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Penninger Lab

@penningerlab.bsky.social
513 followers 340 following 10 posts

We take a holistic approach to understand health & disease and research cancer, immunity, nervous system, heart, blood vessels, bone and glycoproteomics. We are located in Vienna, Braunschweig and Vancouver.

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Penninger Lab @penningerlab.bsky.social · 11/08/2026
Thrilled to share that our UrineScore paper is published in @embomolmed.org 🎉 A protein-based urine test for non-invasive detection of clear cell renal cell carcinoma: no blood, no biopsy, just urine. 🧪 Thanks to the team! @meduniwien.ac.at @imbavienna.bsky.social link.springer.com/article/10.1...
link.springer.com
Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma - EMBO Molecular Medicine
Clear cell renal cell carcinoma (ccRCC) is the most common kidney malignancy. Yet, no rapid, non-invasive biomarkers are available for diagnosis or screening. Urine represents an ideal analyte matrix ...
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Penninger Lab @penningerlab.bsky.social · 09/06/2026
Targeting glycosylation to sensitize breast cancer cells to immune therapy (make immunologically “cold tumors” into immunologically recognizable “hot tumors”). Thanks to @smereiter.bsky.social, the whole team and the T. Von Zastrow Foundation!
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Penninger Lab @penningerlab.bsky.social · 21/11/2025
Congratulations! Mariam successfully defended her master thesis „Mapping ACE2 dependency during SARS-CoV-2 infection” 👏🥂
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Institute of Molecular Biotechnology @imbavienna.bsky.social · 10/11/2025
Congratulations to Max Kellner, former PhD student in Josef Penninger’s lab, who was awarded a Vienna BioCenter PhD Award for his thesis, in which he developed bat-derived organoids to investigate why bats can carry highly pathogenic viruses without falling ill. More: imba.science/4r5X0TE
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Institute of Molecular Biotechnology @imbavienna.bsky.social · 25/09/2025
🎉 Congratulations to Max Kellner, former PhD student in the Penninger Lab, who was presented with the ÖGBMT Life Sciences PhD Award Austria. The award recognizes Kellner’s PhD research on how dangerous viruses emerge from natural reservoirs like bats. More: imba.science/3KiRYSN
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Helmholtz-Zentrum für Infektionsforschung (HZI) @helmholtzhzi.bsky.social · 15/07/2025
Molekulare Diagnostik ist in vielen Ländern nicht gut verfügbar. Forscher:innen des @viennabiocenter.bsky.social & @imbavienna.bsky.social, darunter @mjkellner.bsky.social, mittlerweile Gruppenleiter am HZI, stellen @lsajournal.org einen neuen Test vor. www.life-science-alliance.org/content/8/10...
life-science-alliance.org
A lyophilized open-source RT-LAMP assay for molecular diagnostics in resource-limited settings
A critical bottleneck for equitable access to population-scale molecular diagnostics is the limited availability of rapid, inexpensive point-of-care tests, especially in low- and middle-income countri...
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Penninger Lab @penningerlab.bsky.social · 22/05/2025
An organoid platform to study bats' resilience to viral infections - spearheaded by Max and supported by a great team & collaborators: www.nature.com/articles/s41...
nature.com
Bat organoids reveal antiviral responses at epithelial surfaces - Nature Immunology
Kellner et al. develop respiratory and intestinal organoids from Rousettus aegyptiacus to show elevated basal expression of interferon-ε (IFNε) and IFN-stimulated genes, along with robust, self-amplif...
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Penninger Lab @penningerlab.bsky.social · 21/05/2025
🎓🧫🔬 Join our lab at Medical University of Vienna as a PhD student investigating glycobiology and cancer research! Details below 👇
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Helmholtz-Zentrum für Infektionsforschung (HZI) @helmholtzhzi.bsky.social · 21/05/2025
🦇 Fledertiere können verschiedene hochgefährliche Viren in sich tragen, ohne sichtbar zu erkranken. @mjkellner.bsky.social & @penningerlab.bsky.social haben nun die zellulären antiviralen Abwehrmechanismen in den Schleimhäuten der Tiere untersucht. www.helmholtz-hzi.de/media-center...
Lichtmikroskopische Aufnahme eines Darmorganoides aus Gewebe von Nilflughunden
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Penninger Lab @penningerlab.bsky.social · 22/04/2025
Great collaboration on blood vessel organoids to model human vascular development and disease 🧫🔬
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Penninger Lab @penningerlab.bsky.social · 02/04/2025
For research times have become more difficult in many places. We want to spread positivity and show appreciation for our city: We enjoy living and conducting research in Vienna – great science, hospitals, people & art! #IchForscheGernInWien #Wien
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Penninger Lab @penningerlab.bsky.social · 10/02/2025
Huge congrats to Gustav Jonsson on his successful completion of his PhD studying biomarkers of clear cell renal cell carcinoma! 💛 #proudlab
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Penninger Lab @penningerlab.bsky.social · 31/01/2025
Proud of Max Kellner, who defended his PhD this week. A successful conclusion of his PhD journey and start of his own group very soon! 🦇🧫🦠
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Stefan Mereiter @smereiter.bsky.social · 19/11/2024
1/ Hi 🦋! Did you know? Glycans—complex sugar structures—decorate almost every protein processed by the ER/Golgi. These N-glycans coat our cells, playing critical roles in cell interactions and immune processes. 🍬 Curious about how they vary? Let’s dive in! #GlycoTime
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Penninger Lab @penningerlab.bsky.social · 06/12/2024
Perfect for our first post: big collaborate effort spearheaded by Masahiro Onji showing how sex hormones and RANK regulate gut expansion during reproduction 🤰🤱
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