Lux @pathparazzi.bsky.social · 14/12/2025A rarity - colleague's case. Young man c/o testicular swelling for a month which he attributed to contact sports. Then upon workup was found to have a very high b-hCG and lung mets. Orchiectomy showed pure choriocarcinoma. This focus here shows LVI. #PathSky 041 4
Lux @pathparazzi.bsky.social · 17/10/2025Look at this perfect lil focus of LVI (invasive mucinous carcinoma of the breast). #PathSky 082 8
Lux @pathparazzi.bsky.social · 29/08/2025A classic my breast attending would present on at conferences - usual ductal hyperplasia with comedo type necrosis. This finding was seen in a radial scar. Important not to overcall! #PathSky 030 3
Lux @pathparazzi.bsky.social · 20/08/2025Consult from a colleague. Radical prostatectomy for prostate cancer and incidental CIS cancerizing the ducts. A doubly justified surgery. #PathSky 030 3
Lux @pathparazzi.bsky.social · 29/07/2025Older woman with history of breast cancer. New focus found on imaging mid chemo regimen. My initial concern was heme related until these stained nicely for CAM5.2. This is treated invasive ductal carcinoma. #PathSky 051 5
Lux @pathparazzi.bsky.social · 11/07/2025Nothing particularly interesting - prostatic adenocarcinoma with a mitosis that reminds me of the Batwing. Also been experimenting with raw images on my iPhone and editing them. Curious if there's a difference in sharpness. #PathSky 040 4
Lux @pathparazzi.bsky.social · 29/05/2025Soft tissue mass in the axilla. S100 and SOX10+, no h/o skin malignancies. An example of a Schwannoma with ancient changes. #PathSky 000 0
Lux @pathparazzi.bsky.social · 23/05/2025I swear I see more interesting breast diagnoses in private practice than I ever did at academic institutions. Invasive micropapillary carcinoma from today's pile. #PathSky 050 5
Lux @pathparazzi.bsky.social · 14/05/2025A beautiful glomangioma! Presented on the forearm of an older man. #PathSky 010 1
Lux @pathparazzi.bsky.social · 06/05/2025Biopsy of one of multiple white patches seen in esophagus. H&E showed no acute inflammation and only the barest hint of parakeratosis. No glycogenic acanthosis either. GMS teased out these critters. #PathSky 010 1
Lux @pathparazzi.bsky.social · 29/04/2025Corpora amylacea in prostate adenocarcinoma, an uncommon sighting. #PathSky 030 3
Lux @pathparazzi.bsky.social · 18/04/2025Another case from this past week. Lung biopsy for new lung nodule suspected to be cancer. Nearly thought I had to sign out medical lung but then I saw granulomas with asteroid bodies. And then the numerous yeast! Currently pending cultures and PCR. #PathSky 041 4
Lux @pathparazzi.bsky.social · 04/04/2025A slightly messy set of pictures. Young female, breast mass, post partum. This is a lactating adenoma with infarction. I love seeing entities I only previously read or heard about. #PathSky 052 5
Lux @pathparazzi.bsky.social · 02/04/2025Gastric biopsy in an older male with a history of anemia. If I weren't in private practice I would have done the iron stain but I did the next best thing and confirmed he was taking iron sulfate. #PathSky 041 4
Lux @pathparazzi.bsky.social · 20/03/2025Work enemy is acting up today and I want him to stub his toe real bad. Here's a beautiful pleomorphic adenoma from the submandibular gland! #PathSky 031 3
Lux @pathparazzi.bsky.social · 20/03/2025Colleague's case. They were very kind to share this with me. There was a clinical concern for malignancy and this biopsy thankfully will get the patient the appropriate line of treatment. Likely hepatic sarcoid. #PathSky 052 5
Lux @pathparazzi.bsky.social · 18/03/2025For some reason the clinician didn't think this was a horn. Regardless, a beautiful little squamous cell ca in situ. #PathSky 031 3
Lux @pathparazzi.bsky.social · 06/03/2025No shade to my GI peeps but I feel like I rarely get good pancreatic FNAs. This was a great one and stained nicely with INSM1, synapto, and chromo. Overkill IHC but it was nice to see. #PathSky 040 4
Lux @pathparazzi.bsky.social · 04/03/2025Clear cell cribriform hyperplasia with lipofuscin. A benign finding with a benign finding. #PathSky 050 5
Lux @pathparazzi.bsky.social · 01/03/2025Granular cell tumor found in the breast. Beautifully S100 positive (not pictured sadly). #PathSky 0103 10
