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Univ. of Pennsylvania Department of Cancer Biology

@penncbio.bsky.social
36 followers 15 following 2 posts

Official Twitter of the Department of Cancer Biology at The University of Pennsylvania Perelman School of Medicine (@pennmedicine.bsky.social). Tweets are our own.

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Reposted by Univ. of Pennsylvania Department of Cancer Biology
Vikram Paralkar @paralkarlab.bsky.social · 02/08/2025
📣 New preprint 📣 We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation. Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)
biorxiv.org
Dynamics of Ribosomal RNA Transcription and Abundance in Normal and Leukemic Hematopoiesis
Transcription of ribosomal RNAs (rRNAs) from rDNA repeats is the first step of ribosome biogenesis, accounting for a major portion of all cellular transcription. Often regarded as a housekeeping proce...
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Reposted by Univ. of Pennsylvania Department of Cancer Biology
CAMB Graduate Group @cambupenn.bsky.social · 27/08/2025
Amy Gladstein in the Feldser lab defends her thesis tomorrow!
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Reposted by Univ. of Pennsylvania Department of Cancer Biology
American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 20/08/2025
#TuesdayMotivation | Meet Donita Brady (@bradylabupenn.bsky.social) at @pennmedicine.bsky.social (@penncbio.bsky.social & @rtaatpennmed.bsky.social): ow.ly/2hbi50WIzuM. Her lab investigates how copper modulates signal transduction in healthy and cancerous cells. #CancerResearch #tumorigenesis
ow.ly
Meet Donita Brady
Donita Brady is an associate professor of cancer biology and an associate editor of the Journal of Biological Chemistry, who studies metalloallostery in cancer.
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Reposted by Univ. of Pennsylvania Department of Cancer Biology
CAMB Graduate Group @cambupenn.bsky.social · 18/06/2025
New preprint for Amy Gladstein (@amygladstein) in the @Feldserlab on: The H3 K36M oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer pubmed.ncbi.nlm.nih.gov/40501771/
pubmed.ncbi.nlm.nih.gov
The H3 K36M oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer - PubMed
Mutations in histone 3 at or near lysine 36 (H3K36) have dominantly acting oncogenic effects in multiple tumor types by limiting H3K36-directed methyltransferases. Paradoxically, we find that…
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Univ. of Pennsylvania Department of Cancer Biology @penncbio.bsky.social · 10/06/2025
Learn more about 2-PREVENT Breast Cancer Translational Center for Excellence led by @angiedemichele.bsky.social & @penncbio.bsky.social chair Lewis Chodosh to identify and treat dormant breast cancer to forestall recurrence.
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Univ. of Pennsylvania Department of Cancer Biology @penncbio.bsky.social · 09/03/2025
We're excited to launch the official BlueSky account of the Department of Cancer Biology @pennmedicine.bsky.social. Stay tuned for our upcoming faculty search ad, highlights from our published research discoveries, and other departmental news! med.upenn.edu/cbio/
med.upenn.edu
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