npj Breast Cancer - Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance

Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis / Berthe Hayar, cancer, Cathrin Brisken, Ciara Metcalfe, George Sflomos, Karim

Patrick Aouad: Major Preclinical Models Used to Study Breast Cancer Metastasis / Berthe Hayar, cancer, Cathrin Brisken, Ciara Metcalfe, George Sflomos, Karim

npj Breast Cancer - Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance

Despite several decades of research that has revealed roles in the development and progression of many solid tumours, clinical translation of research targeting epithelial–mesenchymal transition (EMT)...

Liang et al. study the impact of ERα antagonist/degraders against different Esr1 mutations in murine models and find that inhibition of mutant ERα induces lineage plasticity, which is also observed in...

More than two-thirds of cancer-related deaths are attributable to metastases. In some tumor types metastasis can occur up to 20 years after diagnosis and successful treatment of the primary tumor, a ...