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Dave Pagliarini

@pagliarini-lab.bsky.social
58 followers 14 following 4 posts

HHMI Investigator | BJC Investigator Hugo F. and Ina C. Urbauer Professor, WashU Medicine Departments of Cell Biology & Physiology Genetics | Biochemistry & Molecular Biophysics

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Dave Pagliarini @pagliarini-lab.bsky.social · 29/09/2026
Is phosphorylation broadly relevant to mitochondrial protein function? In work led by @aj-smith.bsky.social, we silenced 10 mito phosphatases, mapped dynamic sites, and revealed functional implications for import, catalysis, and morphology. www.biorxiv.org/content/10.6... # Mitochondria #HHMINews
biorxiv.org
Dynamic protein phosphorylation shapes mitochondrial catalysis, import, and architecture
Phosphorylation is a pervasive mitochondrial protein post-translational modification, yet the extent of its influence over mitochondrial functions remains unclear. To identify dynamic mitochondrial ph...
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Dave Pagliarini @pagliarini-lab.bsky.social · 10/06/2026
PI is a prominent #mitochondrial lipid but little is known about its regulation and function. In work led by Zak Baker and Rachel Guerra, we discovered that Fmp30p is a PI hydrolase that affects IM protein organization and CoQ production. #HHMInews #WashU www.nature.com/articles/s41...
nature.com
Fmp30p is a mitochondrial phosphatidylinositol hydrolase that modulates CoQ biosynthesis - Nature Communications
The mechanisms contributing to organellar membrane lipid composition remain unclear. Here, Baker and Guerra et al. characterize the mitochondrial protein Fmp30p as a phosphatidylinositol (PI) phosphol...
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Dave Pagliarini @pagliarini-lab.bsky.social · 12/12/2025
Attention undergraduates: 10 days left to apply for the new HHMI Cech Fellows program — a nine-week summer research experience that provides rising juniors and seniors with a $15K stipend, or $12K plus housing for those placed at Janelia.  @hhsofficial.bsky.social #HHMI www.hhmi.org/programs/cec...
hhmi.org
Summer Undergraduate Research Experience (REU) | Cech Fellows | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
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Dave Pagliarini @pagliarini-lab.bsky.social · 22/07/2025
Registration is open (and free) for this year's Midwest Metabolism/Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) Annual Conference at the University of Michigan November 10–11, 2025. Hope to see you there! www.vai.org/event/2025-m...
vai.org
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
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