A two-part story about medicine under pressure.

A recent federal announcement to combat tick-borne disease has a promising premise but deserves scrutiny.

Part #2 of my Love-Hate Series: Email -- the miracle that connects us, buries us, and sends a “gentle reminder.”

Ensitrelvir reduced Covid-19 incidence 67% in household contacts of active cases.

Staph aureus in an unexpected place, sinus fungal balls, “explosive pleuritis”, and other lessons from 2 weeks on the consult service

Antibiotics, diagnostics, and other sources of professional ambivalence.

Including a video making its big premiere, plus a few other entertaining subjects of note.

Why aren’t we using it?

Twenty facts about a surprisingly common group of infections.

My guess: not much, as long as they’re taking good care of you.

Tofacitinib is used to treat certain types of arthritis (such as psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis). It helps to decre

Dr. Paul Sax rounds up key takeaways from CROI 2026, the leading HIV research conference.

Is it time to replace annual N95 mask fit testing with a less expensive, evidence-based policy?

This isn't really about raccoon bites.

CROI, which just wrapped up in Denver, is not like other scientific meetings — it’s quirky. Let me count the ways. There’s the name — the Conference on Retroviruses and Opportunistic Infections — coin...

Share Tweet Pin Mail SMS Any time I write about vaccines, especially mRNA vaccines, things get dicey. Any negative comments might fuel attacks from ...

Learning how to teach, forty minutes at a time.

Share Tweet Pin Mail SMS If you’re not using AI in clinical medicine yet, allow me to strongly recommend you start — soon. Like ...

Or, how I ended up teaching at a boarding school instead of pipetting in a research lab.

A Happy Birthday to a landmark policy change.

A personal exploration of an unpopular view.

A Happy Birthday to a landmark policy change

Three case reports of human rabies recently appeared in the MMWR. Reading each one served as a reminder of just how horrifying this infection is when it strikes — which very fortunately is quite rare ...

Dr. Paul Sax offers a “Strep Infections 101” course — the ones you should remember, and why, with perhaps a few fun facts thrown in.

The origins of "How to Figure Out the Length of Antibiotic Therapy"

In what feels like the fastest-peaking influenza season in quite some time, I find myself returning to a familiar answer when asked questions about this miserable virus: “We just don’t know.” At least...

Checking in at the three-month point in this writing journey.

Share Tweet Pin Mail SMS Part 1 of this azithromycin series explained how the drug became ubiquitous. In Part 2, we’ll explore why many ...

A Happy New Year gift to me and everyone who shares one or both of these enthusiasms.

Chances are, across this great land of ours, right at this very moment, someone is coughing, or sneezing, or struggling with a sore throat, or some combination of the above, and taking the antibiotic ...

Looking at radiology images, then and now.

Some statements are wrong enough to make your head explode.