Lux @pathparazzi.bsky.social · 18/02/2025Breast tissue. I feel like the duct is reminding me of a leafy seadragon. #PathSky 040 4
Lux @pathparazzi.bsky.social · 13/02/2025The ugliest urothelial carcinoma I've seen in a while. #PathSky 190 9
Lux @pathparazzi.bsky.social · 12/02/2025Fibrin thrombi at the periphery of an angiolipoma. It's the little things. #PathSky 081 8
Lux @pathparazzi.bsky.social · 10/02/2025I've officially made a work enemy ❤️ Anyhow something that stuck with me since residency is how these adenomas can have a shuttering artifact. Unsure why they do that. A soft sign of sorts at best. #PathSky 130 3
Lux @pathparazzi.bsky.social · 08/02/2025Looks like pleomorphic/grade 3 lobular initially. E-cad only partly lost and p120 catenin had mixed membranous and cytoplasmic expression. Areas with ductal feat elsewhere. Final dx - Invasive carcinoma with ductal/lobular features. #PathSky 061 6
Lux @pathparazzi.bsky.social · 08/02/2025Breast biopsy from a young teen. Noted to be circumscribed and oval on imaging. Biopsy showed diffuse PASH instead which was a relief. #PathSky 051 5
Lux @pathparazzi.bsky.social · 06/02/2025I hate looking for lone plasma cells in endometrial biopsies but sometimes they present themselves quite readily. #PathSky 040 4
Lux @pathparazzi.bsky.social · 05/02/2025I've never seen tyrosine crystals in a live pleomorphic adenoma until now and they're beautiful! Only took what, 7 years into path, to finally see one? #PathSky 170 7
Lux @pathparazzi.bsky.social · 31/01/2025Mucocele-like lesion on breast core needle biopsy. Never saw one in residency but just came across two this past week while looking at priors. Thankfully no malignancy associated with it. #PathSky 041 4
Lux @pathparazzi.bsky.social · 28/01/2025I spy with my weary eye a cell that is not like the others around it. #PathSky 020 2
Lux @pathparazzi.bsky.social · 25/01/2025A vessel twisting like a river. Happy Friday #PathSky 0101 10
Lux @pathparazzi.bsky.social · 22/01/2025Second week is going... 😂 Anyway here's a spindle cell GIST that was found on an GI workup. Noted to be perigastric and stained very nicely for DOG1 and CD117. #PathSky 090 9
Lux @pathparazzi.bsky.social · 18/01/2025Survived my first week! Here's a beautiful example of melanosis coli that I came across. 061 6
Lux @pathparazzi.bsky.social · 15/01/2025New year, new job, new post! A pterygium excised from a young woman's eye. There's a nicely demonstrable area of elastosis. #PathSky 0111 11
Lux @pathparazzi.bsky.social · 09/12/2024A subtle CIS and then a very obvious HGUC, same bladder. #PathSky 090 9
Lux @pathparazzi.bsky.social · 06/12/2024Small bowel resection, came as a ditzel with no history on the req other than anastomotic leak. As a colleague put it - Friday scaries. Malignant mesothelioma involving the bowel wall. Younger patient too 😩. #PathSky 081 8
Lux @pathparazzi.bsky.social · 04/12/2024I love a good intact corpus amylaceum. When near the prostatic urethra they can adopt various colors. This one in particular has vivid hues of yellow and purple. #PathSky 0123 12
Lux @pathparazzi.bsky.social · 03/12/2024A whole lotta acute inflammation and debris in a prostate, no carcinoma. If you're ever curious about whether or not there's real necrosis, I think this helps out. Unless you see actual cells dying into the lumen, don't call it pattern 5. It could just be inflammatory debris 🤷🏻♂️ #PathSky 060 6
Lux @pathparazzi.bsky.social · 28/11/2024A pre-Thanksgiving fun finding. Liver explant for cryptogenic cirrhosis in a 60+ yo M. Suspected A1AT. Could these globules represent misfolded protein? (Don't @ me, I'm genuinely awful at liver.) #PathSky 3132 13
Lux @pathparazzi.bsky.social · 27/11/2024TURP for LUTS. Pt has had a hx of previous catheterization and now there's an incidental nephrogenic adenoma. Never seen one in this type of specimen before. #PathSky 070 7
Lux @pathparazzi.bsky.social · 26/11/2024One of my favorite diagnoses - intraductal carcinoma of the prostate. Dare I say that this shows pleomorphic features? #PathSky 0151 15
Lux @pathparazzi.bsky.social · 25/11/2024What I imagine this conversation to have been: PA: Which color ink did you use? Resident: Yes. #PathSky 190 9