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Ouli Xie

@ouli-xie.bsky.social
10 followers 22 following 13 posts

Infectious diseases physician, clinician-scientist, working on pathogen genomics and evolution. ESPOD fellow @Wellcome Sanger Institute and European Bioinformatics Institute.

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Ouli Xie @ouli-xie.bsky.social · 04/08/2026
Can Group C/G Streptococcus (Streptococcus dysgalactiae subsp. equisimilis, SDSE) become penicillin resistant? We report a case in an individual on prolonged penicillin prophylaxis. doi.org/10.1128/aac.... @steventong.bsky.social @thedohertyinst.bsky.social 🧵👇
doi.org
Penicillin-resistant Streptococcus dysgalactiae subsp. equisimilis and the association with penicillin-binding protein mutations: a population genotypic and phenotypic study | Antimicrobial Agents and Chemotherapy
Streptococcus dysgalactiae subspecies equisimilis (SDSE, commonly referred to as Group C/G Streptococcus) is increasingly recognized as a cause of serious human disease (1). SDSE is closely related to Streptococcus pyogenes with overlapping disease manifestations (1, 2). Incidence of invasive SDSE disease is comparable or even exceeds that of S. pyogenes in some countries, but surveillance lags behind that of its more well-studied relative (2–4).
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Ouli Xie @ouli-xie.bsky.social · 24/04/2026
Pleased to share our latest paper published in @natmicrobiol.nature.com on the emergence of antimicrobial resistant S. pyogenes lineages driving scarlet fever in China - a collaboration between Dr Yuanhai You, the China CDC and the Davies and Walker labs @thedohertyinst.bsky.social dlvr.it/TSB4lx 🧵👇
dlvr.it
Emergence of distinct Streptococcus pyogenes emm1 and emm12 lineages in China - Nature Microbiology
Genomic epidemiology of 1,029 Streptococcus pyogenes emm1 and emm12 genome sequences collected between 1993 and 2024 in China reveals dominance of distinct lineages with mobile genetic element-encoded...
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