Scott Dietrich @pcc-pharmd.bsky.social · 11/12/2025Why, why, why did we not report any data based on the dose? We know ketamine is more likely to induce BP reductions in pts with a +shock index Baseline SI was 0.93 and 65% of the ket group got >1.5 mg/kg. I bet the #’s are diff for low dose vs high pubmed.ncbi.nlm.nih.gov/27130803/ 110 0
Scott Dietrich @pcc-pharmd.bsky.social · 07/08/2025New ED pharmD study on lytics for PE-arrest with both tPA and TNK pt's ROSC seen in 9/21 with tPA vs only 2/11 with TNK. Not a huge study, but super interesting to see if another study comes out with similar tPA > TNK results bit.ly/4mbUqYG 131 0
Scott Dietrich @pcc-pharmd.bsky.social · 07/08/2025So funny b/c a pt with this past culture is in the ED today. Very timely posts 010 0
Scott Dietrich @pcc-pharmd.bsky.social · 24/05/2025New SRMA in-press with 6 studies comparing re-arrest rates post-ROSC btwn epi and norepi gtts with NE showing lower re-arrest rates and a non-significant increase is survival to discharge Should likely be doing NE gtts in most everyone post-ROSC at this point 140 0
Scott Dietrich @pcc-pharmd.bsky.social · 24/04/2025We're trying steroids and vasopressin again in IHCA Small pilot study showing benefit, remains to be seen on a larger scale if the results hold up or not, but 38% vs 16% ROSC looks good www.sciencedirect.com/science/arti... 041 0
Scott Dietrich @pcc-pharmd.bsky.social · 25/12/2024New (open access) study testing non-specific reversal agents against milvexian (a factor XI inhibitor). Looks like aPCC would be the early front runner in terms of effectiveness in vitro bit.ly/41NO0Im 240 0
Scott Dietrich @pcc-pharmd.bsky.social · 18/12/2024New pediatric study in press by Colorado PharmDs showing no diff in pain relief for ketorolac doses >15 mg (avg 0.44 mg/kg) vs capped doses of 15 mg (avg 0.26 mg/kg) aligning with adult literature 110 0
Scott Dietrich @pcc-pharmd.bsky.social · 07/12/2024I think we all already knew this, but new study showing benzo + olanzapine just as safe as olanzapine monotherapy in acutely agitated ED patients with low rates of cardiorespiratory depression bit.ly/3Zqdf0D 160 0