named allantoin. Allantoin is the end product of purine degradation in placental mammals, but not in humans and other apes

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Riccardo Percudani @percud.bsky.social · 06/01/2025

Malic acid - Vauquelin confirmed the existence of malic acid, which he isolated from apple juice. This intermediate of the Krebs and glyoxylate cycles was first discovered by Carl Wilhelm Scheele and later named by Antoine Lavoisier after the Latin word for apple, malum.

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Riccardo Percudani @percud.bsky.social · 06/01/2025

Asparagine - In 1806, Louis Nicolas Vauquelin and his assistant Pierre Jean Robiquet isolated asparagine (Asn, N) in crystalline form. As the first of the 20 universal amino acids to be identified, asparagine was named after its source: asparagus juice.

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Riccardo Percudani @percud.bsky.social · 06/01/2025

Louis Nicolas Vauquelin (1763–1829), a French chemist, is best known for discovering chromium and beryllium. However, his contributions to biochemistry are often overlooked—he was the first to isolate several iconic metabolites. 1/4

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Riccardo Percudani @percud.bsky.social · 14/11/2024

Pierre-Régis Burgel presenting the keynote speech at the 22nd convention of investigators in Cystic Fibrosis.

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Riccardo Percudani @percud.bsky.social · 30/10/2024

Our #bioinformatics course assistants love using ChatGPT visuals in the computer lab exercises. I found this #BLAST visual quite punching!

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Riccardo Percudani @percud.bsky.social · 16/07/2024

2024 ISCB Innovator Award recipient, Dr. Sui-In Lee, concludes the #ISMB2024 congress with a powerful message: the researchers' goal is not to publish in prestigious journals, but to push the boundaries of human knowledge.

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Riccardo Percudani @percud.bsky.social · 16/07/2024

Thomas Lengauer explains the behind the doors of publishing in Bioinformatics Advances @BioinfoAdv, the open access journal of the International Society for Computational Biology. #ISMB2024

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Riccardo Percudani @percud.bsky.social · 16/07/2024

Alex Bateman discusses fair and unfair uses of generative AI and LLMs in scientific publishing at #ISMB2024. Unmissable if one want to use GTP for assistance.

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Riccardo Percudani @percud.bsky.social · 15/07/2024

Yannis Nevers nicely reporting at #ISMB2024 about OMArk, a software for genome quality assessment -a fundamental issue for downstream analysis.

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Riccardo Percudani @percud.bsky.social · 15/07/2024

Burkhard Rost introducing with energy and clarity VespaG: fast and accurate protein variant fitness prediction using Language Models. (the G stands for GEMME). VarI-COSI #ISMB2024

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Riccardo Percudani @percud.bsky.social · 15/07/2024

ISCB Overton Award recipient Martin Steinegger @thesteinegger discusses his cutting-edge algorithms and reveals his unconventional career journey, however full of famous mentors.

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Riccardo Percudani @percud.bsky.social · 14/07/2024

Mahta Mehdiabadi nicely presenting the work of @BioComputingUP on disordered protein prediction at #ISMB2024

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Riccardo Percudani @percud.bsky.social · 14/07/2024

Fascinating Gonzalo Parra talk about protein local frustration and the evolution of function and structure at #ISMB2024

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Riccardo Percudani @percud.bsky.social · 14/07/2024

Rafael Najmanovich opens the 2nd day at #ISMB2024 Function Cosi talking about Fast, high-performance biophysics-based computational methods in function prediction.

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Riccardo Percudani @percud.bsky.social · 13/07/2024

Very inspiring talk by Valérie de Crécy-Lagard at the Function Cosi. Predicting protein function is gaining new knowledge, not transferring the known functions. AI is still unable to solve the first problem. #ISMB2024

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Riccardo Percudani @percud.bsky.social · 13/07/2024

Loved the Tandy Warnow Keynote at #ISMB2024 and how she made understandable complicated concepts about #phylogenomics

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Riccardo Percudani @percud.bsky.social · 19/06/2024

In pig-to-human kidney transplantation, we were about to forget a difference between humans and pigs. Our perspective in preprint on @JASN_News: journals.lww.com/jasn/citation/9900… #xenotransplantation, #evolution, #metabolism

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Riccardo Percudani @percud.bsky.social · 31/05/2024

The weirdest part of the top 1000 'best' scientists ranking is the French section, where @MicrobiomDigest's friend Didier Raoult is followed by @carlorovelli listed under the name 'Chiara'. research.com/scientists-rankings/be…

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Riccardo Percudani @percud.bsky.social · 21/05/2024

🚀 Call for PhD applications! Are you a driven graduate passionate about Data Science? 🌟 If you haven’t lived or worked in Italy for more than 1 year in the past 3 years, we want you! 👉 site.unibo.it/futuredata4eu 👈Apply now! #DataScience #ResearchOpportunity #GraduateJobs

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Riccardo Percudani @percud.bsky.social · 17/04/2024

The AI-generated Figure 3 still appears more appealing than the figures created by the authors 😜 x.com/strnr/status/1780698171943068…

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Riccardo Percudani @percud.bsky.social · 13/04/2024

Unlocking enzyme secrets with OSMES: our structure-based bioinformatics screening leverages AlphaFold models for identifying orphan enzymatic reactions 🔬🧬 #Bioinformatics #PathwayHoles. Just published: www.nature.com/articles/s41467-024-…

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Riccardo Percudani @percud.bsky.social · 02/02/2024

Interestingly, if you google "genetic code" the first results is an incorrect @genome_gov definition that blends the ideas of genetic code and coding sequence.

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Riccardo Percudani @percud.bsky.social · 28/12/2023

A novel study adds to the bonanza of primates genomes. Impressive graphics on the genome-phenome relations. www.science.org/doi/10.1126/science…

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Riccardo Percudani @percud.bsky.social · 27/12/2023

Thanks to a tweet, I learned that for the reconstruction of genes and pseudogenes by homology there are faster alternatives to @ewanbirney’s #genewise like @lh3lh3’s #miniprot.

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Riccardo Percudani @percud.bsky.social · 27/11/2023

Allegra Via glamorously introducing the success stories of @elixir_it Training Platform at the All Hands Meeting. #AHM

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Riccardo Percudani @percud.bsky.social · 27/11/2023

Bruno Fosso: how the Elixir Tools Platform can help scientists to identify the right software tools and workflows for their needs. @elixir_it All Hands Meeting. #AHM

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Riccardo Percudani @percud.bsky.social · 27/11/2023

Sivio Tosatto reporting on the Elixir Data platform and the importance of #biocuration at @elixir_it All Hands Meeting. #AHM

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Riccardo Percudani @percud.bsky.social · 27/11/2023

Andrew Smith presenting the @ELIXIREurope Scientific program 2024-2028 at the @elixir_it all hands, under the magnificent frescoes of the Sala Marconi of the CNR building in Rome.

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