Is phosphorylation broadly relevant to mitochondrial protein function? In work led by @aj-smith.bsky.social, we silenced 10 mito phosphatases, mapped dynamic sites, and revealed functional implications for import, catalysis, and morphology.
www.biorxiv.org/content/10.6...
# Mitochondria
#HHMINews
biorxiv.org
Dynamic protein phosphorylation shapes mitochondrial catalysis, import, and architecture
Phosphorylation is a pervasive mitochondrial protein post-translational modification, yet the extent of its influence over mitochondrial functions remains unclear. To identify dynamic mitochondrial ph...