paoloactis.bsky.social @paoloactis.bsky.social · 19/08/2025Exciting work led by @nano-chalmers.bsky.social delivered in collaboration with @georgerheath.bsky.social introducing a rationally designed DNA origami system for the multiplexed detection of miRNA in crude RNA extracts via nanopore sensing. 2105
Reposted by @paoloactis.bsky.socialRiboCode @ribocode.bsky.social · 06/03/2025❗NEW PAPER❗ Check out our review on #ribosome heterogeneity and specialisation published today! We discuss the mechanisms of specialisation, review the latest research and explore how technological advancements will drive the next set of research questions. doi.org/10.1098/rstb.2023.0377 (1/2)doi.orgSpecialized ribosomes: integrating new insights and current challenges | Philosophical Transactions of the Royal Society B: Biological SciencesVariation in the composition of different ribosomes, termed ribosome heterogeneity, is a now well established phenomenon. However, the functional implications of this heterogeneity on the regulation of protein synthesis are only now beginning to be ... 044
Reposted by @paoloactis.bsky.socialRiboCode @ribocode.bsky.social · 27/01/2025Super exciting new paper from three of our brilliant RiboCoders and Nikki Weckman exploring the use of solid-state nanopore in monitoring enzyme digestion pubs.acs.org/doi/10.1021/... Congrats @nano-chalmers.bsky.social @paoloactis.bsky.social and Emma Thomson! Artwork inspired by Joy Division 👌pubs.acs.org 022
paoloactis.bsky.social @paoloactis.bsky.social · 20/01/2025Reposted linking @nano-chalmers.bsky.social who led, designed and delivered this work !!! 000
paoloactis.bsky.social @paoloactis.bsky.social · 20/01/2025We cannot join #SMPS4 but hot off the press our nanopore work to monitor CAS9 reactivity and its off-target effects. pubs.acs.org/doi/10.1021/...pubs.acs.orgSolid-State Nanopore Real-Time Assay for Monitoring Cas9 Endonuclease ReactivityThe field of nanopore sensing is now moving beyond nucleic acid sequencing. An exciting avenue is the use of nanopore platforms for the monitoring of biochemical reactions. Biological nanopores have b... 3154
Reposted by @paoloactis.bsky.socialRiboCode @ribocode.bsky.social · 28/11/2024 Come and join RiboCode! Are you interested in understanding the mechanisms of mRNA translation? Do you have experience using D. melanogaster? Would you like to join an interdisciplinary team? If so, apply for our Senior Research Technician role @universityofleeds.bsky.social shorturl.at/ytnrAjobs.leeds.ac.ukJob Opportunity at University of Leeds: Senior Research Technician in Gene ExpressionAre you an experienced technician looking for a challenge? Do you have a background in gene expression and RNA biology? Do you have experience in using model organisms? Do you want to further your c... 023
